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501.
The impact of the changes in the gender composition of friendship networks during early adolescence on substance use in late adolescence was examined. The hypothesis was that initial level and increase in the proportion of other‐sex friends in the network would be associated with higher levels of substance use among girls, but not among boys. Girls and boys (n=390) were interviewed annually from ages 12 to 18 (79% retention). For both boys and girls, initial level in the proportion of other‐sex friends predicted alcohol use in late adolescence, whereas it was predictive of drug use in girls only. Moreover, for girls only, a faster increase in the proportion of other‐sex friends in the network predicted later use of alcohol and drugs.  相似文献   
502.
This paper investigates the monetary policy reaction functions of the Central Bank of Republic of Turkey (CBRT) over the periods 1987:01–2001:12 and 2002:01–2009:05. We specifically attempt to shed light on question to what extent exchange rate developments still continue to influence monetary policy, even under inflation targeting. This study seeks to investigate how the monetary policy responded to the exchange rate shocks before and after adoption of inflation targeting regime. How large the effect of exchange rate shocks is accounted for in forecast error variances decompositions for monetary policy as compared to other shocks? Using the VAR model, this study shows that there has been strong pass-through during whole period. Moreover, in the postcrisis period, exchange rate has been the main reaction variable for the CBRT.  相似文献   
503.
This paper is concerned with the pile-up model defined as a nonlinear transformation of a distribution of interest. An observation of the pile-up model is the minimum of a random number of independent variables from the distribution of interest. One specific pile-up model is encountered in time-resolved fluorescence where only the first photon of a random number of photons is observed. In the first part of the paper the Cramér-Rao bound is studied to optimize the experimental conditions by choosing the best tuning parameter which is the average number of variables over which the minimum is taken. The implication is that the tuning parameter currently used in fluorescence does not minimize the acquisition time. However, data obtained at the optimal choice of the tuning parameter require an estimator adapted to the pile-up effect, therefore, an appropriate Gibbs sampler is presented. The covariance matrix of this estimator turns out to be close to the Cramér-Rao bound and hence the acquisition time may be reduced considerably.  相似文献   
504.
Invasive aspergillosis (IA) is a major cause of mortality in immunocompromized hosts, most often consecutive to the inhalation of spores of Aspergillus. However, the relationship between Aspergillus concentration in the air and probability of IA is not quantitatively known. In this study, this relationship was examined in a murine model of IA. Immunosuppressed Balb/c mice were exposed for 60 minutes at day 0 to an aerosol of A. fumigatus spores (Af293 strain). At day 10, IA was assessed in mice by quantitative culture of the lungs and galactomannan dosage. Fifteen separate nebulizations with varying spore concentrations were performed. Rates of IA ranged from 0% to 100% according to spore concentrations. The dose‐response relationship between probability of infection and spore exposure was approximated using the exponential model and the more flexible beta‐Poisson model. Prior distributions of the parameters of the models were proposed then updated with data in a Bayesian framework. Both models yielded close median dose‐responses of the posterior distributions for the main parameter of the model, but with different dispersions, either when the exposure dose was the concentration in the nebulized suspension or was the estimated quantity of spores inhaled by a mouse during the experiment. The median quantity of inhaled spores that infected 50% of mice was estimated at 1.8 × 104 and 3.2 × 104 viable spores in the exponential and beta‐Poisson models, respectively. This study provides dose‐response parameters for quantitative assessment of the relationship between airborne exposure to the reference A. fumigatus strain and probability of IA in immunocompromized hosts.  相似文献   
505.
Video Lottery Terminals (VLT) are associated with pathological gambling and with most of the requests for help in combating gambling addiction. Embeddedness of a person in his or her social network is among the communicational factors that may help explain this phenomenon. To verify this, we compared ego networks of VLT gamblers, of gamblers of games with low request for help and of VLT gamblers in treatment (n = 90). The networks of regular VLT gamblers are small and dense and offer little social support. Gamblers in treatment also have small networks, but they are less dense, have more components and offer more social support. Networks of gamblers with low requests for assistance are approximately twice the size as those of VLT gamblers, are sparser and offer more companionship. In conclusion, the VLT gambler is not an isolated individual, but rather an individual ‘shut-in’ a small network of tightly knitted relationships.  相似文献   
506.
In this study, the performances of linear regression techniques, which are especially used in clinical chemistry in method comparison studies, are compared via the Monte-Carlo simulation. The regression techniques that take the measurement errors of both dependent and independent variables into account are called Type II regression techniques. In this study, we also compare the performances of Type II and Type I (classical regression techniques that do not take the measurement errors of the independent variable into account) regression techniques for different sample sizes and different shape parameters of the Weibull distribution. The mean square error is used as a performance criterion of each technique. MATLAB 7.02 software is used in the simulation study. As a result, in all conditions, the ordinary least-square (OLS)-bisector regression technique, which bisects the OLS(Y | X) and the OLS(X | Y), shows the best performance.  相似文献   
507.
508.
The minimum averaged mean squared error nonparametric adaptive weights use data from m possibly different populations to infer about one population of interest. The definition of these weights is based on the properties of the empirical distribution function. We use the Kaplan-Meier estimate to let the weights accommodate right-censored data and use them to define the weighted Kaplan-Meier estimate. The proposed estimate is smoother than the usual Kaplan-Meier estimate and converges uniformly in probability to the target distribution. Simulations show that the performances of the weighted Kaplan-Meier estimate on finite samples exceed that of the usual Kaplan-Meier estimate. A case study is also presented.  相似文献   
509.
This paper inverts the usual logic of applied optimal income taxation. It starts from the observed distribution of income before and after redistribution and corresponding marginal tax rates. Under a set of simplifying assumptions, it is then possible to recover the social welfare function that would make the observed marginal tax rate schedule optimal. In this framework, the issue of the optimality of an existing tax–benefit system is transformed into the issue of the shape of the social welfare function associated with that system and whether it satisfies elementary properties. This method is applied to the French redistribution system with the interesting implication that the French redistribution authority may appear, under some plausible scenario concerning the size of the labor supply behavioral reactions, non Paretian (e.g. giving negative marginal social weights to the richest class of tax payers).  相似文献   
510.
The weighted likelihood is a generalization of the likelihood designed to borrow strength from similar populations while making minimal assumptions. If the weights are properly chosen, the maximum weighted likelihood estimate may perform better than the maximum likelihood estimate (MLE). In a previous article, the minimum averaged mean squared error (MAMSE) weights are proposed and simulations show that they allow to outperform the MLE in many cases. In this paper, we study the asymptotic properties of the MAMSE weights. In particular, we prove that the MAMSE-weighted mixture of empirical distribution functions converges uniformly to the target distribution and that the maximum weighted likelihood estimate is strongly consistent. A short simulation illustrates the use of bootstrap in this context.  相似文献   
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