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Charles W. Griffiths Chris Dockins Nicole Owens Nathalie B. Simon Daniel A. Axelrad 《Risk analysis》2002,22(4):679-688
To quantify the health benefits of environmental policies, economists generally require estimates of the reduced probability of illness or death. For policies that reduce exposure to carcinogenic substances, these estimates traditionally have been obtained through the linear extrapolation of experimental dose-response data to low-exposure scenarios as described in the U.S. Environmental Protection Agency's Guidelines for Carcinogen Risk Assessment (1986). In response to evolving scientific knowledge, EPA proposed revisions to the guidelines in 1996. Under the proposed revisions, dose-response relationships would not be estimated for carcinogens thought to exhibit nonlinear modes of action. Such a change in cancer-risk assessment methods and outputs will likely have serious consequences for how benefit-cost analyses of policies aimed at reducing cancer risks are conducted. Any tendency for reduced quantification of effects in environmental risk assessments, such as those contemplated in the revisions to EPA's cancer-risk assessment guidelines, impedes the ability of economic analysts to respond to increasing calls for benefit-cost analysis. This article examines the implications for benefit-cost analysis of carcinogenic exposures of the proposed changes to the 1986 Guidelines and proposes an approach for bounding dose-response relationships when no biologically based models are available. In spite of the more limited quantitative information provided in a carcinogen risk assessment under the proposed revisions to the guidelines, we argue that reasonable bounds on dose-response relationships can be estimated for low-level exposures to nonlinear carcinogens. This approach yields estimates of reduced illness for use in a benefit-cost analysis while incorporating evidence of nonlinearities in the dose-response relationship. As an illustration, the bounding approach is applied to the case of chloroform exposure. 相似文献
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Chris Dockins Robin R Jenkins Nicole Owens Nathalie B Simon Lanelle Bembenek Wiggins 《Risk analysis》2002,22(2):335-346
This article explores two problems analysts face in determining how to estimate values for children's health and safety risk reductions. The first addresses the question: Do willingness‐to‐pay estimates for health risk changes differ across children and adults and, if so, how? To answer this question, the article first examines the potential effects of age and risk preferences on willingness to pay. A summary of the literature reporting empirical evidence of differences between willingness to pay for adult health and safety risk reductions and willingness to pay for health and safety risk reductions in children is also provided. The second dimension of the problem is a more fundamental issue: Whose perspective is relevant when valuing children's health effects—society's, children's, adults‐as‐children, or parents'? Each perspective is considered, followed ultimately by the conclusion that adopting a parental perspective through an intrahousehold allocation model seems closest to meeting the needs of the estimation problem at hand. A policy example in which the choice of perspective affects the outcome of a regulatory benefit‐cost analysis rounds out the article and emphasizes the importance of perspective. 相似文献
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Natural and social order at Walt Disney World; the functions and contradictions of civilising nature
Chris Wright 《The Sociological review》2006,54(2):303-317
Elias’ theory of the civilising process is used to show how the Walt Disney World Theme Parks construct social control over visitors without calling into question the official presentation of these visitors as free, choice‐making, experience seeking individuals. Particular attention is drawn to the manipulation of images of nature as either ‘wild’ or ‘civilised’ to code, respectively, forbidden and legitimate places for visitors. In doing so, WDW is able to maintain civilised, non‐coercive, discourse with its ‘guests’ who are, thus presented to themselves as responsible and self‐regulating persons. Attention is drawn to the contradiction that this strategy creates between ‘authentic’ and ‘civilised’ spectacle particularly in the presentation of animals. It is noted how this creates an imperative to show only civilised animal behaviour but which, in turn, limits the means that the Disney Corporation can adopt in order to create a space that is free from the intrusion of uncivilised nature. 相似文献
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Many thousands of people in developing country cities depend on recycling materials from waste for their livelihoods. With the focus of the Millennium Development Goals on poverty reduction, and of waste strategies on improving recycling rates, one of the major challenges in solid waste management in developing countries is how best to work with this informal sector to improve their livelihoods, working conditions and efficiency in recycling.The general characteristics of informal recycling are reviewed, highlighting both positive and negative aspects. Despite the health and social problems associated with informal recycling, it provides significant economic benefits that need to be retained. Experience shows that it can be highly counterproductive to establish new formal waste recycling systems without taking into account informal systems that already exist. The preferred option is to integrate the informal sector into waste management planning, building on their practices and experience, while working to improve efficiency and the living and working conditions of those involved. Issues associated with integrating informal recycling into the formal waste management sector are discussed. 相似文献
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Rosa Arboretti Riccardo Ceccato Luca Pegoraro Luigi Salmaso Chris Housmekerides Luca Spadoni Elisabetta Pierangelo Sara Quaggia Catherine Tveit Sebastiano Vianello 《Journal of applied statistics》2022,49(10):2674
Industrial statistics plays a major role in the areas of both quality management and innovation. However, existing methodologies must be integrated with the latest tools from the field of Artificial Intelligence. To this end, a background on the joint application of Design of Experiments (DOE) and Machine Learning (ML) methodologies in industrial settings is presented here, along with a case study from the chemical industry. A DOE study is used to collect data, and two ML models are applied to predict responses which performance show an advantage over the traditional modeling approach. Emphasis is placed on causal investigation and quantification of prediction uncertainty, as these are crucial for an assessment of the goodness and robustness of the models developed. Within the scope of the case study, the models learned can be implemented in a semi-automatic system that can assist practitioners who are inexperienced in data analysis in the process of new product development. 相似文献
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Chris Tapp 《Significance》2007,4(2):71-73
The average household in the UK is in debt to the tune of nearly £9000—and that is not including the mortgage. Consumer borrowing, on credit cards, car and retail finance deals, overdrafts and unsecured personal loans was £4525 per average UK adult at the end of February 2007. Are we drowning in debt? Chris Tapp , Associate Director of Credit Action, reports. 相似文献