Activities and social contact as antecedents to sleep onset time in U.S. adolescents

This study evaluated adolescents' evening patterns in activities, social contact, and location to better understand antecedents to adolescents' sleep onset time (SOT). The SOT is important for sleep duration and related health outcomes. Using a nationally representative sample of 15- to 18-year-old adolescents from the American Time Use Survey (N = 10,341; 47% female; 57% white), structural equation modeling demonstrated that late SOTs mediated links between evening activities, social contact, locations, and shorter sleep durations. Passive leisure, time in public locations, and time with friends late in the evenings were associated with later SOTs, whereas homework and active leisure did not. Parents and practitioners can use this information to carefully evaluate evening activities, social contact, and location to support healthy SOTs for adolescents across time.     

A GOAL PROGRAMMING MODEL FOR ALLOCATING HUMAN RESOURCES FOR THE GOOD LABORATORY PRACTICE REGULATIONS

The Food and Drug Administration's final Good Laboratory Practice regulation will have a far-reaching effect on testing laboratories that are conducting nonclinical laboratory safety tests. This paper develops a goal programming decision model suitable for setting objectives, meeting budgetary and operational constraints, planning personnel utilization, and evaluating different proposals for allocating laboratory personnel to implement a program.