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91.
Young workers' experiences of their first job form an important stage in the transition from school to work, and the quality of that experience is likely to have a strong bearing on future chances in the labour market. We provide evidence on a key aspect of that experience, namely, whether the skills acquired during the first job are firm-specific or in some degree transferable. More than one in six young people acquired only firm-specific skills in their first substantial job. High levels of prior human capital, short training spells or training leading to qualifications tend to raise, while being in casual or temporary jobs tends to lower, the likelihood that transferable skills are acquired.  相似文献   
92.
Superiority claims for improved efficacy are the backbone of clinical development of new therapies. However, not every new therapy in development allows for such a claim. Some therapies per se do not try to improve efficacy further but concentrate on important aspects in safety or convenience. Such improvements can be equally important to patients, and development strategies should be available for such compounds. A three-arm design with placebo, active control and experimental treatment may be viewed as the golden standard for such compounds; however, it may be difficult if not impossible to add a placebo arm in certain diseases. In such situations, non-inferiority designs are the only development option left. This paper will highlight some of the key issues with such designs in practice and will report experience from two studies from different therapeutic areas intended for regulatory submission.  相似文献   
93.
This paper advances contemporary gendered analyses of entrepreneurial activity by exploring self‐employment amongst gay men and lesbian women. Within current entrepreneurial debate, heterosexual women have become the visible embodiment of the gendered subject. Our contribution is to queer this assumption when focusing upon the entrepreneurial activity of gays and lesbians. Our core question investigates if ‘there is evidence of differences between homosexuals and heterosexuals in their likelihood of being entrepreneurially active’. To address this question, we contrast competing notions of gender stereotypes and discrimination whilst drawing on findings from a large‐scale population‐based study of 163,000 UK adults. We find few differences between homosexuals and heterosexuals; this persists after examining intersectional patterns and considering if gay and lesbian entrepreneurs choose particular sectors, geographies or forms of self‐employment. As our discussion highlights, the value of this study lies within its critique of contemporary analyses of gender which assume it is an end‐point rather than a foundation for analysing gender as a multiplicity.  相似文献   
94.
The present study examines the struggle for hegemony in the public sphere by two different systems, following Hong Kong’s handover to China in 1997. It has been postulated that the new media, particularly social media, has become an important public sphere for the citizens of Hong Kong to engage in an anti-hegemonic struggle against China’s discursive encroachment into Hong Kong since 1997. Given that the public platform provided by legacy media has been bought out or coopted by China, new media has begun to serve as a subaltern public sphere to enable resisting the hegemony imposed by China. This was analyzed through a survey conducted as part of this study, which showed that people who are young, read the Apple Daily, have high expectations of local autonomy, and a high regard for press freedom are prone to using social media to obtain their social and political information. This article analyzes the implications of the emergence of a counter-China hegemonic public sphere.  相似文献   
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In this paper, we investigate Bayesian generalized nonlinear mixed‐effects (NLME) regression models for zero‐inflated longitudinal count data. The methodology is motivated by and applied to colony forming unit (CFU) counts in extended bactericidal activity tuberculosis (TB) trials. Furthermore, for model comparisons, we present a generalized method for calculating the marginal likelihoods required to determine Bayes factors. A simulation study shows that the proposed zero‐inflated negative binomial regression model has good accuracy, precision, and credibility interval coverage. In contrast, conventional normal NLME regression models applied to log‐transformed count data, which handle zero counts as left censored values, may yield credibility intervals that undercover the true bactericidal activity of anti‐TB drugs. We therefore recommend that zero‐inflated NLME regression models should be fitted to CFU count on the original scale, as an alternative to conventional normal NLME regression models on the logarithmic scale.  相似文献   
97.
The gendered subjectivities of high achieving school pupils are examined, demonstrating the uneasy relationship between high educational achievement and peer popularity. Drawing on data from a study involving classroom observation and interviews with 71 high-achieving pupils across nine secondary schools in England, the article focuses on the gendered construction of The Boffin. Judith Butler's work, and Hannah Arendt's conception of pariahs and parvenus, are applied to analyse The Boffin as pariah, and as 'queer' in the classroom. The article explores the ways in which this construction is gendered, and the consequences of its application for girls and boys. It is argued that application of this stigmatised term functioned as a powerful deterrent to 'excessive' performances of achievement, for all pupils. But the risks are particularly acute for boys, to whom the 'naming' of Boffin appeared more readily applied, and for whom marginalization as Boffin appears especially perilous (risking particularly pernicious forms of punishment at the hands of other boys).  相似文献   
98.
The Balint groups named after Michael and Enid Balint exist since over 50 years as a well-established method to help general practitioners in understanding and analysing – with the emphasis on the patients - their doctor-patient relationships. Over the years other occupational groups from the psycho-social fields have used and are till this day still using and profiting in a lasting and sustainable manner from this method. In recent times Balint groups have made themselves available to professionals from the widespread and diverse fields of the advisory professions and for management. In the framework of this contribution I would like to discuss the aims of Balint groups as well as the possible benefits of the Balint group method for advisory professions and management. The author - who is himself a medical doctor and a Balint group leader, of doctors as well as from persons working in advisory profession and management - shows several parallels between these professional groups and illustrate the significances of the method for the one profession as well as for the other.  相似文献   
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