The efficacy and safety of short-acting testosterone ointment (Glowmin) for late-onset hypogonadism in accordance with testosterone circadian rhythm

Introduction: It is well known that there is a reduction of circadian rhythm in blood testosterone levels with aging. Our previous report revealed that 3?mg of short-acting testosterone ointment (Glowmin: GL) elevated serum testosterone levels to within the physiological range for 4–6?h. The aim of this study was to clarify the clinical efficacy and safety of GL used topically once every morning, to enhance the circadian rhythm of testosterone, for late-onset hypogonadism (LOH).

Methods: A total of 61 LOH patients received 3?mg of GL topically once a day in the morning on scrotal skin for 24 weeks. The clinical efficacy of GL was evaluated by the aging males symptoms (AMS) scale, and blood sampling tests were measured before and after GL treatment.

Results: Mean patients age was 55.3?±?9.2 years old. Total AMS scores at 4, 12, and 24 weeks after GL treatments significantly decreased. The results of sub-analysis of AMS, including psychological, physical, and sexual factors also significantly improved after GL treatments. No severe adverse reactions or abnormal laboratory data were reported.

Conclusions: This study shows that TRT for LOH with once daily GL treatment supports testosterone circadian rhythm and should be considered to be an effective and safe therapy for LOH.     

Examining links between cocaine use and street‐based sex work in New South Wales,Australia

We examined potential links between cocaine use and street‐based sex work in New South Wales, Australia, following reports of increased cocaine use among injection drug users (IDU). Police data on prostitution and possession/use of cocaine was analysed using time series analysis. Interviews with key informants and IDU were also conducted, and data on cocaine use from ongoing monitoring systems targeted at IDU were analyzed. There was a clear increase in cocaine use among IDU which occurred in 2001. This occurred at the same time as an increase in prostitution offenses. Qualitative data suggested a greater number of primary heroin users were engaging in street‐based sex work, which was driven in part by the increases in cocaine use among this group. Subsequent reductions in cocaine availability led to decreased cocaine use and possession offenses, along with reductions in prostitution offenses.     

From Codes to Contextual Collaborations: Shifting the Thinking About Ethics in Social Work

In this article, the authors argue that the current emphases in social work on codes, standards, and decision-making models are insufficient to the task of ensuring ethical relationships between workers and clients. Three fundamental assumptions that underpin codes and standards are analyzed. The authors then explore the nature of ethical relationships and demonstrate how codes and standards, in their current form, do not address the complexity and contextuality of the social work relationship. After considering why the profession relies so heavily on codes and standards, they call for a re-thinking of ethical relationships, offering ideas and recommendations for those relationships.     

Policy Planning Models: Heuristics for Education

Findings from a study of 229 students at five schools of social work in the introductory research course show: students with a good background in research learn best when a variety of content is introduced; students with poor backgrounds gain most with limited content. All students appear to learn best when taught by didactic methods and evaluated by objective examinations as compared to other methods. Differences in teacher characteristics such as age, field of study, and experience had little impact on student learning.     

Couple age discrepancy and risk of intimate partner homicide

Although national level studies in the United States and Canada find that extreme partner age discrepancy is a risk factor for intimate partner homicide in opposite-sex couples, these studies carry two caveats: They are limited to cohabiting marital or common-law couples and they are not detailed enough to explore alternative explanations for the age discrepancy-homicide risk association. Using the Chicago Homicide Dataset, which includes all homicides that occurred in Chicago from 1965 to 1996, we analyze the 2,577 homicides in which the victim was killed by a current or former legal spouse, common-law spouse, or heterosexual boyfriend or girlfriend, and in which the woman was at least 18 years of age. Within each of 14 categories of couple age discrepancy, we estimate the population of intimate heterosexual couples and calculate the population-based risk of homicide. The results replicate national level findings showing that the risk of intimate partner homicide is considerably elevated for couples with a large discrepancy between their ages-where the man is at least 16 years older than the woman or the woman is at least 10 years older than the man. This risk pattern occurs regardless of whether the man or the woman was the homicide offender. We then investigate whether the link between partner age discrepancy and homicide risk is explained by the offender's arrest record. Results show that the higher risk of intimate partner homicide for age discrepant couples is robust, and does not depend on the previous arrest record of the offender. Discussion addresses other possible explanations for the increased risk of partner homicide for age discrepant couples, and the practical implications of these findings.     

Recruitment,enrollment & data collection with victims of elder abuse and neglect identified from police incident reports

ABSTRACT

This study evaluated the success of researcher-generated recruitment, enrollment, data collection, and safety protocols for field research with victims of elder abuse and neglect (EAN) identified from police incident reports in terms of their success including cost-effectiveness, ability to generate a representative sample, and safety. After reviewing 492 police incident reports involving victims age 65 years or older to identify cases of EAN 62 victims were identified. Mail, phone, and in-person recruitment strategies were used. After 259 recruitment attempts, 52 (84%) eligible victims were contacted, of which 24 (46%) consented to participate. Phone calls were the least expensive mechanism to produce a successfully enrolled participant. Findings from a regression show completion of a research interview could not be predicted by victim, suspect, or offense characteristics, indicating that the recruited victims likely represent the population they were drawn from. No safety or adverse events occurred.