Adaptative Designs for Multi-Arm Clinical Trials: The Play-the-Winner Rule Revisited

Adaptative designs for clinical trials that are based on a generalization of the “play-the-winner” rule are considered as an alternative to previously developed models. Theoretical and numerical results show that these designs perform better for the usual criteria. Bayesian methods are proposed for the statistical analysis of these designs.     

A Method for Simulating Multivariate Non Normal Distributions with Specified Standardized Cumulants and Intraclass Correlation Coefficients

Intraclass correlation coefficients (ICCs) are commonly used indices in subject areas such as biometrics, longitudinal data analysis, measurement theory, quality control, and survey research. The properties of the ICCs most often used are derived under the assumption of normality. However, real-world data often violate the normality assumption. In view of this, a computationally efficient procedure is developed for simulating multivariate non normal continuous distributions with specified (a) standardized cumulants, (b) Pearson intercorrelations, and (c) ICCs. The linear model specified is a two-factor design with either fixed or random effects. A numerical example is worked and the results of a Monte Carlo simulation are provided to demonstrate and confirm the methodology.     

Risk Perception and Personality Facets

The present study examined the relationship between personality facets and risk perception using the Big Five model. A broad range of hazards was considered: energy production, pollutants, sex, deviance, addictions, weapons, common individual hazards, outdoor activities, medical care, and psychotropic drugs. Key personality facets that were most predictive of risk perception compared to (or in association with) age, gender, educational level, and personality factors were identified. They were moderation and tranquility (associated with energy production or pollutants), rationality and efficiency (associated with pollutants, sex, deviance, addictions, or weapons), creativity, imagination, and reflection (associated with energy production, pollutants, or common individual hazards), self-disclosure (associated with outdoor activities), and nurturance and tenderness (associated with sex, deviance, addictions, or medical care). These facets may be recommended for use in future studies on risk perception.     

Cognition and Behavior in Normal‐Form Games: An Experimental Study

This paper reports experiments designed to study strategic sophistication, the extent to which behavior in games reflects attempts to predict others’ decisions, taking their incentives into account. We study subjects’ initial responses to normal‐form games with various patterns of iterated dominance and unique pure‐strategy equilibria without dominance, using a computer interface that allowed them to search for hidden payoff information, while recording their searches. Monitoring subjects’ information searches along with their decisions allows us to better understand how their decisions are determined, and subjects’ deviations from the search patterns suggested by equilibrium analysis help to predict their deviations from equilibrium decisions.     

Covid and Public Funds: More Opportunities for a Misuse? The Case of the Intermediate Governments of Galicia

Public Organization Review - Corruption and inefficiency of public funds pose a risk in public administrations. This paper analyses the corruption risk at the local level by analysing indicators of...     

The Management of Redundancies in Europe: The Case of Denmark

The paper presents the findings of comparative and interdisciplinary legal and economic study on managing labour redundancies in seven EU member countries. It is structured for comparability between the systems examined. The introductory section contains an account of the evolution of the Danish labour market, with special reference to redundancy trends, of the features of the programmes for managing redundancies, of the roles of firms and the ‘external environment’ in handling workforce adjustments. The second section presents a map of policies that work to prevent labour redundancies (preventive measures) such as flexibility, training etc. Next, the instruments for handling temporary labour redundancies (retentive measures) are examined (e.g. short-time working, temporary layoffs etc.). The following section is devoted to instruments and programmes involved in the management of permanent labour redundancies (expulsive measures), e.g. collective dismissals, severance pay etc. The final section provides an overall assessment of the Danish system for managing labour redundancies, and briefly discusses the national debate on the prospects for reform, in light of the principles and policies of convergence set forth by the European Union.     

The Process of Job Creation and Job Destruction in the Italian Economy

ABSTRACT: Longitudinal analysis of labour flows provides a number of important indications on the characteristics of job creation and job destruction in the Italian economy, and on the role played by small firms in this process. The main indications may be summarized as follows: 1)the ratio of total separations to total work-force is remarkably high, and almost completely independent of the business cycle: one out of four workers leaves his/her position each year in the economy at large. In the small firms sector alone turnover is much higher, with total separations almost approaching 50|X% of employment; 2)as the economy takes a downturn, it is mainly the number of jobs created through expansion of existing firms that follows this cycle, while separations remain roughly constant; 3)the proportion of jobs created via the establishment of new firms is modest compared to that attributable to the expansion of existing plants (16.0-14.491)). Likewise, the proportion of job losses due to closures visi vis employment shedding by contracting firms, is of the same order of magnitude; 4)job creation and destruction is very high in the small firm sector. Employment in firms of dimension (0-19) is 25.8 % of total employment at the beginning of the observation period (1978) and reaches 28% at its end (1984). Yet the proportion of job creation attributable to small firms is approximately 60% of the new positions due to expansion of existing firms in manufacturing, and 68% in the services. The fraction of jobs destroyed by small firms is somewhat lower: about 46% in manufacturing and 59% in the services; 5)he small firms contribution to net job creation appears even more remarkable both in the aggregate, as well as within all sectors of economic activity and geographical areas. In 1978-80 net employment change in manufacturing is 106,000 units per year; correspondingly net job creation by firms (0-19) is alone 222,000. In the services the proportion between net employment change and the share of the small firms is 1:3. In 1981-83, while in manufacturing over 213,000 jobs are destroyed on average each year, net creation by small firms is still positive (+ 48,000); in the services the overall change is very small (+ 3,000), while the net contribution of small firms is + 53,000.     

Entreprise Management in the USSR: is there a Productivity Drive?*

Abstract. According to some neo-institutional economists, the trade-off of perestroika is between the benefits of solving economic problems via institutional changes and the costs of upsetting the nomenklatura. The “sub-institutional” analysis shows instead a series of organizational adjustments of the productive system that can render this dilemma less pressing, provide Western financial aid increases. This aid will ease the social and political tensions of the transition much more than helping the start of a productivity drive in Soviet firms.