The Scientific Misconduct Questionnaire—Revised (SMQ-R): Validation and Psychometric Testing

Purpose: The overall purposes of this article are to report the development of a survey instrument, Scientific Misconduct Questionnaire-Revised (SMQ-R) that elicits the perceptions of research coordinators managing clinical trials about the various aspects of scientific misconduct and to present the psychometric analyses for the SMQ-R.

Methods: A panel of five researchers and research coordinators reviewed the original SMQ (Rankin and Esteeves, 1997 Rankin, M. and Esteves, M. 1997. Perceptions of scientific misconduct in nursing. Nursing Research, 46(5): 270–276. [PUBMED][CSA][CROSSREF][Crossref] , [Google Scholar]) and suggested an additional 42 items based on the review of the literature and their own experiences in research. The SMQ-Revised (SMQ-R) consists of 68 closed-choice items in six sections and one section with 12 open-ended questions. The SMQ-R was sent to 5302 persons who were members of the Association for Clinical Research Professionals (ACRP) or subscribers to Research Practitioner, published by the Center for Clinical Research Practice (CCRP).

Findings: Internal consistency of subscales was assessed with Cronbach's alpha and ranged from .83 to .84. Confirmatory factor analysis was used to test construct validity of the instrument subscales. The factor structure was assessed with the principal factors method, using the squared multiple correlations as initial communality estimates followed by varimax (orthogonal) or biquartimax (oblique) rotations. Analyses revealed five distinct factors among three subscales. Construct validity for the SMQ-R was also assessed by testing hypothesized relationships using the known groups approach.

Conclusion: The current effort demonstrated the usefulness of the SMQ-R in obtaining information from a national sample of experienced research coordinators about their perceptions of the prevalence of different types of scientific misconduct and of factors that influence the occurrence of misconduct. The psychometric evaluation of the SMQ-R suggests good internal consistency for most subscales and suggests adequate construct validity of the instrument as a whole. The analyses also suggest that further refinement of the instrument for future studies is warranted.     

Weibull accelerated life tests when there are competing causes of failure

Accelerated life testing of a product under more severe than normal conditions is commonly used to reduce test time and costs. Data collected at such accelerated conditions are used to obtain estimates of the parameters of a stress translation function. This function is then used to make inference about the product's life under normal operating conditions. We consider the problem of accelerated life tests when the product of interest is a p component series system. Each of the components is assumed to have an independent Weibull time to failure distribution with different shape parameters and different scale parameters which are increasing functions stress. A general model i s used for the scale parameter includes the standard engineering models as special This model also has an appealing biological interpretation     

A class of tests for exponentiality against decreasing mean residual life alternatives

A class of tests is proposed for testing Exponentiality against the Decreasing Mean Residual Life (DMRL) class of non-exponential probability distributions. These tests are consistent and asymptotically unbiased against all continuous DMRL alternatives. They are U - statistics and hence asymptotically normally distributed. The asymptotic relative efficiency (ARE) with respect to other tests for DMRL are quite high. Small sample powers are also comparable with small sample powers of the competitors.     

Information Systems Management Issues: Reporting and Relevance*

Reports of key information systems issues have been published over the last two decades in many journals. Leading IS journals (e.g., MIS Quarterly, Information & Management, among others) have published key IS management issue reports every three or four years over the last 15 years, and will probably continue to provide such reports in the future. Although these reports claim to provide decisional guidance to practitioners, researchers, consultants, etc., the authors in their experience have noted concerns about their usefulness. While not questioning the validity of the methods and analysis conducted in these studies, we address two important questions in this article: the manner of reporting of the key issue results (which might be misleading), and the relevance of the results (are they providing what they intended to?). We hope that our discussion will provide new perspectives in making resource allocation decisions to both readers and authors of key issue articles.     

Cross-country disparities in skill premium and skill acquisition

Skilled individuals are rewarded more in poor than in rich countries. Why aren't more individuals acquiring skills in poor countries? We document that the unemployment rate of the skilled net of that of the unskilled decreases with a country's level of development. Using a matching model of occupational choice and skill acquisition, we quantify the role of barriers to enter entrepreneurship for these unemployment rates, skill premium and acquisition. The cross-country correlation between skill premium and acquisition decreases by 45% when each country's gap to the US in the entrepreneurship barrier is decreased enough to even the unemployment differential.