NOS3基因与阿尔茨海默病患病风险关联的研究

目的：阿尔茨海默病（ AD）是最常见的神经退行性疾病,与基因的多态性有关,包括内皮一氧化氮合酶3（ NOS3）发生变化。 NOS分解一氧化氮,并且在血脑屏障中起到有关键作用。探索NOS3基因（ rs1799983,G）与中国南方人群阿尔茨海默病患病风险的关联。方法采用病例-对照研究,在74例散发性患者和139例对照者中,对NOS3基因（rs1799983, G）进行两组间的等位基因及遗传模型基因型差异分析,NOS3基因使用聚合酶连反应-限制性内切酶（ PCR-RFLP）方法分型并测序进行验证。结果①NOS3基因（rs1799983,G）风险等位基因和基因型的频率在病例组和对照间组间的分布无显著性差异（P＞0.05）。②NOS3基因（rs1799983,G）在AD患者中携带ApoE4与非携带ApoEε4两组间基因型频率无显著性差异。结论研究显示NOS3基因rs1799983,G可能与中国南方人群AD患病风险无关联。     

参与式扶贫中政府与农户合作的障碍与对策

参与式扶贫模式虽涌现出一些成功典范,但贫困人口的参与绝不是包治百病的灵丹妙药,其间有诸多障碍和问题需分析、解决.现阶段,中国大规模推广参与式扶贫的政治社会环境和贫困人口自身的小环境尚不具备,只有政府和农户合理分权、分工,密切合作,扬长避短,才能实现扶贫开发的效益最大化.     

Developing From Tranditional Microscale Chemistry to Microscale Green Chemistry

Microscale chemistry is appealing to all levels of education.In contrast to conventional macroscale chemistry,only minute amount of chemicals are required to undertaking a chemical investigation.     

D-optimal design for a quadratic log contrast model for experiments with mixtures

A practical method is suggested for solving complicated D-optimal design problems analytically. Using this method the author has solved the problem for a quadratic log contrast model for experiments with mixtures introduced by J. Aitchison and J. Bacon-Shone. It is found that for a symmetric subspace of the finite dimensional simplex, the vertices and the centroid of this subspace are the only possible support points for a D-optimal design. The weights that must be assigned to these support points contain irrational numbers and are constrained by a system of three simultaneous linear equations, except for the special cases of 1- and 2-dimensional simplexes where the situation is much simpler. Numerical values for the solution are given up to the 19-dimensional simplex     

礼物的话语:春节场域下送礼演绎模式的文化解读

礼物交换充斥于人们生活的始终,是司空见惯的现象.并且,在春节这样一个超常规的时空中,它更成为具有丰富文化内涵的特殊社会现象.礼物运行在春节期间强化着村民的特殊权利义务时空.通过调查访谈,了解春节期间礼物交换的种种现象,对礼物的社会生命进行现象学归纳、符号学解读,试图从文化社会学的视角去剖析春节送礼的独特话语系统,并对春节送礼传统的现代化走向作了相关探索.     

再论乡约价值的多维消解和理性重整

面对乡约的人类价值、文化民族价值、教化价值、自治价值、制度价值、组织价值等的多元消解趋势,在当前农村法治实践视阙下,以乡村社会制度的公平配置重整乡约价值意义重大.新型乡约价值评判标准在于将法理内化为人们的行为习惯,让村民过上"诗意的栖居"的理想生活,从伦理社会走向法理社会.     

On the adjudication of conflicting claims: an experimental study

This paper reports an experimental study on three well-known solutions for problems of adjudicating conflicting claims: the constrained equal awards, the proportional, and the constrained equal losses rules. We first let subjects play three games designed such that the unique equilibrium allocation coincides with the recommendation of one of these three rules. In addition, we let subjects play an additional game that has the property that all (and only) strategy profiles in which players coordinate on the same rule constitute a strict Nash equilibrium. While in the first three games subjects’ play easily converges to the unique equilibrium rule, in the last game the proportional rule overwhelmingly prevails as a coordination device, especially when we frame the game as an hypothetical bankruptcy situation. We also administered a questionnaire to a different group of students, asking them to act as impartial arbitrators to solve (among others) the same problems played in the lab. Also in this case, respondents were sensitive to the framing of the questions, but the proportional rule was selected by the vast majority of respondents.     

奥巴马访印对中印美三角关系的影响

2010年11月,美国总统奥巴马对印度进行了里程碑式的访问,将印美关系提升到空前的高度。奥巴马首访印度受到了多方面的关注,国内外学界普遍认为印美之间的接触暗含中国因素。本文将重点分析中印美三角关系的发展变化,论述导致印美之间接近的利益诉求,评估印美结盟对抗中国的可能性,并提出相应的对策建议。     

A new estimator of entropy

Vasicek (1976) proposed an estimator of entropy based on spacings. A new estimator of entropy is proposed. This new estimator is based on local linear regression. Comparisons between this new estimator and Vasicek's estimator are made. The mean square error (MSE) of the new estimator is consistently smaller than the MSE of Vasicek's estimator.     

Communicative competence and the facilitating and perturbing factors in the socialisation of immigrant students

This work analyses the communicative competence and the factors that facilitate and perturb the socialisation of immigrant students in primary education. It provides greater knowledge concerning the relationship between the immigrant student's social and linguistic competence. It also analyses the presence of difficulties in the different language components (morphology, syntax, semantics and pragmatics). The sample is made up of a total of 326 immigrant students between 6 and 12 years of age, attending 10 different schools. The study demonstrates that immigrant students possess a low level of linguistic dominion. All the linguistic components analysed are affected, although greater difficulties are evident in morphology and syntax than in semantics and pragmatics. The relationship between linguistic competence and the factors that facilitate and perturb socialisation is underlined. This work concludes that there is a significant relation between semantics and pragmatics and several socialisation factors (leadership, aggressiveness–stubbornness and anxiety–shyness). The educational centres should be aware of the complicated learning process that immigrant students have to go through.