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151.
This paper develops a likelihood‐based method for fitting additive models in the presence of measurement error. It formulates the additive model using the linear mixed model representation of penalized splines. In the presence of a structural measurement error model, the resulting likelihood involves intractable integrals, and a Monte Carlo expectation maximization strategy is developed for obtaining estimates. The method's performance is illustrated with a simulation study.  相似文献   
152.
Abstract Rural women have difficulty finding good jobs. Ownership of small businesses offers an alternative but the sales and income of women-owned firms are significantly lower than those of men-owned firms. Compared with men, women owners are more likely to operate smaller and newer businesses; however, these differences do not completely account for the gap in gross sales between men- and women-owned businesses. The strongest influences on business success are firm size, corporate status, and industrial sector. Though significant, the owner's gender is less important than these organizational characteristics. The factors influencing success of small businesses generally are the same for men- and women-owned businesses. More research on business networks and the start-up phase of small businesses is necessary for a better understanding of the sources of gender differences in success.  相似文献   
153.
Summary This paper solves some D-optimal design problems for certain Generalized Linear Models where the mean depends on two parameters and two explanatory variables. In all of the cases considered the support point of the optimal designs are found to be independent of the unknown parameters. While in some cases the optimal design measures are given by two points with equal weights, in others the support is given by three point with weights depending on the unknown parameters, hence the designs are locally optimal in general. Empirical results on the efficiency of the locally optimal designs are also given. Some of the designs found can also be used for planning D-optimal experiments for the normal linear model, where the mean must be positive. This research was carried out in part at University College, London as an M.Sc. project. Thanks are due to Prof. I. Ford (University of Glasgow) and Prof. A. Giovagnoli (University of Perugia) for their valuable suggestions and critical observations.  相似文献   
154.
该文从中国人口快速增长、经济建设加快、用水量逐年增大 ,加上气候变暖、少雨干旱将持续到 2 0 15年 ,我国北方水生态环境日趋恶化现状 ,说明在丰水区筑坝截流、调丰补歉势在必行 ,完全符合生态经济学发展原则和国际水法  相似文献   
155.
Formulae are provided that define the ‘bend points’, the beginning and end of the essentially linear dose–response region, for the four‐parameter logistic model. The formulae are expressed in both response and dose units. The derivation of the formulae is shown in order to illustrate the general nature of the methodology. Examples are given that describe how the formulae may be used while planning and conducting bioassays. Copyright © 2003 John Wiley & Sons, Ltd.  相似文献   
156.
In this article, we describe a straightforward method for solving the probability of at least one malignant cell by time t, and the associated hazard function, in the general (i.e., nonhomogeneous) two-stage Moolgavkar-Venzon-Knudson (MVK) model of cancer. The method consists of solving four coupled ordinary differential equations derived from the Kolmogorov backward equations for this process. The relationship of this method to previously proposed solutions is discussed.  相似文献   
157.
With the increasing pressure on social and health care resources,professionals have to be more explicit in their decision makingregarding the long-term care of older people. This groundedtheory study used 19 focus groups and nine semi-structured interviews(99 staff in total) to explore professional perspectives onthis decision making. Focus group participants and intervieweescomprised care managers, social workers, consultant geriatricians,general medical practitioners, community nurses, home care managers,occupational therapists and hospital discharge support staff.The emerging themes spanned context, clients, families and services.Decisions were often prompted by a crisis, hindering professionalsseeking to make a measured assessment. Fear of burglary andassault, and the willingness and availability of family to helpwere major factors in decisions about living at home. Serviceavailability in terms of public funding for community care,the availability of home care workers and workload pressureson primary care services influenced decision ‘thresholds’regarding admission to institutional care. Assessment toolsdesigned to assist decision making about the long-term careof older people need to take into account the critical aspectsof individual fears and motivation, family support and the availabilityof publicly funded services as well as functional and medicalneeds.  相似文献   
158.
Supporting processes of belonging in supervision and coachingThe contemporary employee has to cope with frequent changes. Not only does he lose his familiar environment, he also has to find ways to familiarize himself with new places and to develop a fresh sense of belonging. This process can be understood and facilitated by interpreting the German concept of “Heimat“ as something we have to create ourselves. First experiences demonstrate the usefulness of this approach in coaching processes.  相似文献   
159.
In this paper, the task of determining expected values of sample moments, where the sample members have been selected based on noisy information, is considered. This task is a recurring problem in the theory of evolution strategies. Exact expressions for expected values of sums of products of concomitants of selected order statistics are derived. Then, using Edgeworth and Cornish-Fisher approximations, explicit results that depend on coefficients that can be determined numerically are obtained. While the results are exact only for normal populations, it is shown experimentally that including skewness and kurtosis in the calculations can yield greatly improved results for other distributions.  相似文献   
160.
Summary The evaluation of the performance of seasonal adjustment procedures is an issue of practical importance in view of the unobservable nature of the components. Looking at just one indicator when judging the overall quality of a procedure may be misleading, even though this is common practice when many series are involved. The main purpose of this paper is to compare the information content of different synthetic indicators with reference to the X-11-ARIMA procedure. Sixty-six different types of monthly seasonal series are generated and the seasonal component then extracted by carrying out X-11-ARIMA with standard options. The correlation between the pseudo-true error for each series and various synthetic indicators allows us to compare the latter's reliability, under both the hypotheses of minimum and maximum variance of the pseudo-true seasonal component. We show that the overall quality indexQ-the indicator most commonly adopted by users of the X-11-ARIMA-is always outperformed by the simpler diagnostics based on the stability of the estimates. In particular, the “sliding-spans” indicator, proposed by Findley et al. (1990) and included in the diagnostics of the new X-12 procedure, shows a much stronger correlation with the pseudo-true error in the seasonal adjustment. We also show that the total forecasting errors in the one-year-ahead extrapolation of the seasonal component have a good informative power and perform almost as well as the “sliding-spans” indicator.  相似文献   
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