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261.
Objective: To estimate the impact ofarthritis using a general health index andNational Health Interview Survey (NHIS) data.Methods: Morbidity data came from NHISPublic Use data, from the years 1986–1988 and1994. The data are 423 400 cases, representing975 421 153 person-years. Quality ofWell-being Scale (QWB) morbidity scores wereimputed from NHIS questions about healthconditions and limitations in functioning. Both the QWB and multiple linear regressionwere used to estimate the effects of arthritiswith and without adjustments for co-morbidity. Mortality data for NHIS-sampled adults weredrawn from the National Death Index by staff ofthe National Center for Health Statistics.Results: The mean QWB for those withself-reported arthritis was 0.608 on a scaleranging from 0.0 (for death) to 1.0 (for fullyfunctional without symptoms or problems). Thisobserved mean for arthritis is 39.2% below the1.000 comparison standard. QWB morbidityscores for self-reported arthritis appear(0.701 – 0.608=) 9.3% more severe than meaneffects of all other health conditions. Mortality adds an average 13.8% to themorbidity burden. Persons with arthritisconstitute 4.7% of the population, but accountfor 9.6% of Quality-Adjusted Life Years(QALYs) lost to morbidity.Conclusions: Self-reported arthritis isassociated with very significant losses inQuality-Adjusted Life in the US population.  相似文献   
262.
No professional sports group ever achieved acceptance as widespread within a single decade's span as the American Football League (AFL). This study chronicles how the AFL used public relations strategies and tactics to garner public acceptance, which in turn helped convince the older National Football League (NFL) to merge with the upstart league. This study will further the understanding of how trade associations use public relations as an image-building device, as well as address a deficiency in the study of sports public relations.  相似文献   
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This paper describes the results of a study of innovation in the management teams of 27 UK hospitals. It is argued that the content of innovations provides an accurate representation of the underlying cultural values of the management teams, and the cultural values which they seek to purvey within the wider organizational settings. The authors propose that values in action (as opposed to espoused values) are manifest in the range of innovations introduced by top management within organizations. Using a typology of organizational culture, they categorize the innovations introduced by the management teams, in order to map their underlying cultural values. The results indicate predominant orientations of hospital management teams towards rational goal and hierarchical values in the current context of health care in Britain. Internal climate and service innovations were relatively infrequent, suggesting that the hospitals were dominated by management concern for control rather than flexibility. The costs of such cultural strategies in health service settings are discussed.  相似文献   
265.
Many experiments in research and development in the pharmaceutical industry involve mixture components. These are experiments in which the experimental factors are the ingredients of a mixture and the response variable is a function of the relative proportion of each ingredient, not its absolute amount. Thus the mixture ingredients cannot be varied independently. A common variation of the mixture experiment occurs when there are also one or more process factors that can be varied independently of each other and of the mixture components, leading to a mixture–process variable experiment. We discuss the design and analysis of these types of experiments, using tablet formulation as an example. Our objective is to encourage greater utilization of these techniques in pharmaceutical research and development. Copyright © 2004 John Wiley & Sons Ltd.  相似文献   
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The rate of fish consumption is a critical variable in the assessment of human health risk from water bodies affected by chemical contamination and in the establishment of federal and state Ambient Water Quality Criteria (AWQC). For 1973 and 1974, the National Marine Fisheries Service (NMFS) analyzed data on the consumption of salt-water finfish, shellfish, and freshwater finfish from all sources in 10 regions of the United States for three age groups in the general population: children (ages 1 through 11 years), teenagers (ages 12 through 18 years), and adults (ages 19 through 98 years). Even though the NMFS data reported in Ref. 14 are 20 years old, they remain the most complete data on the overall consumption of all fish by the general U.S. population and they have been widely used to select point values for consumption. Using three methods, we fit lognormal distributions to the results of the survey as analyzed and published in Ref. 14. Strong lognormal fits were obtained for most of the 90 separate data sets. These results cannot necessarily be used to model the consumption of fish by sport or subsistence anglers from specific sites or from single water bodies.  相似文献   
268.
In national surveys, around half of intimate partner violence perpetrators are also victims of partner assaults. However, data on intimate partner violence victimization and perpetration are rarely examined together. This study examines the relationships between perpetration, victimization, and three psychosocial variables—depression, self‐esteem, and substance abuse—that have been constructed in prior research as both causes and consequences of partner violence. Results indicate that associations between substance abuse and self‐esteem and partner violence perpetration are mediated by controlling for victimization, but depression is associated with both victimization and perpetration. Associations between mutual violence and depression and substance abuse are greater among women than men, supporting the position that gender symmetry in reported violence perpetration does not imply symmetry in outcomes.  相似文献   
269.
We investigated habitat use of Columbian black-tailed deer in urban Vancouver, Clark County, Washington, at 3 spatial scales: (1) placement of the annual home range within the landscape mosaic, (2) annual and seasonal locations of deer within the annual home range, and (3) short-term use of critical habitats (fawning areas) within seasonal ranges. Annual home range sizes of deer were 162 ha (SD = 133; 95% minimum convex polygon; MCP) and 266 ha (SD = 228; 95% adaptive kernel; AK) for does, and 756 ha (SD = 290; MCP) and 1,235 ha (SD = 382; AK) for bucks. Home range composition of does did not differ from the study area; home ranges of bucks contained more Natural ecological land-use cover types (ELUs) than did the study area. Within home ranges, both does and bucks used Natural ELUs more often than expected by their occurrence in the home range, both annually and seasonally. During the fawning season, does were also found in Natural ELUs more often than expected. Clark County-designated habitat corridors differed from both the study area and deer home ranges in habitat composition, primarily by containing more Natural and other undeveloped ELUs. Deer were located in habitat corridors more than expected. Deer in urban areas appear to use undeveloped habitat types for security. Management that maintains Natural ELUs, such as establishment of wildlife corridors, can provide important habitat components for black-tailed deer in urban habitats.  相似文献   
270.
Generalized discriminant analysis based on distances   总被引:14,自引:1,他引:13  
This paper describes a method of generalized discriminant analysis based on a dissimilarity matrix to test for differences in a priori groups of multivariate observations. Use of classical multidimensional scaling produces a low‐dimensional representation of the data for which Euclidean distances approximate the original dissimilarities. The resulting scores are then analysed using discriminant analysis, giving tests based on the canonical correlations. The asymptotic distributions of these statistics under permutations of the observations are shown to be invariant to changes in the distributions of the original variables, unlike the distributions of the multi‐response permutation test statistics which have been considered by other workers for testing differences among groups. This canonical method is applied to multivariate fish assemblage data, with Monte Carlo simulations to make power comparisons and to compare theoretical results and empirical distributions. The paper proposes classification based on distances. Error rates are estimated using cross‐validation.  相似文献   
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