Are Research Papers Reporting Results from Nutrigenetics Clinical Research a Potential Source of Biohype?

Nutrigenetics is a promising field, but the achievability of expected benefits is challenged by the methodological limitations that are associated with clinical research in that field. The mere existence of these limitations suggests that promises about potential outcomes may be premature. Thus, benefits claimed in scientific journal articles in which these limitations are not acknowledged might stimulate biohype. This article aims to examine whether nutrigenetics clinical research articles are a potential source of biohype. Of the 173 articles identified, 16 contained claims in which clinical applications were extrapolated from study results. The methodological limitations being incompletely acknowledged, these articles could potentially be a source of biohype.     

Hanging together, or hanging separately

While lack of structure often satisfies physicians' desire for independence, it also leads to a wide range of problems. Examine a proven approach to creating an effective group governance structure.     

Associations of eldercare and competing demands with health and work outcomes among manufacturing workers

Employees juggling eldercare and work report work–family conflicts and poor health-related outcomes, but little is known about eldercare demands (ECDs) in the context of competing demands in the manufacturing workforce. This study determines how ECDs vary by age, gender, income, and job category, and how ECDs and competing demands are associated with health-related and work-related outcomes, among manufacturing workers. Employees from six manufacturing companies completed questionnaires. ECDs were defined as providing assistance to an adult aged 65 and older due to disability or chronic illness; those with ECDs were asked how many care-hours per week and whether assistance included personal care. Workers over age 45 were more likely than younger workers to report ECDs. After adjusting for competing demands and socio-demographic characteristics, ECDs were associated with greater depressive symptoms and family-to-work conflict (FWC), providing 5 or more hours of eldercare weekly was associated with greater depressive symptoms, and providing personal care was associated with greater FWC.     

Erosion handelsrechtlicher GoB durch das Bilanzrechtsmodernisierungsgesetz

The Accounting Law Modernization Act (BilMoG) aims at harmonizing two basic attitudes that are irreconcilable in the first place: On the one hand the local German GAAP, which are driven by creditor protection, the principle of prudence as well as objective limitations; on the other hand international accounting standards (IFRS), which focus on information tasks. The option to capitalise certain intangible fixed assets that have not been acquired from a third party, leads to a de-objectification of the balance sheet that has to be rejected as being too hazardous. Furthermore, the introduction of fair-value accounting for financial instruments acquired for trading purposes has to be rejected due to a breach of the realisation principle. The primary legal purpose of the balance sheet, the prudent determination of distributable profits on the basis of turnover, would be jeopardized. The desire for information on investment in intangible assets as well as the (alleged) increase in value of financial instruments should rather be displayed in the notes to the financial statements.     

Promoting Responsible Conduct of Research: A Canadian Perspective

This article compares the current Canadian and American approaches to governing the responsible conduct of research. The Canadian Secretariat on Responsible Conduct of Research acts on behalf of Canada's three federal research agencies to implement their Framework on Responsible Conduct of Research. It operates not on the basis of regulatory authority, like its U.S. counterpart, the Office of Research Integrity, but rather on the basis of making compliance a condition of eligibility for funding. Both offices are dedicated to promoting good research practices and to enforcing good standards of research practice.     

Understanding the roles of subjective and objective aspects of time in the work-family interface

The experience of time has been posited as an important predictor of work-family conflict; however, few studies have considered subjective and objective aspects of time conjointly. This study examined the reported number of hours dedicated to work and family as indices of objective aspects of time, and perceived time pressure (in the work and family domains respectively) as an important feature of the subjective nature of temporal experiences within the work-family interface. Results indicate that the stress of having insufficient time to fulfill commitments in one domain (i.e., perceived time pressure) predicts work-family conflict, and that perceived time pressures predict the amount of time allocated to a domain. Additionally, findings suggest that domain boundaries are not symmetrical, with work boundaries being more rigidly constructed than family boundaries. Work-to-family and family-to-work conflict were generally related to overall health, turnover intentions, and work performance, as expected.     

试论我国未来图书馆发展的兼容性

文章从历史的发展的观点出发通过对我国图书馆事业发展的回顾,提出在21世纪图书馆将如何发展,并对传统图书馆和数字图书馆的优势互补问题做出分析,指出未来图书馆发展模式是传统图书馆与数字图书馆的复合,二者将相互依存,兼容发展。     

Researchers’ Views of the Acceptability of Restrictive Provisions in Clinical Trial Agreements with Industry Sponsors

We conducted a mail survey of 884 U.S. medical school faculty active in clinical research to elicit their views about the acceptability of provisions in contracts for industry-sponsored clinical trials that would restrict investigators’ academic freedom and control over trials. We compared their responses to results from a similar survey of research administrators at 107 medical schools. There was substantial variation among clinical researchers in their acceptability judgments, with a relatively large proportion of clinical trial investigators willing to accept provisions that give industry sponsors considerable control over the dissemination of research results. There were significant differences in the perceptions of clinical trial investigators versus other recently published clinical researchers; investigators with a high versus low percentage of research support from industry; junior versus senior faculty; and investigators at institutions with high versus low National Institute of Health (NIH) funding ranks. There was also a significant divergence of views in a number of areas between clinical trialists and research administrators who negotiate clinical trial contracts on their behalf. Medical school faculty could benefit from additional guidance about what their institution views as acceptable parameters for industry-sponsored clinical trial agreements.     

Benefits Associated with Nutrigenomics Research and Their Reporting in the Scientific Literature: Researchers' Perspectives

Nutrigenomics and nutrigenetics (NGx) are fields of research that have raised significant expectations about their potential benefits. This article presents empirical data from an online survey seeking the opinions of NGx researchers (n = 126) regarding the achievability of the potential benefits of NGx, the time envisioned for their realization, the motives that may lead to their explicit mention in scientific peer-reviewed articles and the audience(s) targeted by NGx researchers when reporting their results in such articles. Results show that caution should be taken to avoid the risks associated with biohype and the premature dissemination of the potential benefits of NGx among various audiences.     

Voice and Agency in Social Movement Outcomes

Focusing on the interactional dynamics of movements, we find that two constructs, voice and agency are critical to the development of a sense of “groupness” and can aid social movement actors in accomplishing desired goals. Voice and agency are accomplished when movement actors engage in various processes such as planning and strategizing, completion of goal-oriented tasks and other unifying activities. We examine four social movement organizations operating in separate movement contexts with different outcomes: contested gay politics in Cincinnati, Ohio and grassroots feminism in Cleveland, Ohio and New York City, New York. We find that groups will have a better chance at achieving their goals if members are able to create a unified voice, and if leaders include and draw from the strengths of those they recruit, thus allowing a sense of agency.