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排序方式: 共有638条查询结果,搜索用时 15 毫秒
631.
This paper investigates how planning experts understand the potential of integrating the concept of green infrastructure in planning practice in Germany. It develops a systematic approach for green infrastructure planning at the landscape scale. Research methods include a web-based survey among German planning experts and geographic information system analysis in the case study region of Hannover. Survey results suggest that the green infrastructure concept is not yet well known in planning practice, and that the potential benefits for planning lie primarily in communication purposes. An approach is developed here that sets priorities for green infrastructure development based on its potentials for creating synergies in the provision of ecosystem services.  相似文献   
632.
Luxury, historically an exclusive, rare and elitist phenomenon, is changing. This is predominantly driven by technological developments, particularly social media, and the rising level of consumer empowerment in the marketplace. A maturing stream of research has emerged assessing the effects of social media platforms on luxury brands, offerings and consumers. However, there has been no comprehensive analysis of this extant literature synthesizing the current state of knowledge and postulating future research directions. This paper addresses this gap by utilizing a systematic literature review approach. A total of 115 articles were collected and analysed and five core themes were identified, examining (1) luxury brand strategy, (2) luxury brand social media communications, (3) luxury consumer attitudes and perceptions, (4) engagement and (5) social media's influence on brand performance-related outcomes. These themes are comprehensively explored to understand the myriad impacts of social media on luxury businesses before conceptualizing the themes as a holistic framework explaining social media's role within luxury. The framework developed highlights the fragmented yet progressive nature of research on the confluence of social media and luxury, and signals fruitful avenues for further inquiry. It is proposed that scholarly attention is directed towards multiple lines of inquiry, including social media's role in luxury brand construction online, social media's role in facilitating ‘moments of luxury’, younger consumers’ luxury consumption, as well as the integration of both future innovative technological developments and novel social media platforms within luxury branding.  相似文献   
633.
Sponsors have a responsibility to minimise risk to participants in clinical studies through safety monitoring. The FDA Final Rule for IND Safety Reporting requires routine aggregate safety evaluation, including in ongoing blinded studies. We are interested in estimating the probability that the true adverse event rate in the experimental arm exceeds that in the control arm. We developed a Bayesian approach that specifies an informative meta-analytic predictive prior on the event probability in the control arm and an uninformative prior on that in the experimental arm. We combined these priors with a mixture likelihood that considers each patient in the ongoing blinded study may belong to the experimental or control arm. This allowed us to estimate the quantity of interest without unblinding. We evaluated our method by simulation, pairing scenarios that differed only in whether a safety signal was present or missing, and quantifying the ability of our model to discriminate using signal detection theory. Our approach shows benefit. It detects safety signals more reliably with greater sample sizes and for common rather than rare events. Performance does not deteriorate markedly when historical studies exhibit heterogeneous hazards or non-constant hazards. Our method will allow us to monitor safety signals in ongoing blinded studies with the goal of earlier identification and risk mitigation. Our method could be adapted to use informative priors on both arms or predictive covariates where pertinent data exist. We stress that ongoing safety monitoring should involve a multi-disciplinary team where statistical methods are paired with medical judgement.  相似文献   
634.
Engaging with music fosters prosocial responding in infants and toddlers. In this pilot study, we examined whether music that expresses contrasting emotions (happy vs. sad) was associated with toddlers’ helpfulness. Seventy-five 18-month-olds from Hong Kong China were randomly assigned to engage with music with an experimenter in one of two conditions: happy- or sad-sounding music. After the musical engagement task, toddlers from both conditions completed the same set of helping tasks. For instrumental (action-based) helping, toddlers were significantly more helpful after engaging with happy-sounding music than with sad-sounding music. Our initial findings suggest that cues linked to happy- and sad-sounding music influence toddlers’ prosocial responses.  相似文献   
635.
This is a qualitative study of Black cisgender women's faculty experiences using an interactionist framework. Relying on in-depth interviews, we explore the experiences of eight Black, cisgender, women, sociology faculty across the United States in various tenure and non-tenure roles at different institutions (community college, teaching college, and research universities). Participants engaged in a variety of impression management techniques to overcome implicit biases and controlling images that shaped their students', and their colleagues', perceptions. While women in our study had agency, they were limited in the ways they could present themselves, a phenomenon Deil-Amen and Tevis describe as circumscribed agency. Once women in our study had achieved seniority they were able to express themselves in culturally authentic ways. Theoretically, this study shows how interpretive sociology can overcome its theoretical limitations in dealing with race, and shows that the interactionist perspective is actually well suited towards discussing this matters in a meaningful way. We conclude by advocating for greater awareness surrounding the lived experience of Black, women faculty, especially by those who mentor and evaluate them.  相似文献   
636.
The addendum of the ICH E9 guideline on the statistical principles for clinical trials introduced the estimand framework. The framework is designed to strengthen the dialog between different stakeholders, to introduce greater clarity in the clinical trial objectives and to provide alignment between the estimand and statistical analysis. Estimand framework related publications thus far have mainly focused on randomized clinical trials. The intention of the Early Development Estimand Nexus (EDEN), a task force of the cross-industry Oncology Estimand Working Group ( www.oncoestimand.org ), is to apply it to single arms Phase 1b or Phase 2 trials designed to detect a treatment-related efficacy signal, typically measured by objective response rate. Key recommendations regarding the estimand attributes include that in a single arm early clinical trial, the treatment attribute should start when the first dose is received by the participant. Focusing on the estimation of an absolute effect, the population-level summary measure should reflect only the property used for the estimation. Another major component introduced in the ICH E9 addendum is the definition of intercurrent events and the associated possible ways to handle them. Different strategies reflect different clinical questions of interest that can be answered based on the journeys an individual subject can take during a trial. We provide detailed strategy recommendations for intercurrent events typically seen in early-stage oncology. We highlight where implicit assumptions should be made transparent as whenever follow-up is suspended, a while-on-treatment strategy is implied.  相似文献   
637.
The goal of the current study was to investigate the contribution of both trait-like individual differences and dyadic processes to the content of children's conversations. Fifty-two groups typically consisting of four same-sex unfamiliar nine-year-old children (N = 202) interacted in all possible dyads, resulting in six dyads per group. Each dyad completed a 5-min frustration task and a 5-min planning task. Observers coded children's verbalizations into 10 categories and further summed these categories into prosocial (suggest, agree, solicit input, ask, encourage, state personal) and antisocial (command, disagree, discourage, aggress) verbalizations, resulting in 24 variables (12 per task). Across both tasks, Social Relations Model analyses provided evidence of the role of both individual differences [significant effects for actor variance (15 of 24 variables), actor-actor correlations, and intrapersonal correlations] and dyadic processes [significant effects for partner variance (4 of 24 variables), relationship variance (18 of 24 variables), dyadic reciprocity correlations (10 of 24 variables), and interpersonal correlations] in children's conversations with peers.  相似文献   
638.
VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - In this article we show the potential of using documents to answer research questions pertinent to nonprofit and voluntary...  相似文献   
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