Estimand framework: Are we asking the right questions? A case study in the solid tumor setting

The estimand framework requires a precise definition of the clinical question of interest (the estimand) as different ways of accounting for “intercurrent” events post randomization may result in different scientific questions. The initiation of subsequent therapy is common in oncology clinical trials and is considered an intercurrent event if the start of such therapy occurs prior to a recurrence or progression event. Three possible ways to account for this intercurrent event in the analysis are to censor at initiation, consider recurrence or progression events (including death) that occur before and after the initiation of subsequent therapy, or consider the start of subsequent therapy as an event in and of itself. The new estimand framework clarifies that these analyses address different questions (“does the drug delay recurrence if no patient had received subsequent therapy?” vs “does the drug delay recurrence with or without subsequent therapy?” vs “does the drug delay recurrence or start of subsequent therapy?”). The framework facilitates discussions during clinical trial planning and design to ensure alignment between the key question of interest, the analysis, and interpretation. This article is a result of a cross-industry collaboration to connect the International Council for Harmonisation E9 addendum concepts to applications. Data from previously reported randomized phase 3 studies in the renal cell carcinoma setting are used to consider common intercurrent events in solid tumor studies, and to illustrate different scientific questions and the consequences of the estimand choice for study design, data collection, analysis, and interpretation.     

An examination of attachment representations among child welfare professionals

Research has documented a relationship between adult attachment representations and client relationships and outcomes for professionals in relationship-based fields (e.g., , , , , ,  and ), but has not examined the child welfare professionals specifically. The current study examined attachment representations of 54 child welfare professionals. The Adult Attachment Interview (AAI) was administered to participants prior to attending a professional workshop. Results indicated significant differences between the AAI distribution of child welfare professionals and a non-clinical norm sample (AAI four-way distribution: Goodness of fit χ² = 23.63, p < .01; Bakermans-Kranenburg & van IJzendoorn, 2009). Dismissing classifications were overrepresented and free-autonomous classifications were underrepresented. Results may indicate challenges in the child welfare system that could alter the effectiveness and decision-making processes of child welfare professionals. Further research is needed to evaluate whether these differences are typical for samples of child welfare professionals and if so, the impact it could have on families who are being served. Effective interventions, focused on shifting attachment from insecure to secure, for child welfare professionals also should be explored through further research.     

Exploring racial identities through participatory visual and ethnographic methods: (Re)presenting the identities of ethnic minority youth in Hong Kong

There is increasing research attention to the integration of ethnic minority youth in Hong Kong. Within this attention lies an interest in how these young people make sense of their identities in relation to their schooling experiences. From a qualitative methodological viewpoint, researchers’ positionalities, including their cultural background and scholarly motivations, have implications on the ways in which they (re)present their findings. Using the axes of insider and outsider, we reflect on and compare how we have approached two studies with ethnic minority youth in Hong Kong. We discuss the potential affordances and tensions of cultural insider and outsider roles in our research to highlight the cultural dynamics in our interactions with our participants. As we advance dialogue on how researchers approach their work through their own cultural positionalities, we offer a nuanced account of the complexities surrounding the ‘making’ of ethnic minority young people’s identities in Hong Kong.     

Conservation technology adoption decisions and the theory of planned behavior

This study of water saving technology adoption and technology investment behavior for Florida strawberry farmers represents an application of the Theory of Planned Behavior. It is compared with the Theory of Reasoned Action, and the Theory of Derived Demand. The focus is on perceived control in the decisions, first, to become an adopter of conservation technology, and, second, to invest more capital in the technology. The results lend credence to the Planned Behavior Theory but also support Derived Demand Theory, in that actual financial capability (actual control) is found important. To predict technology adoption we may need to account for both perceived and actual control. Unfettered government control of farmer technology decisions could be counterproductive, suggesting technology policy may need to include a mix of moral suasion and incentives with more modest controls.     

A Movement’s Legacy: Southern Echo and the Continued Struggle for Racial Justice in the Delta

Recent research has complicated popular understandings of the civil rights movement, calling into question its timeline, key players, and biggest victories. Scholars have highlighted the role of community organizing, arguing that capacity-building and leadership development were the movement’s real wins. Yet little research has examined how contemporary organizers view and use this history in their current work. Drawing upon interview and observational data from a qualitative case study, this article explores how one Delta organization, Southern Echo, responds to the movement of the 1950s and 1960s in its organizing today. We argue that Echo organizers and leaders see the civil rights movement as an ongoing struggle, and we show that Echo adopts a critical stance in analyzing past civil rights work; Echo’s structure and strategies are a direct response to this history. Our analysis offers a new, critical perspective to understandings of the civil rights movement.     

Sociological Perspectives on Japanese Manga in America

Japanese popular culture has, according to journalist Roland Kelts, “invaded” the United States in the 21st century, and in particular Japanese comics, known as manga, have successfully “conquered America,” according to Wired magazine. Within the publishing trade itself, the medium's cultural and commercial success became known as the “manga revolution” or the “manga boom.” Yet despite all of this excitable rhetoric, there has thus far been scant sociological research into the particularities of this emerging phenomenon, and what exists is widely dispersed across multiple humanities and social science disciplines. This essay therefore aims to unite this scattered literature and provide a comprehensive survey of sociological perspectives on Japanese manga in America. I identify and explore three main substantive trends in the scholarly discourse: (i) studies of gender and sexuality and the homoerotic manga genres known as boys' love or yaoi; (ii) intellectual property, copyright, and the global digital piracy of manga colloquially known as “scanlation”; and (iii) studies of cultural production and the political economy of the American manga industry. This essay concludes with a discussion of the limitations these perspectives have in common and suggests a more critical research program drawing upon an expanded theoretical toolkit.