Nonparametric Trend Estimation for Periodic Autoregressive Time Series

A periodically stationary time series has seasonal variances. A local linear trend estimation is proposed to accommodate unequal variances. A comparison of this proposed estimator with the estimator commonly used for a stationary time series is provided. The optimal bandwidth selection for this new trend estimator is discussed.     

A Note on the Likelihood Ratio Test for Equality of k Normal Populations

The authors derive the analytic expressions for the mean and variance of the log-likelihood ratio for testing equality of k (k ≥ 2) normal populations, and suggest a chi-square approximation and a gamma approximation to the exact null distribution. Numerical comparisons show that the two approximations and the original beta approximation of Neyman and Pearson (1931 Neyman , J. , Pearson , E. S. ( 1931 ). On the problem of k samples . In: Neyman , J. , Pearson , E. S. , eds. Joint Statistical Papers . Cambridge : Cambridge University Press , pp. 116 – 131 . [Google Scholar]) are all accurate, and the gamma approximation is the most accurate.     

Reliability estimation for the exponential distribution

This paper is concerned with classical statistical estimation of the reliability function for the exponential density with unknown mean failure time θ, and with a known and fixed mission time τ. The minimum variance unbiased (MVU) estimator and the maximum likelihood (ML) estimator are reviewed and their mean square errors compared for different sample sizes. These comparisons serve also to extend previous work, and reinforce further the nonexistence of a uniformly best estimator. A class of shrunken estimators is then defined, and it produces a shrunken quasi-estimator and a shrunken estimator. The mean square errors for both these estimators are compared to the mean square errors of the MVU and ML estimators, and the new estimators are found to perform very well. Unfortunately, these estimators are difficult to compute for practical applications. A second class of estimators, which is easy to compute is also developed. Its mean square error properties are compared to the other estimators, and it outperforms all the contending estimators over the high and low reliability parameter space. Since, for all the estimators, analytical mean square error comparisons are not tractable, extensive numerical analyses are done in obtaining both the exact small sample and large sample results.     

New Developments in Statistical Computing: New Bias Evaluation Features of EXPLOR—A Program for Assessing Experimental Design Properties

Longitudinal investigations play an increasingly prominent role in biomedical research. Much of the literature on specifying and fitting linear models for serial measurements uses methods based on the standard multivariate linear model. This article proposes a more flexible approach that permits specification of the expected response as an arbitrary linear function of fixed and time-varying covariates so that mean-value functions can be derived from subject matter considerations rather than methodological constraints. Three families of models for the covariance function are discussed: multivariate, autoregressive, and random effects. Illustrations demonstrate the flexibility and utility of the proposed approach to longitudinal analysis.     

Statistics Problems with Simple Numbers

This article concerns the construction of simple numerical illustrations of statistical techniques for use in introductory classes. Minimizing the amount of calculation facilitates checking, promotes reliability, is quicker, and reinforces the confidence of the student. Methods are described for generating (a) samples of size 3 upwards with integer-valued means and standard deviations, and (b) simple linear regressions with integer-valued intercepts and integer-valued or simple fractional slopes. Extensions to give exact pooled standard deviations in the two-sample problem and simple exact fractional correlation coefficients are also indicated. Further statistical procedures amenable to the same general approach are listed.     

A structured framework for assessing sensitivity to missing data assumptions in longitudinal clinical trials

The objective of this research was to demonstrate a framework for drawing inference from sensitivity analyses of incomplete longitudinal clinical trial data via a re‐analysis of data from a confirmatory clinical trial in depression. A likelihood‐based approach that assumed missing at random (MAR) was the primary analysis. Robustness to departure from MAR was assessed by comparing the primary result to those from a series of analyses that employed varying missing not at random (MNAR) assumptions (selection models, pattern mixture models and shared parameter models) and to MAR methods that used inclusive models. The key sensitivity analysis used multiple imputation assuming that after dropout the trajectory of drug‐treated patients was that of placebo treated patients with a similar outcome history (placebo multiple imputation). This result was used as the worst reasonable case to define the lower limit of plausible values for the treatment contrast. The endpoint contrast from the primary analysis was ? 2.79 (p = .013). In placebo multiple imputation, the result was ? 2.17. Results from the other sensitivity analyses ranged from ? 2.21 to ? 3.87 and were symmetrically distributed around the primary result. Hence, no clear evidence of bias from missing not at random data was found. In the worst reasonable case scenario, the treatment effect was 80% of the magnitude of the primary result. Therefore, it was concluded that a treatment effect existed. The structured sensitivity framework of using a worst reasonable case result based on a controlled imputation approach with transparent and debatable assumptions supplemented a series of plausible alternative models under varying assumptions was useful in this specific situation and holds promise as a generally useful framework. Copyright © 2012 John Wiley & Sons, Ltd.     

Communicating Geographical Risks in Crisis Management: The Need for Research

In any crisis, there is a great deal of uncertainty, often geographical uncertainty or, more precisely, spatiotemporal uncertainty. Examples include the spread of contamination from an industrial accident, drifting volcanic ash, and the path of a hurricane. Estimating spatiotemporal probabilities is usually a difficult task, but that is not our primary concern. Rather, we ask how analysts can communicate spatiotemporal uncertainty to those handling the crisis. We comment on the somewhat limited literature on the representation of spatial uncertainty on maps. We note that many cognitive issues arise and that the potential for confusion is high. We note that in the early stages of handling a crisis, the uncertainties involved may be deep, i.e., difficult or impossible to quantify in the time available. In such circumstance, we suggest the idea of presenting multiple scenarios.