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81.
Jennifer A. Richter Abraham S.D. Tidwell Erik Fisher Thaddeus R. Miller 《Innovation: The European Journal of Social Science Research》2017,30(3):365-384
Since the first electrification systems were established in the United States between 1910 and 1930, energy systems governance at the municipal level has included competing visions for how engineering design and energy policy-making should foster particular social outcomes. Using Phoenix as a representative metropolitan area, and the cases of distributed generation and in-home power management devices as examples, this paper explores how the norms and values embedded in energy systems design and planning shape how residents experience change in the energy grid. Through these case studies, the authors argue that such “sociotechnical imaginaries” – collectively formed visions of social life related to science and technology development – are a crucial, yet overlooked, pathway for social science to engage in fostering socially reflexive mechanisms in energy development. To conclude, the authors outline a research program for applying the established methodology of socio-technical integration research (STIR) in order to develop socially reflexive capacities in municipal energy producing, regulating, and planning institutions. Such a program has the ability to produce a deeper intellectual understanding of how energy development occurs, and in doing so generate new pathways for fostering cultural and material changes in the structure of contemporary energy systems. 相似文献
82.
T-cell engagers are a class of oncology drugs which engage T-cells to initiate immune response against malignant cells. T-cell engagers have features that are unlike prior classes of oncology drugs (e.g., chemotherapies or targeted therapies), because (1) starting dose level often must be conservative due to immune-related side effects such as cytokine release syndrome (CRS); (2) dose level can usually be safely titrated higher as a result of subject's immune system adaptation after first exposure to lower dose; and (3) due to preventive management of CRS, these safety events rarely worsen to become dose limiting toxicities (DLTs). It is generally believed that for T-cell engagers the dose intensity of the starting dose and the peak dose intensity both correlate with improved efficacy. Existing dose finding methodologies are not designed to efficiently identify both the initial starting dose and peak dose intensity in a single trial. In this study, we propose a new trial design, dose intra-subject escalation to an event (DIETE) design, that can (1) estimate the maximum tolerated initial dose level (MTD1); and (2) incorporate systematic intra-subject dose-escalation to estimate the maximum tolerated dose level subsequent to adaptation induced by the initial dose level (MTD2) with a survival analysis approach. We compare our framework to similar methodologies and evaluate their key operating characteristics. 相似文献
83.
Matthias Menter Erik E. Lehmann Torben Klarl 《Zeitschrift für Betriebswirtschaft》2018,88(9):1105-1132
As higher education policies are often associated with intense public spending, the evaluation and performance measurement of respective initiatives becomes increasingly crucial. An extensive and fruitful strand of literature has dealt with the assessment of university performance, yet mainly focused on point-in-time rather than period-of-time examinations. This study investigates the effects of Germany’s first Excellence Initiative, a political measure aimed at building up world-class universities to be able to compete in the globalizing research world. Relying on both qualitative and quantitative measures, taking into account a 15-year period from 1998 to 2012, we analyze the selection process and how and whether the Excellence Initiative fulfilled its ambitious goals. Our results suggest that not the political initiative per se, i.e. the treatment, but the announcement of the treatment triggered diverging performance paths within the German higher education system, thus positively contributed to augmented research performance of the promoted universities. Based on these findings, we provide policy recommendations and avenues for future research. 相似文献
84.
Digitalisation, flexible job markets, new technologies and innovative forms of collaboration constitute increasing challenges for employers and the design of modern work. But how can we deal with these challenges and what do we know about the effect of good versus bad work design? Based on the job demands-resources model (JRM), we present a simulation-based training during which participants experience the effects of different work characteristics. We focus on the moderating effects of job control and job demands: The JRM assumes that job demands and job control interactively affect employee exhaustion and work engagement: Jobs with high control can buffer the strain-enhancing effect of job demands (buffer hypothesis) and increase work engagement (active learning hypothesis). We test these hypotheses in a workplace simulation during which participants have to produce ice-cream. Our results support the buffer hypothesis but not the active learning hypothesis. We discuss the added value of work design simulations for organisations, practitioners, and HR professionals. 相似文献
85.
Ola Andersson Hkan J. Holm Jean‐Robert Tyran Erik Wengstrm 《Journal of the European Economic Association》2016,14(5):1129-1154
Recent experimental studies suggest that risk aversion is negatively related to cognitive ability. In this paper we report evidence that this relation may be spurious. We recruit a large subject pool drawn from the general Danish population for our experiment. By presenting subjects with choice tasks that vary the bias induced by random choices, we are able to generate both negative and positive correlations between risk aversion and cognitive ability. Our results suggest that cognitive ability is related to random decision making rather than to risk preferences. (JEL: C81, C91, D12, D81) 相似文献
86.
Against the backdrop of occasional claims by social scientists that class analysis is no longer relevant this article will study the consumption patterns of different classes. Two hypotheses are derived and tested. These are to assume that classes' consumption differences are due to processes of social closure, or are of a cultural kind. This is investigated using a Swedish family expenditure data-set from 1992. The focus is on classes' different uses of their incomes regarding basic expenditures, expenditures on non-durables and ownership of durables. The most striking result is that 'higher' classes tend to spend a great deal of money on activities outside the home, 'appearance' and information, while other classes' consumption resembles the 'higher' classes, to different degrees. Moreover, the class hierarchy, constructed theoretically from employment factors, resembles a hierarchy constructed from similarities in patterns of consumption. The main conclusion is that class matters, in interesting ways, for consumption, though there are also other powerful factors. The closure hypothesis receives support, even though a combination of the two hypotheses seems sound. 相似文献
87.
Loan repayment can be viewed as a sequence of instalments. Instalments can either fall over time (i.e., repaying more in the beginning and less in the end), rise or stay constant. Three studies investigated whether the well-established preference for improvement (i.e., falling profiles) can also be observed in a loan context. Results show that consumers do prefer falling profiles over rising profiles; however, also a strong preference for constant profiles was found. These preferences for improvement and spreading even outweigh financial benefits. Consumers, hence, may sometimes opt for the financially worse loan option. Financial capability programs could benefit from including information about the perception of sequences. 相似文献
88.
Annemiek T. Harder Erik J. KnorthMargrite E. Kalverboer 《Children and youth services review》2011,33(12):2482-2488
Many adolescents who make the transition to adulthood experience problems after their departure from secure residential care. Research suggests that these young people are often in need of support after they have left secure care. Little is known about the experiences and perceptions of adolescents during and after this transition. The aim of this article is to assess these experiences for a group of 24 adolescents in the Netherlands that have left secure residential care. The results show, in line with previous studies, that many adolescents experience problems during their transition from secure care, especially with regard to finances, school and employment, and living arrangements. In contrast to other studies, a majority of the adolescents reports to have received support in the year following their departure. Relatively few adolescents move to independence after their departure, which suggests that many adolescents are not ready for making a true transition into adulthood yet. 相似文献
89.
Tor Jacobson Erik von Schedvin 《Econometrica : journal of the Econometric Society》2015,83(4):1315-1371
Using an exhaustive data set on claims held by trade creditors (suppliers) on failed trade debtors (customers), we quantify the importance of trade credit chains for the propagation of corporate bankruptcy. We show that trade creditors experience significant trade credit losses due to trade debtor failures and that creditors' bankruptcy risks increase in the size of incurred losses. By exploring the roles of financial constraints and creditor‐debtor dependences, we infer that the trade credit failure propagation mechanism is driven by both credit losses and demand shrinkage. Finally, we show that the documented propagation mechanism constitutes a significant part of the overall bankruptcy frequency, suggesting that it has measurable implications for the aggregate level. 相似文献
90.