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141.
A growing population of older adults receive treatment for depression but remain symptomatic. We report on a feasibility pilot study of an intervention (ACTIVATE) to improve depression care by encouraging the older person to take a step to intensify the existing treatment. Older adults (N = 43) receiving home-meal service and in depression treatment, but still symptomatic, participated in the ACTIVATE intervention. Assessments were conducted to evaluate change in treatment. Many (66.6%) participants took a step to change their treatment; the rate (88.2%) was higher among individuals with major depression. ACTIVATE may be a useful social work intervention to improve depression care.  相似文献   
142.
Early individual differences in prosocial behaviors are pivotal for children's peer relationships. To investigate the interplay among verbal ability, emotion understanding, and mother–child mutuality as predictors of prosocial behaviors, we observed 102 children at the ages of two, three, and four. All time points included verbal ability and emotion understanding tests and both video‐based and maternal ratings of prosocial behavior. The first two time points also included video‐based ratings of mother–child mutuality. The third time point included teacher ratings of prosocial behavior and an experimental task. Regression analysis demonstrated robust associations between emotion understanding at the age of three and prosocial behavior at the age of four. Path analysis showed that emotion understanding at the age of three mediated associations between verbal ability/mother–child mutuality at the age of two and prosocial behavior at the age of four.  相似文献   
143.
The development of a new drug is a major undertaking and it is important to consider carefully the key decisions in the development process. Decisions are made in the presence of uncertainty and outcomes such as the probability of successful drug registration depend on the clinical development programmme. The Rheumatoid Arthritis Drug Development Model was developed to support key decisions for drugs in development for the treatment of rheumatoid arthritis. It is configured to simulate Phase 2b and 3 trials based on the efficacy of new drugs at the end of Phase 2a, evidence about the efficacy of existing treatments, and expert opinion regarding key safety criteria. The model evaluates the performance of different development programmes with respect to the duration of disease of the target population, Phase 2b and 3 sample sizes, the dose(s) of the experimental treatment, the choice of comparator, the duration of the Phase 2b clinical trial, the primary efficacy outcome and decision criteria for successfully passing Phases 2b and 3. It uses Bayesian clinical trial simulation to calculate the probability of successful drug registration based on the uncertainty about parameters of interest, thereby providing a more realistic assessment of the likely outcomes of individual trials and sequences of trials for the purpose of decision making. In this case study, the results show that, depending on the trial design, the new treatment has assurances of successful drug registration in the range 0.044–0.142 for an ACR20 outcome and 0.057–0.213 for an ACR50 outcome. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
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145.
To test for the presence of role model effects of female high school faculty and professional staff on young women in high school, we estimate several models of educational attainment for young women using data from the National Longitudinal Survey of Youth. Exposure to female high school faculty and professional staff has a positive impact on the educational attainment of young women. This result, combined with our finding that female faculty and professional staff have no significant impact on the educational attainment of young men, supports a female role model hypothesis.  相似文献   
146.
Racism, in various forms, remains a dominant feature in Australian society. Aboriginal Australians are commonly targets of racial discrimination. However, understanding racism is difficult given that racial attitudes vary towards particular groups of people, across place and time and are difficult to measure. This paper presents responses of residents across four rural shires in Victoria to questions about attitudes towards Aboriginal people/issues. Responses indicated that attitudes towards Aboriginal people were diverse and that individuals varied in their attitudes on specific items. There were subtle differences between the four sites and association between demographic characteristics and some items in particular sites. This suggests that respondents are inconsistent in their attitudes relating to Aboriginal people/issues and that there are place‐based influences on these attitudes. We conclude that the many varied understandings of racism and Aboriginal Australians allow the discourses of exclusion, disempowerment and othering to be maintained.  相似文献   
147.
This paper examines the socialization and adjustment experiences of newcomers to organizations from a role stress perspective. A longitudinal field study is reported which tested a three-stage socialization model using physiological and psychological distress symptoms, general satisfaction, and intention to leave the organization as indicators of newcomer adjustment. Data were collected from newcomers (the focal role) (N = 91) at three times during me study and also from their supervisors (the role senders) (N = 41). While the data confirmed the general utility of the model, it also suggested some revisions by way of new and altered pathways between some of the variables.  相似文献   
148.
Management accounting techniques and information are often accused of having many limitations that are likely to constrain investment in new technology. However, relatively little is known about the actual influence of management accounting practices on investment decisions. The empirical evidence of this research shows that new technology investment decisions are both highly complex and political. These decision attributes give rise to a protracted, circuitous, decision process that is very different from the rational model which dominates the capital budgeting literature. The research also shows that the management accounting system captures only a fraction of the information generated by this process and consequently has a relatively low influence on these investment decisions.  相似文献   
149.
The experiences of children who live with parental mental illness are becoming increasingly recognized. However, there remains a limited body of knowledge in relation to an individual's longer term experiences. This study sought adult children's experiences of childhood parental mental illness. It generated reflections of 13 adult children who had lived with parents with mental illness during their childhood. The narrative design of the study facilitated a voice for participants. The paper presents one main theme of the findings. The findings offer a unique insight into childhood awareness of social stigmas and children's behavioural changes to avoid disclosure of parental mental illness. Participants noted that they were aware of social stigmas associated with mental illness during their childhood. This contributed to their fear of disclosure to others that fuelled a culture of familial secrecy, reinforcing the children's own sense of difference. Further work is required to enhance community understanding about the familial journeys of parental mental illness and the impact of negative‐natured stigmas.  相似文献   
150.
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