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181.
Epigenetics has considerable potential to transform social science by embedding mutually regulative reciprocal connections between biological and social processes within the human activities it studies. This paper highlights common epigenetic methods and outlines practical considerations in the design of ‘social epigenetics’ research addressing the identification of biomolecular pathways, statistical inference of causality, conceptualization of the environment as a biochemical event, heritability of epigenetic alterations and intergenerational accountability, and concept of time implied by attempts to capture complex, non-linear gene-environment interactions. Finally, we reflect on the social epigenome as a conceptual space and try to identify barriers to translation, and practical and ethical issues raised by epigenetics research. In order for social epigenetics and social science to contribute to the emergence of this putative ‘science of social science’ and to capture meaningful human experience they will both need to change significantly.  相似文献   
182.
As most of Europe’s metropolitan landscapes grow, a change is occurring in their surrounding rural environment. The consequences thereof mainly involve losses of traditional land uses and changes in the socioecomic structures of the local population. The lack of coupling ‘urban society-countryside’ can be considered to constitute a driving force of this process. The present paper focuses upon the rural-urban network around the metropolis of Madrid (Central Spain). We developed a quantitative model to explain the socio-ecological rural-urban linkages, taking into account the influence of the metropolis in the network of neighbouring municipalities. The results show a rural landscape gradient ranging from silvo-pastoral to agricultural land uses and maintaining different interactions with the local socioeconomy. Urban-rural polarisation of the territory and accessibility to the metropolis are the main factors influencing the landscape dynamics. Territorial cohesion among municipalities and connectivity with the metropolis are factors determining the socio-ecological structure. The agricultural area presents good social cohesion, but a weak connection with the City. The silvo-pastoral landscape, on the contrary, maintains prominent links with the metropolis, but a non-significant interconnection between the small towns. The model tested constitutes a useful tool for analysing socio-ecological connectivity and for quantifying, designing and promoting territorial cohesion policies.  相似文献   
183.
Drawing on data from a novel survey of Californians, this article examines the relationship between anti-immigrant resentment and antiblackness. Over the last decade, there has been a significant increase in research on anti-immigrant resentment, as well as a steady growth in public opinion literature on antiblack bias. Nonetheless, there are almost no studies that examine the relationship between these types of attitudes. Using two different measures of anti-immigrant resentment and three different measures of antiblack bias, we find that antiblackness among those Californians surveyed was significantly and robustly correlated with anti-immigrant resentment. Our findings suggest that even in a state where there is a relatively small black population and where there is little overlap between the categories of “black” and “immigrant,” attitudes toward blacks may be shaping attitudes toward immigrants. The findings suggest a need to move beyond dyadic theories of othering and in doing so, to think more critically about how the racialization of one group can shape the racialization of other groups.  相似文献   
184.
ABSTRACT

The paper reports on a mixed methods study that sought to analyse determinants of youth labour market and educational disengagement in Peru. It begins by questioning the widespread focus on NEET – youth not in employment, education or training – as a measure of youth vulnerability in countries with extensive informal labour markets where labour precarity can be as problematic as unemployment for young people’s futures. A broader category of ‘urban vulnerable’ youth, including both NEET and precarious workers, is proposed and used as the basis for analysing the factors that influence young people’s trajectories. Key factors and shocks in youth trajectories are identified through qualitative life histories, and are tested using cross-section and panel survey data. Findings from the study have implications for the analysis of youth labour market vulnerability in the Global South, as well as for the policies that seek to address this problem.  相似文献   
185.

Background

Delayed childbearing is considered a risk factor for maternal–foetal health. As in other higher-income countries, in Spain age at maternity has steadily increased during the last two decades.

Aim

To quantify the impact of the delay in the age at maternity on small for gestational age (SGA) categories of <3rd, 3rd–5th and 5th–10th percentiles.

Methods

2,672,350 singleton live births born to Spanish mothers in 2007–2015 were analysed. Adjusted relative risk was calculated to estimate the adjusted partial population attributable fractions (PAFp) for mothers aged 35–39 and ≥40 years for each category of SGA considering the interaction between age at maternity and parity.

Findings

Primipara 35–39 years old mothers have the highest PAFp in the three categories of SGA, with the maximum value for SGA <3rd percentile (2.57%, 95% CI 2.25, 2.88). PAFp for both primipara and multipara ≥40 years old mothers were less than 1%. PAFp for primipara older mothers increased significantly in 2007–2015 for the three categories of SGA, more clearly among those aged 35–39 years. The contribution of multipara mothers of both age groups did not increase significantly during the period.

Conclusion

Delayed maternity is a significant adjusted risk factor for SGA, contributing to the increase of its prevalence. However, results also suggest a limited clinical impact of delayed maternity on foetal growth. Positive changes in maternal profile associated with the shift in maternal age might contribute to explain the limited impact of mothers aged 35 years and older on negative birth outcome in Spain.  相似文献   
186.
This study examines the postmen activity and the bag used in their task, which should transport the weight without affecting the locomotor system and the attitude of the worker. Studies were conducted on the activity of the postmen and transportation of loads, analyzing functional and ergonomic aspects of load distribution, as well as surveys with users, which made it possible to verify and prove the problems presented. Thus, the following work was developed in order to demonstrate the importance of applying an ergonomic product design.  相似文献   
187.
The aim of this paper is to measure the effectiveness of the organizations Information and Communication Technology (ICT) from the point of view of the manager, using Item Response Theory (IRT). There is a need to verify the effectiveness of these organizations which are normally associated to complex, dynamic, and competitive environments. In academic literature, there is disagreement surrounding the concept of organizational effectiveness and its measurement. A construct was elaborated based on dimensions of effectiveness towards the construction of the items of the questionnaire which submitted to specialists for evaluation. It demonstrated itself to be viable in measuring organizational effectiveness of ICT companies under the point of view of a manager through using Two-Parameter Logistic Model (2PLM) of the IRT. This modeling permits us to evaluate the quality and property of each item placed within a single scale: items and respondents, which is not possible when using other similar tools.  相似文献   
188.
This study aims to create awareness, both within the scientific community and among providers of sports facilities, for individuals with impaired or reduced mobility, promoting the development of technical solutions that allow greater autonomy and social integration of people with disabilities. The purpose of this work is, on the one hand, to evaluate the accessibility of sports facilities for people with reduced mobility and, on the other hand, to investigate why this user group has such low rates of participation in sporting activities. Firstly, using the Portuguese norms and legislation transcribed from European Community directives, a check list was created comprising all the items that sports facilities should abide by in order to provide accessibility and safety to people with reduced mobility. Another questionnaire was designed aimed at this user group, with questions pertaining to their desire and ability to use sports facilities. This questionnaire was distributed in Portugal, in the greater metropolitan area of Porto, to users of Rehabilitation Centres and Physiotherapy Clinics. The results obtained from the check-list showed the compliances and non-compliances of the respective sports facilities, proving that many barriers preventing the participation of people with reduced mobility still exist. Twenty-four people with permanent impairment of the lower extremities (paraplegia) answered the questionnaire pertaining to the desire and ability to perform physical activity. Two individuals (8%) had sporting activities available to them in their area of residence and only five (21%) performed any physical activity. The main reason given for not taking part in any activity was the lack of adapted sports facilities. All the participants felt that taking part in sports is beneficial. The benefits stated were: general well-being and development of the psychomotor component (e.g. coordination, balance, body posture), of physical condition (e.g. strength, resistance, flexibility) and social integration and quality of life. Besides wellbeing, they also mentioned social interaction, a way of occupying their time and an escape from the routine as the main motives for which they would like to take up physical exercise.  相似文献   
189.
In recent decades, there has been a rise in the use o lean production model techniques. Through this approach, companies become more flexible, a fact that increases the interest in studies regarding the introduction of this model in businesses and its impacts on working conditions. Important observations concerning ergonomics, such as the theme of work activity regulation, have been highlighted in such studies. This article aims to discuss strategies and regulations adopted by the workers on assembly lines that are considered flexible. The article presents the results of a study in a company that adopts some lean production techniques. The study was analyzed using the activity analysis as one of the premises of the Ergonomic Work Analysis (EWA). Many aspects of the traditional assembly line remain present in the scenario that was studied, however a new language was employed and aspects in the nature of regulations demonstrate that the relation with lean production techniques influence the operators' operational modes.  相似文献   
190.
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