The Evolution of Knowledge and the Dynamics of an Industry Network

The paper moves a step forward in the direction of establishing a connection between the structure and evolution of knowledge bases and the structure and evolution of organizational forms in innovative activities in a science-intensive industry. The paper has an explicit focus on the dynamics of the network of collaborative agreements in R&D in the pharma/biotech industry after the “molecular biology revolution”. Using a comprehensive dataset, built by the authors integrating several sources in the industry, the dynamics of the network over time is extensively analyzed. With regards to network structure, it is found that, while the size of the network increases over time due to net flows of entry, its topological properties remain relatively unchanged. The evolution of the network has occurred without relevant deformations in the core-periphery profile. With regards to age-dependent propensity to collaborate, the paper finds that the extent of inter-generational collaboration is much more significant than intra-generational collaboration. In addition, the propensity of firms of a given generation to enter into collaboration with firms of a different generation increases with the distance between the two, while the total number of intra-generational collaborations decreases over time and, moreover, tends to decrease for most recent generations. In the paper a unitary and coherent explanation of the evidence is developed, coming to reveal the existence of a striking isomorphism between structural properties of the dynamics of knowledge and of the evolution of network structure. This revised version was published online in July 2006 with corrections to the Cover Date.     

Developing Age-Friendly Cities: Case Studies From Brussels and Manchester and Implications for Policy and Practice

Developing environments responsive to the aspirations of older people has become a major concern for social and public policy. Policies and programs directed at achieving “age-friendly” communities are considered to require a wide range of interventions, including actions at the level of the social and physical environment. This article compares the age-friendly approaches of two European cities, Brussels and Manchester, with a particular focus on policies and initiatives that promote active aging in an urban context. The article examines, first, the demographic, social, and multicultural contexts of Brussels and Manchester; second, the way in which both cities became members of the World Health Organization Global Network of Age-Friendly Cities and Communities; third, similarities and differences in the age-friendly approaches and actions adopted by both cities; and fourth, opportunities and barriers to the implementation of age-friendly policies. The article concludes by discussing the key elements and resources needed to develop age-friendly cities.     

‘A lad tried to get hold of my boobs,so I kicked him’: an examination of attempts by adults with learning difficulties to initiate their own safeguarding

People with learning difficulties are considerably more likely to experience sexual and other forms of violence than non-disabled people. Nevertheless, several respondents in this study have demonstrated some self-protective competencies. Most knew of their right not to be violated and a number of participants described situations when they had attempted to initiate their own safeguarding. Some had asked others for help with this. However, appropriate assistance was not always provided. This indicates that risk may be aggravated by social barriers. This paper focuses on highlighting the resistance skills that are prevalent amongst some people with learning difficulties. It concludes with suggestions on ways in which individuals may be further supported to realise their potential to play a more active role in directing and regaining their own protection.     

Attitudes of Heterosexual Men and Women Toward HIV Negative and Positive Gay Men

Attitudes of Italian heterosexual men and women toward gay men, both HIV positive and negative, are poorly investigated. Italian culture is still extremely conservative and provides limited support to the gay community (e.g., lack of same-sex marriage recognition). Consequently, gay men experience social exclusion and disparities. The present study explores the association between homophobia and closeness with sexual orientation and HIV status. 261 heterosexual Italian men and women were assessed for feelings of closeness and homophobia after reading a vignette where the character was C1: heterosexual and HIV negative; C2: gay and HIV negative; or C3: gay and HIV positive. Experiences of homophobia and closeness varied depending on gender of participant and condition assigned, and higher levels of homophobia were correlated with lower levels of closeness regardless of HIV status. Implications and future directions are discussed.     

Physical exercise,nutrition and hormones: three pillars to fight sarcopenia

Background: Sarcopenia is a pathophysiological condition diffused in elderly people; it represents a social issue due to the longer life expectancy and the growing aging population. It affects negatively quality of life and it represents a risk factor for other pathologies, such as diabetes, cardiovascular disease, and obesity. No silver bullet exists to hinder sarcopenia, but it may be counteracted by physical exercise, nutrition, and a proper endocrine milieu. Indeed, we aim to analyze the scientific literature to give to clinician effective advices to counteract sarcopenia.

Main text: Physical exercise, proper nutrition, optimized hormonal homeostasis represent the three pillars to fight sarcopenia. Physical exercise represents the most effective remedy to face sarcopenia, in particular if it is combined with a proper diet and with an adequate endocrine milieu. Consistency in training, adequate daily protein intake and eugonadism seems to be the keys to fight sarcopenia. The combination of these three pillars might act synergistically.

Conclusions: Optimization of these factors may increase their efficiency; however, scientific data may be sometimes confusing so far. Therefore, we aim to give practical advices to clinician to identify and to highlight the most important aspects in each of these three factors that should be addressed.     

A study of search algorithms’ optimization speed

Search algorithms are often compared by the optimization speed achieved on some sets of cost functions. Here some properties of algorithms’ optimization speed are introduced and discussed. In particular, we show that determining whether a set of cost functions F admits a search algorithm having given optimization speed is an NP-complete problem. Further, we derive an explicit formula to calculate the best achievable optimization speed when F is closed under permutation. Finally, we show that the optimization speed achieved by some well-know optimization techniques can be much worse than the best theoretical value, at least on some sets of optimization benchmarks.     

“Phil's Calling Grandma… ”: The Role of External Support in Human–Companion Animal Identity Pairings

This exploratory paper deals with human–animal role identity pairings such as parent–child or sibling–sibling and the necessity of support from other actors both for the formation of these idiosyncratic identities, as well as for their situational placement in social environments not limited to the nonhuman animal. Taken from a qualitative study examining identity formation counter to the nonhuman animal, I use in‐depth interviews of both people with and without human children to demonstrate how human‐to‐human relationships are formed by categorizing the companion animal as a “child” of sorts within the family structure. These relationships prove integral to the continued development and enactment of identities such as the animal “parent” or the animal “sibling” via three different groups: their own parents, partners, and, in one case, adult siblings. This creates positive affect and commitment to the identity across other social situations. Implications of these findings for identity theory and family research are discussed.