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31.
Stephen T. Russell 《Journal of research on adolescence》2002,12(3):305-324
Adolescence is often assumed to be the most important period of life for understanding teen childbearing risk. Developmental perspectives challenge that assumption, offering the possibility that early childhood characteristics may have unique and lasting effects on the risk for teen childbearing. This study examined family life risk factors (socioeconomic status, family stress, and parental involvement in education) and how their effects on teen childbearing risk varied, depending on the childhood age at which they were experienced. Prospective life history data from the National Child Development Study of Great Britain were used to study a birth cohort of 4,928 British women, 15.3% of who became pregnant as teens. This study demonstrated that data from early childhood significantly contribute to the understanding of teen childbearing risk. 相似文献
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The training of medical practitioners to improve the practitioner/patient relationship may be difficult, as limitations often exist on the choice of patients included in the study. A specific study of this type of training is given. It is proposed that a simple modification and generalization of Yates' plaid-square designs be used. It is shown that a replicated plaid-design incorporates as a special case the criss-cross or strip-plot design. The usefulness of these designs in studies of the training of medical practitioners is illustrated. The basic characteristics of their analysis are outlined. 相似文献
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Nicholas T. Longford 《Statistics and Computing》2003,13(1):67-80
The weaknesses of established model selection procedures based on hypothesis testing and similar criteria are discussed and an alternative based on synthetic (composite) estimation is proposed. It is developed for the problem of prediction in ordinary regression and its properties are explored by simulations for the simple regression. Extensions to a general setting are described and an example with multiple regression is analysed. Arguments are presented against using a selected model for any inferences. 相似文献
37.
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical
data are intrinsically stochastic and tend to be observed by means of discrete-time sampling systems, which are often limited
in their completeness. In this paper we explore how to make Bayesian inference for the kinetic rate constants of regulatory
networks, using the stochastic kinetic Lotka-Volterra system as a model. This simple model describes behaviour typical of
many biochemical networks which exhibit auto-regulatory behaviour. Various MCMC algorithms are described and their performance
evaluated in several data-poor scenarios. An algorithm based on an approximating process is shown to be particularly efficient. 相似文献
38.
Yen Steven T. Douglass Shaw W. Eiswerth Mark E. 《Review of Economics of the Household》2004,2(1):73-88
Asthma patients' health status may be especially sensitive to some types of air pollution, but the evidence on this is mixed. We explore the effects of ground-level ozone on asthma patient's activities, breaking apart the usual aggregated category of leisure into indoor and outdoor activities, and differentiating those by whether the activities were active or inactive. Applying the semiparametric censored estimation method we demonstrate that even though the period over which activities were observed was relatively low in ozone levels, there is a significant impact of ozone on a few activities. The (non-ozone) economic and demographic variables in the model play significant roles in explaining the allocation of time among seven activities, suggesting the suitability of the approach for other household decision-making contexts. 相似文献
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Regina Thompson Paul H. Templet John K. Gamman Scott T. McCleary Margaret A. Reams 《Risk analysis》1994,14(5):857-861
The goal of Louisiana's 1990–1991 comparative risk project, also called the Louisiana Environmental Action Plan (LEAP), was to incorporate risk assessment into state environmental planning and policymaking. Scientists, government officials, and citizens were brought together to estimate the relative risk to human health, natural resources, and quality of life posed by 33 selected environmental issues. The issues were then ranked according to their relative estimated risks. It was hoped that this ranking of "comparative risks" would enable state policymakers to target the most important environmental problems and allocate scarce public resources more rationally and efficiently. As a result of the project, the governor issued an Executive Order forming a permanent Public Advisory Committee to continue this type of comparative risk assessment in Louisiana. 相似文献