The social as signal in the body of chromatin

Human social interactions and material cultures are increasingly understood as biologically consequent environmental signals. Within the explanatory framework of epigenetics, such signals become biologically inscribed when transduced into bodies as persistent patterns of molecular conformation. In the life sciences, persistence of the social as the biological is understood as establishment of gene expression potentials, physiological changes, or epigenetic memories. How did the social become interchangeable with the environmental? When did both become scientifically graspable as signals? This article recounts the history of how hormone biologists came to think in terms of signal transduction in the late 1960s. This cybernetic legacy is important for understanding the ‘environmental turn’ of epigenetics. To understand the social as signal in the present moment – a post-cybernetic rather than post-genomic moment – the theory of the signal must itself be excavated and analysed.     

School‐to‐Work Transition of Career and Technical Education Graduates

This study analyzed the career development of career and technical education (CTE) high school graduates during their school‐to‐work transition, specifically their adaptability in the face of barriers. Forty graduates (22 men, 18 women) from working‐class backgrounds participated in baseline surveys at graduation and phenomenological interviews 1 year postgraduation. Primary themes were job loss altered career plans, whereas relevant jobs propelled career development; limited access to college constrained options, whereas college experience expanded options; graduates experienced the loss of education‐related support, and CTE served as a backup plan. Teachers and school counselors emphasized organizational barriers including limited staffing for upper level math courses and inconsistent workplace partnerships.     

Improving Africa's Roads: Modelling Infrastructure Investment and Its Effect on Sectoral Production Behaviour

Given the scarce resources for public investment in developing countries, policy analysis should include a detailed perspective on the effects of infrastructure. This article develops a modelling framework for analysing the effects of improved road infrastructure on the economy of African countries. The theoretical framework is tested empirically and used for simulations in a Computable General Equilibrium (CGE) model, and the effects on production and welfare are analysed. The model also serves to investigate the effect of roads on the economic participation of rural households.     

Healthy Barbs: Activism Confronts Mortality

Barbara Brenner, JD, was the Executive Director of Breast Cancer Action (BCA) from 1995–2010. Before that, she was a longtime activist in the anti-war movement and an attorney who, for most of her career, practiced public policy law. After she was diagnosed with breast cancer in 1993 at the age of 41, she took the helm of BCA. Under her leadership, the organization moved into a position of national advocacy—demanding research on the causes and prevention of breast cancer, including the role of industrial pollutants. Barbara started the “Think Before You Pink” campaign, encouraging people to question whether companies that display pink ribbons actually produce products that harm women's health or generate any funds to fight breast cancer. Her blog, “Healthy Barbs,” challenged readers to critique routine healthcare practices and policies. Barbara received numerous awards, including a Jefferson Award for Public Service in 2007, the Smith College Medal in 2012, and the ACLU-Northern California's Lola Hanzel Courageous Advocacy Award in 2012. Barbara had a recurrence of breast cancer in 1996. She died of complications associated with amyotrophic lateral sclerosis, ALS, on May 10, 2013.     

Constructing ‘disability’ in Myanmar: teachers,community stakeholders,and the complexity of disability models

This article explores Myanmar teachers’ and community stakeholders’ constructions of disability. We examine how various religious perspectives – particularly Buddhism – inform and shape understandings of impairment and how these beliefs intersect with a strongly medicalised construction of disability. However, in our discussion and exploration of the responses, we also found that the notion of two primary disability ‘models’ – namely the medical model and the social model – lack nuance, complexity, and socio-cultural consideration. Through examining teachers’ and community members’ perspectives of disability in Myanmar, we highlight the importance of socio-cultural variance in understanding local constructions of disability.     

Resolving complex community problems: Applying collective leadership and Kotter's change model to wicked problems within social system networks

How does collective leadership within social networks resolve chronic and complex problems common to communities? Unfortunately, sometimes it does not, but when it does, the outcome may be truly extraordinary. We use a case study approach to explain how one Midwest community within the USA applied collective leadership within a community network to reduce teen births. It took ten years of what many identified as provocative media campaigns and comprehensive sex education programs to reduce teen births by 65%, significantly exceeding the stated goal. Using Kotter's change model as a backdrop, powerful strategies and provocative creativity reveal courageous leadership within a social network of diverse people and organizations focused on improving the social well being of their community.     

The identification of distribution form II

The concept of distribution form developed in Brenner and Fraser (1980) is modified and extended to cover the more general context involving a class of distribution for form. This extension underlies the choice of a particular structural model for the three-parameter Weibull in Evans, Fraser and Massam (1982). The extended definition of distribution form is based on the requirement of objectivity in modelling (Fraser 1979). Three characterizations of this objectivity each require that the class of response presentations have closure under composition and thus be expressible in terms of a group. In particular, this implies that empirical support would not observationally be available for that generalization of a structural model called astructured model (Fraser 1972; the term functional model has been used inappropriately by Bunke, 1975 and Dawid and Stone, 1982).