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101.
102.
Single-case experiments are frequently used to do research involving a clinical intervention, since large-n trials are often impractical in clinical research. In order to investigate a possible difference in the effect of the treatments considered in the study, nonparametric instruments are valid tools; in particular, permutation solutions work well when we wish to assess differences in treatment effects. We present an extension of a permutation solution to the multivariate response case and to the case of replicated single-case experiments. A simulation study shows that the approach is both reliable under the null hypothesis and powerful under the alternative. At the end, we present the results of an application to two real experiments. 相似文献
103.
Research involving a clinical intervention is normally aimed at testing the treatment effects on a dependent variable, which is assumed to be a relevant indicator of health or quality-of-life status. In much clinical research large-n trials are in fact impractical because the availability of individuals within well-defined categories is limited in this application field. This makes it more and more important to concentrate on single-case experiments. The goal with these is to investigate the presence of a difference in the effect of the treatments considered in the study. In this setting, valid inference generally cannot be made using the parametric statistical procedures that are typically used for the analysis of clinical trials and other large-n designs. Hence, nonparametric tools can be a valid alternative to analyze this kind of data. We propose a permutation solution to assess treatment effects in single-case experiments within alternation designs. An extension to the case of more than two treatments is also presented. A simulation study shows that the approach is both reliable under the null hypothesis and powerful under the alternative, and that it improves the performance of a considered competitor. In the end, we present the results of a real case application. 相似文献
104.
This article enlarges the covariance configurations, on which the classical linear discriminant analysis is based, by considering the four models arising from the spectral decomposition when eigenvalues and/or eigenvectors matrices are allowed to vary or not between groups. As in the classical approach, the assessment of these configurations is accomplished via a test on the training set. The discrimination rule is then built upon the configuration provided by the test, considering or not the unlabeled data. Numerical experiments, on simulated and real data, have been performed to evaluate the gain of our proposal with respect to the linear discriminant analysis. 相似文献
105.
This work stems from the idea of describing the scientific productivity of Italian statisticians. There are several problems that must be addressed in achieving this goal: What data should be used? Have the data been cleaned? What techniques can be used? We propose the use of multiple sources and multiple metrics to get a complete information base. We check the correctness of the data using multivariate outlier identification techniques. We appropriately transform the data. We apply robust clustering to verify the existence of homogeneous groups. We suggest the use of forward search to establish a ranking among scholars. The proposed methodology, which, in this case, allowed us to group scholars into four homogeneous groups and sort them according to multidimensional data, can be applied to other similar applications in bibliometrics. 相似文献
106.
Francesca Dominici Scott L. Zeger Giovanni Parmigiani Joanne Katz Parul Christian 《Journal of the Royal Statistical Society. Series C, Applied statistics》2006,55(2):261-280
Summary. Clinical trials of micronutrient supplementation are aimed at reducing the risk of infant mortality by increasing birth weight. Because infant mortality is greatest among the low birth weight (LBW) infants (2500 g or under), an effective intervention increases the birth weight among the smallest babies. The paper defines population and counterfactual parameters for estimating the treatment effects on birth weight and on survival as functions of the percentiles of the birth weight distribution. We use a Bayesian approach with data augmentation to approximate the posterior distributions of the parameters, taking into account uncertainty that is associated with the imputation of the counterfactuals. This approach is particularly suitable for exploring the sensitivity of the results to unverifiable modelling assumptions and other prior beliefs. We estimate that the average causal effect of the treatment on birth weight is 72 g (95% posterior regions 33–110 g) and that this causal effect is largest among the LBW infants. Posterior inferences about average causal effects of the treatment on birth weight are robust to modelling assumptions. However, inferences about causal effects for babies at the tails of the birth weight distribution can be highly sensitive to the unverifiable assumption about the correl-ation between the observed and the counterfactuals birth weights. Among the LBW infants who have a large causal effect of the treatment on birth weight, we estimate that a baby receiving the treatment has 5% less chance of death than if the same baby had received the control. Among the LBW infants, we found weak evidence supporting an additional beneficial effect of the treatment on mortality independent of birth weight. 相似文献
107.
108.
We measured interpersonal perception accuracy by focusing on the relationship between actors’ centrality and their ability to accurately report their social interactions. We used the network measures of actors’ betweenness centrality and degree centrality to identify the most prominent members by correlating ego-perception and alter-perception in a “non-reciprocity” type of misalignment. We found a positive correlation between actors’ centrality and their centrality as assessed by senior management, and a negative correlation between actors’ centrality and their accuracy in recalling interactions. Underreporting social interactions may represent a third way of measuring the importance of members and finding the most influential actors. 相似文献
109.
Kristina Engwall Francesca Östberg Gunnel Andersson Tomas Bons Åsa Bringlöv 《European Journal of Social Work》2019,22(6):1025-1037
ABSTRACTResearch shows that children with disabilities are victims of violence and abuse to a higher extent than other children and thus need support from social services. In Sweden, cooperation between two different social services units is required to support children with disabilities in socially vulnerable families. In this study, we have examined the intersection between children and disability in a Swedish social services context from the perspective of childhood studies and disability studies. The reasoning of the two units including the child perspective emerged during focus group interviews based on two vignettes. The results show two different rationalities, which has consequences for the disabled child. In spite of a social policy where the ‘best interests of the child’ are meant to prevail and disabilities are meant to be interpreted as barriers in society, children with disabilities seem to be reduced to individuals who are lacking in ability and competency and who are profoundly victimised by power structures that favour the adult perspective in social services. 相似文献
110.
Political process theories of social movements have relied on a set of oppositions between culture and structure that has limited their capacity to capture the supraindividual, durable, and constraining dimensions of culture. The solution is not to abandon an emphasis on objective political structures in favor of potential insurgents' subjective perceptions of political opportunities, but rather to probe the (objective) resources and constraints generated by the cultural dimensions of political structures. Such a perspective would pay closer attention to the cultural traditions, ideological principles, institutional memories, and political taboos that create and limit political opportunities; and would link the master frames that animate protest to dominant political structures and processes. 相似文献