On locally optimal invariant unbiased tests for the variance components ratio in mixed linear models

In the paper the problem of testing of two-sided hypotheses for variance components in mixed linear models is considered. When the uniformly most powerful invariant test does not exist (see e.g. Das and Sinha, in Proceedings of the second international Tampere conference in statistics, 1987; Gnot and Michalski, in Statistics 25:213–223, 1994; Michalski and Zmyślony, in Statistics 27:297–310, 1996) then to conduct the optimal statistical inference on model parameters a construction of a test with locally best properties is desirable, cf. Michalski (in Tatra Mountains Mathematical Publications 26:1–21, 2003). The main goal of this article is the construction of the locally best invariant unbiased test for a single variance component (or for a ratio of variance components). The result has been obtained utilizing Andersson’s and Wijsman’s approach connected with a representation of density function of maximal invariant (Andersson, in Ann Stat 10:955–961, 1982; Wijsman, in Proceedings of fifth Berk Symp Math Statist Prob 1:389–400, 1967; Wijsman, in Sankhyā A 48:1–42, 1986; Khuri et al., in Statistical tests for mixed linear models, 1998) and from generalized Neyman–Pearson Lemma (Dantzig and Wald, in Ann Math Stat 22:87–93, 1951; Rao, in Linear statistical inference and its applications, 1973). One selected real example of an unbalanced mixed linear model is given, for which the power functions of the LBIU test and Wald’s test (the F-test in ANOVA model) are computed, and compared with the attainable upper bound of power obtained by using Neyman–Pearson Lemma.     

Estimation of a relative potency of two preparations with correlated responses

Estimation of a relative potency of two preparations in so-called parallel-line assays is presented. A special type of incomplete Latin square designs where doses of preparations are administered is considered. Testing hypotheses about similarity of preparations and their relative potency in the case of correlated observations are regarded. Confidence interval for the relative potency of preparations is also given. Theoretical considerations are applied to point and interval estimation of potencies of new tuberculins with respect to some international standards tested in experiments on guinea-pigs.     

Double ASN Minimax sampling plans by variables when the standard deviation is unknown

We deal with the double sampling plans by variables proposed by Bowker and Goode (Sampling Inspection by Variables, McGraw–Hill, New York, 1952) when the standard deviation is unknown. Using the procedure for the calculation of the OC given by Krumbholz and Rohr (Allg. Stat. Arch. 90:233–251, 2006), we present an optimization algorithm allowing to determine the ASN Minimax plan. This plan, among all double plans satisfying the classical two-point-condition on the OC, has the minimal ASN maximum.     

Modified inference about the mean of the exponential distribution using moving extreme ranked set sampling

The maximum likelihood estimator (MLE) and the likelihood ratio test (LRT) will be considered for making inference about the scale parameter of the exponential distribution in case of moving extreme ranked set sampling (MERSS). The MLE and LRT can not be written in closed form. Therefore, a modification of the MLE using the technique suggested by Maharota and Nanda (Biometrika 61:601–606, 1974) will be considered and this modified estimator will be used to modify the LRT to get a test in closed form for testing a simple hypothesis against one sided alternatives. The same idea will be used to modify the most powerful test (MPT) for testing a simple hypothesis versus a simple hypothesis to get a test in closed form for testing a simple hypothesis against one sided alternatives. Then it appears that the modified estimator is a good competitor of the MLE and the modified tests are good competitors of the LRT using MERSS and simple random sampling (SRS).     

Integrated methodology for multiple systems estimation and record linkage using a missing data formulation

There are now three essentially separate literatures on the topics of multiple systems estimation, record linkage, and missing data. But in practice the three are intimately intertwined. For example, record linkage involving multiple data sources for human populations is often carried out with the expressed goal of developing a merged database for multiple system estimation (MSE). Similarly, one way to view both the record linkage and MSE problems is as ones involving the estimation of missing data. This presentation highlights the technical nature of these interrelationships and provides a preliminary effort at their integration.     

Using the Standardized Difference to Compare the Prevalence of a Binary Variable Between Two Groups in Observational Research

Researchers are increasingly using the standardized difference to compare the distribution of baseline covariates between treatment groups in observational studies. Standardized differences were initially developed in the context of comparing the mean of continuous variables between two groups. However, in medical research, many baseline covariates are dichotomous. In this article, we explore the utility and interpretation of the standardized difference for comparing the prevalence of dichotomous variables between two groups. We examined the relationship between the standardized difference, and the maximal difference in the prevalence of the binary variable between two groups, the relative risk relating the prevalence of the binary variable in one group compared to the prevalence in the other group, and the phi coefficient for measuring correlation between the treatment group and the binary variable. We found that a standardized difference of 10% (or 0.1) is equivalent to having a phi coefficient of 0.05 (indicating negligible correlation) for the correlation between treatment group and the binary variable.