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981.
Complementing previous literature on welfare reform and the character of jobs in the low-wage labour market, we illustrate the lack of regularity and security that mark the jobs held by many low-income mothers. To do so, we present a typology of mothers’ work patterns and illustrate their experiences through case examples. Our qualitative analysis of longitudinal pathways-to-work in three cities involved an examination of the experiences of 99 diverse, low-income working mothers with a young child. The work patterns that emerged from this analysis include: continuous duration of a single job; multiple job spells; underemployment; and churning in and out of employment. Findings indicate that a complicated ‘coming together’ of well-paying stable jobs, consistent aid from public systems and stable family networks are necessary for mothers to take even the first steps into stable employment.  相似文献   
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This paper provides a review of some of the literature addressing the juncture of disabilities and sexualities and invites sociologists to build on this work and take part in this important intersectional field. First, I discuss the central relevance of an intersectional lens for making sense of the unique experiences of queer people with disabilities who are located at the crossroads of various stratified systems. Then, I discuss some of the many unique challenges that queer disabled people face when exploring their sexuality, establishing relationships, and remaining sexual. The invisibility, marginalization, and discrimination of queer people with disabilities in both queer and disability communities are the focus on the third section. The fourth section speaks to current theoretical dialogues between disability studies and queer theory that have illuminated new pathways for theorizing the intersection of disabilities and sexualities, “cripping” sociological theories, and reimagining disability within sociology. As I demonstrate, this literature is growing; however, myriad exciting opportunities for empirical and theoretical sociological exploration remain and I will conclude with a discussion of possible directions for future research.  相似文献   
985.
In prior works, this group demonstrated the feasibility of valid adaptive sequential designs for crossover bioequivalence studies. In this paper, we extend the prior work to optimize adaptive sequential designs over a range of geometric mean test/reference ratios (GMRs) of 70–143% within each of two ranges of intra‐subject coefficient of variation (10–30% and 30–55%). These designs also introduce a futility decision for stopping the study after the first stage if there is sufficiently low likelihood of meeting bioequivalence criteria if the second stage were completed, as well as an upper limit on total study size. The optimized designs exhibited substantially improved performance characteristics over our previous adaptive sequential designs. Even though the optimized designs avoided undue inflation of type I error and maintained power at 80%, their average sample sizes were similar to or less than those of conventional single stage designs. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
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Accurate record keeping is an important part of the responsible conduct of research. However, there is very little empirical research on scientific record keeping. No one knows the incidence of serious problems with research records, the types of problems that occur, nor their consequences. In this study, we examined the role of research records in the resolution of misconduct allegations as a useful barometer for the incidence and types of problems that occur with records. We interviewed Research Integrity Officers (RIOs) at 90 major research universities and conducted focus groups with active research faculty. RIOs reported problems with research records in 38% of the 553 investigations they conducted. Severe problems with research records often prevented completion of investigations while problems that are more typical lengthened them by 2 to 3 weeks. Five types of poor record keeping practices accounted for 75 % of the problems with incomplete/inadequate records being the most common (30%). The focus groups concurred with the findings from the interviews with RIOs, stressed the importance of the research group leader in setting and maintaining record practices, and offered additional insights. While university officials and faculty members have suspected for many years that there are serious problems with research record keeping, our study provides empirical evidence for this belief. By documenting some of the problems with record keeping in university-based research, the results of our study provide information that will be useful for policy development at academic institutions.  相似文献   
989.
This article promotes integrating assessment and evidence-based practice in the treatment of traumatized children through a review of two newly developed trauma assessment tools: (1) the Child Welfare Trauma Referral Tool (CWT), and (2) Assessment-Based Treatment for Traumatized Children: A Trauma Assessment Pathway Model (TAP). These tools use pathways and algorithms to increase understanding of individual child trauma victims, and assist professionals working with children to make appropriate referral and treatment decisions within both child welfare and mental health contexts.  相似文献   
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