The contraceptive transition in Flanders

Changes in contraceptive use in Flanders are documented, largely though not solely using data from four surveys conducted between 1966 and 1983. Particular attention is paid to changes in the methods of contraception used. The contraceptive transition observed for Flanders is compared with information for other countries to assess whether a specific pattern can be delineated.     

Innate immunity, local inflammation, and degenerative disease

The brain lesions associated with Alzheimer's disease (AD), which are referred to as neurofibrillary tangles and senile plaques, are characterized by the presence of a broad spectrum of inflammatory mediators. Surprisingly, these mediators, which include complement proteins, inflammatory cytokines, prostaglandins, and acute phase reactants such as C-reactive protein and amyloid P, are produced by resident brain cells, including neurons. Although secondary to the fundamental pathology caused by the presence of tangles and plaques, there is strong evidence that inflammation exacerbates the neuronal loss. In particular, AD lesions show evidence of self-attack by the complement system--a part of the immune system that normally functions to rid the body of invading pathogens. However, the lesions are devoid of significant T cell infiltration, a hallmark of an inflammatory immune response, and antibodies. We define this phenomenon as autotoxicity to distinguish it from classical autoimmunity, in which the body raises antibodies to normal endogenous macromolecules. Locally produced inflammatory mediators have also been identified in atherosclerotic plaques, along with evidence of complement self-attack. As was previously shown for heart attacks, epidemiological evidence indicates that extended use of nonsteroidal anti-inflammatory drugs (NSAIDs) results in a reduced risk of AD. NSAIDs inhibit the production of prostaglandin inflammatory mediators, but powerful new therapeutic agents might be developed by targeting more critical inflammatory mechanisms, especially the complement system.     

The Influence of Advance Letters on Response in Telephone Surveys: A Meta-Analysis

Recently, the leading position of telephone surveys as the majormode of data collection has been challenged. Telephone surveyssuffer from a growing nonresponse, partly due to the generalnonresponse trend for all surveys and partly due to changesin society and technology influencing contactability and willingnessto answer. One way to counteract the increasing nonresponseis the use of an advance letter. In mail and face-to-face surveys,advance letters have been proven effective. Based on the proveneffectiveness in face-to-face and mail surveys, survey handbooksadvise the use of advance letters in telephone surveys. Thisstudy reviews the evidence for this advice and presents a quantitativesummary of empirical studies on the effectiveness of advanceletters in raising the response rate for telephone surveys.The major conclusion is that advance letters are also an effectivetool in telephone surveys, with an average increase in responserate (RR1) from 58 percent (no letter) to 66 percent (advanceletter), and an average increase in cooperation rate (COOP1)from 64 percent (no letter) to 75 percent (advance letter).     

A qualitative study of how caseload midwifery is experienced by couples in Denmark

Background

Caseload midwifery is expanding in Denmark. There is a need for elaborating in-depth, how caseload midwifery influences the partner and the woman during childbirth and how this model of care influences the early phases of labour.

Dismantling Public Housing,Reconstructing the Lives of Children

Just as the lives of adults may be turned upside down when a move is made from public housing, so too may be the lives of children. Over the course of 5 years, mothers relocated out of a housing development in the southwest U.S. participated in surveys and focus groups, discussing among many topics the lives of their children after the move. Mothers talked about their children's behaviour, the lack of play spaces, their children experiences in their schools, and the schools' responses. The mothers offered insights into ways to ease the relocation process and make the new space home.     

Internationalization from Central and Eastern Europe: A systematic literature review

Economic transition in Central and Eastern Europe (CEE) has led to a dramatic increase in CEE firms' participation in international markets. This applies to different types of firms – from large emerging market multinationals to small international new ventures. In this paper, we systematically review the research on CEE outward internationalization, which we define as internationalization of CEE-based firms in the form of exporting or FDI, and contribute to literature by providing a complete picture of the state of the art and outlining potential avenues for future research. We find that while the CEE region has been described as a fruitful ground for developing new and testing existing theories, it heavily loads on the latter. We suggest that greater reliance on theories and concepts from the field of entrepreneurship and a stronger focus on internationalization decision processes might further enrich our understanding of internationalization from CEE.