A modified random-effect procedure for combining risk difference in sets of 2×2 tables from clinical trials

Summary Meta-analyses of sets of clinical trials often combine risk differences from several 2×2 tables according to a random-effects model. The DerSimonian-Laird random-effects procedure, widely used for estimating the populaton mean risk difference, weights the risk difference from each primary study inversely proportional to an estimate of its variance (the sum of the between-study variance and the conditional within-study variance). Because those weights are not independent of the risk differences, however, the procedure sometimes exhibits bias and unnatural behavior. The present paper proposes a modified weighting scheme that uses the unconditional within-study variance to avoid this source of bias. The modified procedure has variance closer to that available from weighting by ideal weights when such weights are known. We studied the modified procedure in extensive simulation experiments using situations whose parameters resemble those of actual studies in medical research. For comparison we also included two unbiased procedures, the unweighted mean and a sample-size-weighted mean; their relative variability depends on the extent of heterogeneity among the primary studies. An example illustrates the application of the procedures to actual data and the differences among the results. This research was supported by Grant HS 05936 from the Agency for Health Care Policy and Research to Harvard University.     

Working with Deaf People

Whilst 17% of the population experience some degree of hearing loss, sociology has largely neglected the study of services to this group. This article attempts to move the debate from a sociology of the deaf community to a sociology of deafness that includes an examination of how professionals define the needs of hearing impaired people. Despite differences between different constructions, deafness workers offer a combination of social work, information, and interpreting services. Practice rules have been developed by deafness workers to control workloads, and to work in their preferred way. This article is based on a multi-layered approach with a contextual analysis, a survey of 123 deafness workers, 32 semi-structured interviews, and my own personal experience of deafness work.     

The Farm Crisis and Mental Health: A Longitudinal Study of the 1980s1

Abstract This paper examines rural/urban differences and trends in mental health during the farm crisis of the 1980s in a large panel sample from a midwestern state. A community research perspective, which attributes differences to life styles, culture, and community context, is contrasted with an economic stress perspective, which focuses on individual differences in economic circumstances as determinants of rural-urban differences in mental health. Survey samples from 1981, 1986, and 1989 are used to examine differences among seven categories of community type. Multiple regression analysis of the trend and panel data provide support for both the individual economic distress and community context models.     

Police Reforms in Child Abuse Investigation: Their Success and Limitations in the Struggle to Uphold Children's Rights

SUMMARY. The past decade has shown increased awareness, concern and understanding about the extent of child abuse, particularly sexual abuse, and the caring agencies response to listen to and to support the young victims. This article looks at the response of the police service over that decade to meet such demands and to work jointly and responsively with social services to further the welfare and protection of children. It also examines the constraints and limitations of the police and social services when they attempt to uphold the rights of child victims and to gain redress through the criminal justice system     

MINING ERROR VARIANCE AND HITTING PAY-DIRT:

According to traditional error theory, sentiment measurements vary unsystematically from individual to individual. However, we find some patterned deviation in sentiments that characterize subsets of respondents within a seemingly homogeneous population. After demonstrating the existence of such patterns, we report an exploratory study aimed at identifying social characteristics of people with different patterns of sentiments. People embedded in multiple social networks have exaggerated sentiments that contour cultural patterns, and people with few social associations have attenuated sentiments conveying cultural detachment. In addition, people with disciplinary parents and romantic privation have some distinctive sentiments, depending on their gender.