Comparison of the EU T25 Single Point Estimate Method with Benchmark Dose Response Modeling for Estimating Potency of Carcinogens

The T25 single-point estimate method of evaluating the carcinogenic potency of a chemical, which is currently used by the European Union (EU) and is denoted the EU approach, is based on the selection of a single dose in a chronic bioassay with an incidence rate that is significantly higher than the background rate. The T25 is determined from that single point by a linear extrapolation or interpolation to the chronic dose (in mg/kg/day), at which a 25% increase in the incidence of the specified tumor type is expected, corrected for the background rate. Another method used to obtain a carcinogenic potency value based on a 25% increase in incidence above the background rate is the estimation of a T25 derived from a benchmark dose (BMD) response model fit to the chronic bioassay data for the specified tumor type. A comparison was made between these two methods using 276 chronic bioassays conducted by the National Toxicology Program. In each of the 2-year bioassays, a tumor type was selected based on statistical and biological significance, and both EU T25 and BMD T25 estimates were determined for that end point. In addition, simulations were done using underlying cumulative probability distributions to examine the effect of dose spacing, the number of animals per dose group, the possibility of a dose threshold, and variation in the background incidence rates on the EU T25 and BMD estimates. The simulations showed that in the majority of cases the EU T25 method underestimated the true T25 dose and overestimated the carcinogenic potency. The BMD estimate is generally less biased and has less variation about the true T25 value than the EU estimate.     

Teaching Students to Perform Assessments

In recent years, assessment methods and skills have been increasingly emphasized in the social work literature. Little information, however, has been provided about how to teach students assessment skills in a classroom setting. This article addresses that gap in the literature and presents an integrative skills assessment approach for teaching students to perform assessments. This approach is based on technical eclecticism and combines assessment methods and skills from three practice models: (1) psychosocial, (2) cognitive—behavioral, and (3) systems. Knowledge and skills about measurement, computerized assessment models and expert systems also are included in this approach to teaching assessment skills. The authors provide suggestions and tools for teaching assessment skills in a classroom, including an integrative skills assessment protocol and several techniques that may be used to teach students to gather assessment data. In teaching assessment skills, possible links may be developed with the field practicum and the classroom experience of students. In addition, the authors suggest that students benefit from the integrative skills approach. The approach is comprehensive, flexible, competency based, technological, and empirically based. However, shortcomings are that the approach is a clinical practice approach that excludes other forms of practice and that the integrative skills assessment approach does not help students develop skills for performing the rapid assessments frequently required for brief interventions.     

Teaching Family Policy Through a Policy Practice Framework

This article reports on the development of an innovative family policy practice course for direct practice students that emphasizes experiential learning to develop policy practice skills. The course uses a policy practice framework to understand the creation and implementation of major family legislation. A semester-long project provides students with opportunities to develop skills in advocacy, policy development, and planning by working for social change in the community. The article discusses examples of projects that have been implemented by students, discusses challenges to teaching experiential methods for skill building, and provides critical evaluation of the projects and their relevance for macro practice research.     

Field Note—From MSW to J-O-B: Using Field Seminar to Prepare Students for Employment

ABSTRACT

Social work field education is expected to help students transition from the classroom to the practice setting. Yet, few social work programs adequately provide career development support to increase students’ employability. This Field Note presents practical, relevant and immediate strategies for implementing the MSW to J-O-B curriculum innovation in the field practicum seminar. The purpose is to help students clarify professional goals and successfully obtain employment or career advancement opportunities following graduation. Formative evaluation results for this professional development curriculum are presented.     

Service Patterns of Adult Survivors of Childhood Versus Adult Sexual Assault/Abuse

This analysis compared the characteristics and service patterns of adult survivors of childhood sexual assault/abuse and adult survivors of adult sexual assault/abuse. Utilizing data from sexual assault crisis centers serving survivors in a Midwestern state over a six year period and controlling for revictimization, we describe and compare the demographic characteristics, referral sources, and service patterns of the two groups. Results indicate that paths into service differ for the two groups. Furthermore, adult survivors of childhood sexual assault/abuse obtain significantly more hours of service and service contacts on average than adult survivors of adult sexual assault/abuse. Implications for policy and practice are discussed.     

Editors' Introduction

For the professional middle class in information industries, “working from home” is an increasingly common feature of the employment landscape, resulting from the affordability and portability of information and communication technologies (ICTs). The phrase invokes a sense of freedom from the banality of the traditional office, offering flexibility in both working hours and location when other commitments prevail. In recent debates in Australian politics, working from home is also offered as an empowered choice for women who seek to combine paid work and childcare duties, thereby consecrating a preferable version of (post)feminist subjectivity suited to neoliberal economics and ideologies. This paper shows how these subjectivities have been represented in recent ICT advertising for two purposes: firstly, to highlight the role of mainstream media in normalising preferred uses of new media technology for work purposes; and secondly, to note how this process contributes to wider discourses limiting the aspirations of middle-class feminist politics to an individual level. In doing so, the paper seeks to question the ethical horizon of new media advertising as well as the feminist and labour politics upon which its appeal relies.     

The influence of dual‐identity development on the psychosocial functioning of African‐American gay and bisexual men

To examine the influence of racial‐ethnic and sexual identity development on the psychosocial functioning of African‐American gay and bisexual men (AAGBM), 174 AAGBM completed questionnaire packets designed to assess their levels of racial‐ethnic and sexual identity development, self‐esteem, social support, male gender role stress, HIV prevention self‐efficacy, psychological distress, and life satisfaction. The results indicate that AAGBM who possess more positive (i.e., integrated) seif‐identification as being African American and gay reported higher levels of self‐esteem, HIV prevention self‐efficacy, stronger social support networks, greater levels of life satisfaction, and lower levels of male gender role and psychological distress than their counterparts who reported less positive (i.e., less well integrated) African‐American and gay identity development. Although higher levels of racial‐ethnic identity development were associated with greater levels of life satisfaction, sexual identity development was not.     

The relationship between negative mood and sexuality in heterosexual college women and men

Negative mood states, such as depression and anxiety, are typically associated with decreased sexual interest and arousal. However, there is also some evidence that depressed or anxious mood may increase sexual interest or arousal in some individuals. In this study, 663 female college students (mean age = 18.9 years, SD = 1.21) answered questions regarding the effects of anxious and depressed mood on sexual interest and arousal and completed trait measures of sexual excitation and inhibition, anxiety, and depression. The majority of women reported decreased sexual interest and response when feeling depressed or anxious; a minority (about 10%) of women, however, reported increased sexual interest/response during anxious and depressed mood. This sample of women was compared to a sample of 399 college‐aged men. In general, men were more likely than women to report increased sexual interest during negative mood states. Of the variables explored, propensity for sexual excitation was the strongest predictor of the relationship between negative mood and sexuality in women. Individual differences in the effects of negative mood may prove relevant to our understanding of a variety of topics, including “risky” and “compulsive” sexual behavior and sexual dysfunction.     

Learning about a child's gay or lesbian sexual orientation: parental concerns about societal rejection, loss of loved ones, and child well being

This article reports the results of a study examining heterosexual parents' concerns upon learning about their children's gay or lesbian sexual orientations. Three areas of parental concern are noted: (a) those about what society thinks of them because they have gay or lesbian children, (b) those about being rejected by loved ones, and (c) concerns for their child's physical and psychological well being. Results indicate that parents' concerns about having gay or lesbian children differ depending on the gender of the parent, gender of the child, awareness of stigma, and perceptions of parents' own gender role attributes.