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131.
Jose M. Carbo Anupriya Daniel Casas Patricia C. Melo 《Journal of applied statistics》2019,46(9):1714-1723
This paper evaluates economic impacts arising from the introduction of high-speed rail (HSR) between Madrid and Barcelona. Using difference-in-differences estimation we estimate an average treatment effect for provinces with stops on the HSR line of 2.4% for economic output, 3.3% for numbers of firms, and 1.1% for labour productivity. We complement our DID results with a synthetic control analysis for Lleida and Tarragona, two provinces that we argue were assigned HSR stations largely due to their incidental location. We find that both the number of firms and labour productivity are substantially higher in these provinces than in their synthetic counterparts. 相似文献
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We derive a novel non-reversible, continuous-time Markov chain Monte Carlo sampler, called Coordinate Sampler, based on a piecewise deterministic Markov process, which is a variant of the Zigzag sampler of Bierkens et al. (Ann Stat 47(3):1288–1320, 2019). In addition to providing a theoretical validation for this new simulation algorithm, we show that the Markov chain it induces exhibits geometrical ergodicity convergence, for distributions whose tails decay at least as fast as an exponential distribution and at most as fast as a Gaussian distribution. Several numerical examples highlight that our coordinate sampler is more efficient than the Zigzag sampler, in terms of effective sample size. 相似文献
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Using a rich longitudinal data set of married couples from the Korean Labor and Income Panel Study, this article seeks to uncover the intramarital allocation of experienced utility and its drivers. We find both substantial gains from marriage and effects of relative predicted earnings outside of marriage on relative gains from marriage. These findings are consistent with cooperative bargaining models and with models viewing individuals as having a demand for household production services by a spouse, with market forces influencing the price of such services. In addition, we find that men benefit more from marriage than women and that this gender gap is more pronounced for older couples. This is likely to be due to social norms and prescribed gender roles which are more prevalent within the older generation. 相似文献
135.
Robust Bayesian nonlinear mixed‐effects modeling of time to positivity in tuberculosis trials 下载免费PDF全文
Early phase 2 tuberculosis (TB) trials are conducted to characterize the early bactericidal activity (EBA) of anti‐TB drugs. The EBA of anti‐TB drugs has conventionally been calculated as the rate of decline in colony forming unit (CFU) count during the first 14 days of treatment. The measurement of CFU count, however, is expensive and prone to contamination. Alternatively to CFU count, time to positivity (TTP), which is a potential biomarker for long‐term efficacy of anti‐TB drugs, can be used to characterize EBA. The current Bayesian nonlinear mixed‐effects (NLME) regression model for TTP data, however, lacks robustness to gross outliers that often are present in the data. The conventional way of handling such outliers involves their identification by visual inspection and subsequent exclusion from the analysis. However, this process can be questioned because of its subjective nature. For this reason, we fitted robust versions of the Bayesian nonlinear mixed‐effects regression model to a wide range of TTP datasets. The performance of the explored models was assessed through model comparison statistics and a simulation study. We conclude that fitting a robust model to TTP data obviates the need for explicit identification and subsequent “deletion” of outliers but ensures that gross outliers exert no undue influence on model fits. We recommend that the current practice of fitting conventional normal theory models be abandoned in favor of fitting robust models to TTP data. 相似文献
136.
Robert C. Abrams Pamela Ansell Risa Breckman Jason Karlawish Mark Lachs Deborah Holt-Knight 《Journal of elder abuse & neglect》2019,31(3):244-254
We present the Interview for Decisional Abilities (IDA), a semi-structured tool for use by adult protective services (APS) workers as part of their comprehensive assessments of clients. The IDA was created in response to a Federal mandate to standardize the procedures and competencies of APS agencies with a view to improving client assessments and facilitating cross-jurisdictional research on adult mistreatment. The proximal aim of the IDA is to guide workers in gathering information on the ability of suspected victims of adult mistreatment to make decisions about the risks they face. 相似文献
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The tragic killing of George Floyd at the hands of the police resulted in hundreds of thousands of protestors marching in the streets demanding change. The call for change criticized the killing of Blacks by law enforcement and challenged White supremacy as an institution of social control and racial violence. A key component of the marches and protests was a message to the residents of the United States: “Black Lives Matter.” As society grapples with a reckoning, researchers studying police violence for the past 6 decades have been empirically and theoretically debating the reasons why use of force by law enforcement continues to have a higher proportion of Black and Brown victims compared to Whites. Although the research on fatal police killings was studied by only a small number of individuals prior to 2014, after the killing of Michael Brown in Ferguson, Missouri the research in different areas of the country increased rapidly as did the forms of analysis and research disciplines making their own contributions. The Washington Post and Guardian news agencies established that deaths at the hands of the police were occurring for at least 900 to 1100 individual deaths per year for which firearms resulted in the greatest cause of death. As US government agencies failed to produce a national data source on police involved killings, the media took a leading role in providing greater national understanding. The authors examine what role academic researchers contribute to the discussion for solutions, particularly those from marginalized backgrounds. As protestors march, lawyers sue and defend, and politicians create new forms of legislation, researchers need to play a more important role initiating critical studies, making sense of the data, and providing a theoretical framework for which police violence can be understood. This article will provide an overview of the literature on racialized police violence, point out key patterns involving racial and ethnic disparities, and emphasize how researchers can play a more important role in advocating for change. 相似文献
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PCORnet, the National Patient-Centered Clinical Research Network, seeks to establish a robust national health data network for patient-centered comparative effectiveness research. This article reports the results of a PCORnet survey designed to identify the ethics and regulatory challenges anticipated in network implementation. A 12-item online survey was developed by leadership of the PCORnet Ethics and Regulatory Task Force; responses were collected from the 29 PCORnet networks. The most pressing ethics issues identified related to informed consent, patient engagement, privacy and confidentiality, and data sharing. High priority regulatory issues included IRB coordination, privacy and confidentiality, informed consent, and data sharing. Over 150 IRBs and five different approaches to managing multisite IRB review were identified within PCORnet. Further empirical and scholarly work, as well as practical and policy guidance, is essential if important initiatives that rely on comparative effectiveness research are to move forward. 相似文献