Interval estimation of the 90% effective dose: a comparison of bootstrap resampling methods with some large-sample approaches

A number of recent studies have looked at the coverage probabilities of various common parametric methods of interval estimation of the median effective dose (ED 50 ) for a logistic dose-response curve. There has been comparatively little work done on more extreme effective doses. In this paper, the interval estimation of the 90% effective dose (ED 90 ) will be of principal interest. We provide a comparison of four parametric methods of interval construction with four methods based on bootstrap resampling.     

Predictors of High-Risk Sexual Behavior Among Individuals Living with HIV Disease and AIDS

An important focus of the 1996 World Aids Conference related to the extent of unprotected sex among gay men, particularly those in their twenties. This paper will use logistic analysis to explore the extent of unsafe sexual practices among individuals living in Bexar County, Texas, who are HIV+ assymptomatic, HIV+ symptomatic, or have AIDS. Using survey research data, we assess the significance and impact of various independent factors on whether respondents reported they did or did not engage in unprotected sex. The most striking finding is that unprotected sexual activity is prevalent regardless of demographic and/or status differences among respondents. Findings reinforce the use of community planning processes, which emphasize the importance of sound behavioral and social science combined with efforts to include the affected constituency to create effective HIV prevention programs.     

Gender Role Ideology and the Gender Based Differences in Earnings

Much of the research on gender differences in occupational earnings still focuses on human capital and the structure of the labor market. However, these variables rarely explain even half of the gender gap in earnings. Most research has examined the impact of gender role ideology as it impacts occupational choice, which indirectly can impact earnings. Using data from the National Opinion Research Center General Social Surveys, this research focuses on the relationship between attitudes about gender roles and two variables: (a) earnings, and (b) occupational positions held by women and men. Findings show that traditional gender-role ideology contributes to lower observed earnings for both males and females, independent of the influences of human capital characteristics, occupational context, and ascribed characteristics. Results support socialization as a partial explanation for the gender-based earnings differences and suggest that, to the extent that economic rewards are used to assess the value of gender role expectations, traditional gender role attitudes might continue to change and lead to relatively equal earnings among women and men.     

Dynamic Choices of Hyperbolic Consumers

Laboratory and field studies of time preference find that discount rates are much greater in the short‐run than in the long‐run. Hyperbolic discount functions capture this property. This paper solves the decision problem of a hyperbolic consumer who faces stochastic income and a borrowing constraint. The paper uses the bounded variation calculus to derive the Hyperbolic Euler Relation, a natural generalization of the standard Exponential Euler Relation. The Hyperbolic Euler Relation implies that consumers act as if they have endogenous rates of time preference that rise and fall with the future marginal propensity to consume (e.g., discount rates that endogenously range from 5% to 41% for the example discussed in the paper).     

Mathematical Methods in Combatting Terrorism

This document is a preliminary report on the role that mathematical and statistical methods might play in the defense against terrorist attacks. In no way does this replace the efforts of law enforcement agencies or intelligence activities. The hope is that mathematical techniques can make their efforts more efficient. The ideas enumerated here utilize the notion of probabilistic risk analysis, which was developed for the purpose of assessing the safety of nuclear reactors, as well as randomization and game theory. More extensive work in these directions is contemplated for the future. The author is planning workshops to evaluate the ideas presented here and to elicit additional methodologies that may prove useful in this endeavor.     

REVIEWS

Becvar, D. S. (2001). In the presence of grief: Helping family members resolve death, dying, and bereavement issues .
Hoffman, L. (2002). Family therapy: An intimate history .
Keith, D. V., Connell, G. M., & Connell, L. C. (2001). Defiance in the family: Finding hope in therapy .
Ravicz, S. (2000). Thriving with your autoimmune disorder: A woman's mind-body guide .     

Behavioral science space contributions

In anticipation of longer missions on the space stations, Mir and Freedom, as well as a potential return to the Moon and the exploration of Mars, human survival and the quality of life aloft will be increasingly dependent upon research in the behavioral and biological sciences. This article reviews the possible contributions to space habitation of the behavioral sciences--especially anthropology, psychology, and sociology. Before space settlements become a reality, the author makes a case for the broadening of the engineering approach to human factor studies, and consideration of the integrative living systems theory in space planning and management.