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251.
This paper traces the history and metamorphosis of the National Registry of Health Care Providers in Clinical social Work. It was created in 1975 to credential qualified clinical social workers, and to identify them through a published directory. In 1987 it became the National Institute for Clinical Social Work Advancement. Its objectives and purposes moved from credentialling to advancing the speciality of clinical social work through research, education and marketing.  相似文献   
252.
Leveraging historical data into the design and analysis of phase 2 randomized controlled trials can improve efficiency of drug development programs. Such approaches can reduce sample size without loss of power. Potential issues arise when the current control arm is inconsistent with historical data, which may lead to biased estimates of treatment efficacy, loss of power, or inflated type 1 error. Consideration as to how to borrow historical information is important, and in particular, adjustment for prognostic factors should be considered. This paper will illustrate two motivating case studies of oncology Bayesian augmented control (BAC) trials. In the first example, a glioblastoma study, an informative prior was used for the control arm hazard rate. Sample size savings were 15% to 20% by using a BAC design. In the second example, a pancreatic cancer study, a hierarchical model borrowing method was used, which enabled the extent of borrowing to be determined by consistency of observed study data with historical studies. Supporting Bayesian analyses also adjusted for prognostic factors. Incorporating historical data via Bayesian trial design can provide sample size savings, reduce study duration, and enable a more scientific approach to development of novel therapies by avoiding excess recruitment to a control arm. Various sensitivity analyses are necessary to interpret results. Current industry efforts for data transparency have meaningful implications for access to patient‐level historical data, which, while not critical, is helpful to adjust for potential imbalances in prognostic factors.  相似文献   
253.
254.
The everyday is often seen as the time when nothing happens. This is a view that follows from a sense of chronological time, Euclidean space and Hegelian identity-play. The everyday can also be experienced as the time of eternity, the space of infinitude and the ontological condition of love. This epiphanic experience of the sacred is not of a release from the everyday but a return to it. The sacred is not the exception to the everyday but the ground of our everyday belonging to the universe.  相似文献   
255.
We examine how the content of actors' speech and the frequency with which they make contributions affect the emergence and legitimation of inequality in task groups. Previous research has focused on classifying acts, the smallest meaningful units of speech, such as providing opportunities to others to speak, making task relevant suggestions, and positively or negatively evaluating the contributions of others. We also employ a classification scheme based on the cognitive complexity of spoken language in the turn. This scheme is based on an interpretation of the cognitive development model posited by Piaget. In addition to the complexity of language, we analyze speech group members employ to organize to solve the task. These classifications rely on the entire content of the turn rather than the more atomistic act. Data analyzed are from 33 groups of students performing different types of tasks. We employ structural equation models to identify how acts and content are related to one another in the observed interaction patterns in groups. Applications of these insights are explored in the discussion.  相似文献   
256.

This article examines the changing role of important sections of the Chilean political elites, from a Keynesian and Marxist cultural political and economic ethos, to a post-modernist set of values profoundly influenced by the ideas of free markets and state withdrawal, as proposed by Hayek and Friedman. From strong support for, and identification with, the role of the state as agent of change, social justice and social mobility, significant sections of the Chilean political class have come to accept the globalisation of the world economy and its determination of internal politics. Values such as solidarity and equalitarianism have given way to individualism and selfishness. Whether these changes reflect genuine commitment or tactical adaptation remains to be seen, but they are likely anyway to undermine the legitimacy of the democratic regime which replaced the 16 year dictatorship of the military under General Augusto Pinochet. The lack of real alternative societal models does not augur well for the fragile Chilean democracy.  相似文献   
257.
This paper reports on the development and operationalisation of a partnership between researchers at the Centre for Child Care Research at Queens University, Belfast and the Southern Health and Social Services Board Training Unit to undertake an evaluation of the Children (NI) Order Training Programme. The concept of partnership and its application to researcher-practitioner relationships is discussed. The stages of development of the partnership between the Training Unit and the researchers, and the outcomes achieved from this partnership, are described. The similarities and differences between the partnership approach developed by the CCCR and the SHSSB are highlighted. The potential benefit of this approach for other researchers and practitioners seeking to develop such links is presented.  相似文献   
258.
Abstract

This paper investigates the reliability of the Occupational Stress Indicator (OSI). Data from a sample of university staff, drawn from all areas of an urban university, are used to reassess the apparently low reliabilities of many of the OSI subscales reported by Cooper et al. (1988). In addition, factor analysis results are reported for the first time for the sources of pressure data. The reliability data reported here, while higher reliabilities than originally obtained, remain unacceptably low. A lack of stability in the device as it is currently formulated seems apparent. The paper also presents for the first time a detailed analysis of the sources of pressure scale, indicating a solution different from that proposed by Cooper et al. (1988). Certain areas of the OSI clearly need refinement; the inclusion of locus of control and type A behaviour as personality variables in particular is called into question. Observations regarding the particular strengths and weaknesses of this device, and suggestions for future refinements, are offered.  相似文献   
259.
This article engages with the question of how theorisation of the social construction of childhood can be applied across cultural contexts, taking China and Britain as examples. The paper draws on collaborative dialogue between scholars from the People's Republic of China and Britain, and literatures from both Anglophone and Mandarin sources. It takes forward emergent work on theorising childhood from diverse global perspectives by focusing on the institutionalisation of childhood in these countries, with particular reference to language, conceptualisation and legal frameworks relating to chronological age.  相似文献   
260.
In this paper, a new nonparametric methodology is developed for testing whether the changing pattern of a response variable over multiple ordered sub-populations from one treatment group differs with the one from another treatment group. The question is formalized into a nonparametric two-sample comparison problem for the stochastic order among subsamples, through U-statistics with accommodations for zero-inflated distributions. A novel bootstrap procedure is proposed to obtain the critical values with given type I error. Following the procedure, bootstrapped p-values are obtained through simulated samples. It is proven that the distribution of the test statistics is independent from the underlying distributions of the subsamples, when certain sufficient statistics provided. Furthermore, this study also develops a feasible framework for power studies to determine sample sizes, which is necessary in real-world applications. Simulation results suggest that the test is consistent. The methodology is illustrated using a biological experiment with a split-plot design, and significant differences in changing patterns of seed weight between treatments are found with relative small subsample sizes.  相似文献   
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