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31.
A practical problem with large scale survey data is the potential for overdispersion. Overdispersion occurs when the data display more variability than is predicted by the variance–mean relationship for the assumed sampling model. This paper describes a simple strategy for detecting and adjusting for overdispersion in large scale survey data. The method is primarily motivated by data on the relationship between social class and educational attainment obtained from a 2% sample from the 1991 census of the population of Great Britain. Overdispersion can be detected by first grouping the data into a number of strata of approximately equal size. Under the assumption that the observations are independent and there is no variability in the parameter of interest, there is a direct relationship between the nominal standard errors and the empirical or sample standard deviation of the parameter estimates obtained from each of the separate strata. With the 2% sample from the British census data, quite a discernible departure from this relationship was found, indicating overdispersion. After allowing for overdispersion, improved and more realistic measures of precision of the strength of the social class–education associations were obtained.  相似文献   
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via e-mail: paul.garrett{at}nottingham.ac.uk Summary Harry Ferguson (2001), referring largely to Britain and Ireland,maintains that social work should be committed to a ‘newway of thinking’ which is rooted in ‘life politics’.This idea, uncritically grounded in the ideas of Anthony Giddensand Ulrich Beck, fails to convince because: the assertion thatwe are now living in a ‘post traditional order’is undermined by the resilience of key historical forms of regulationand control which continue, for example, to limit women's choicein the sphere of reproductive rights; identified changes inthe texture of family relations are not evidenced by research;the ‘life politics’ perspective places too greatan emphasis on human agency, choice and volition and not enoughon structural constraint; the structural location of the ‘lifepolitics’ proponents is not interrogated; the analysisis too stridently dismissive of the idea that ‘emancipatorypolitics’ should be social work's primary orientation.  相似文献   
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Carnosine (beta-alanyl-L-histidine) has recently attracted much attention as a naturally occurring antioxidant and transition-metal ion sequestering agent. It has also been shown to act as an anti-glycating agent, inhibiting the formation of advanced glycation end products (AGEs). Through its distinctive combination of antioxidant and antiglycating properties, carnosine is able to attenuate cellular oxidative stress and can inhibit the intracellular formation of reactive oxygen species and reactive nitrogen species. By controlling oxidative stress, suppressing glycation, and chelating metal ions, carnosine is able to reduce harmful sequelae such as DNA damage. AGEs are known contributors to the pathology of Alzheimer's disease, and carnosine therefore merits serious attention as a possible therapeutic agent.  相似文献   
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To explore how parental socialization of emotion may influence children's emotion understanding, which then guides children's interpretations of emotion‐related situations across contexts, we examined the pathways between socialization of emotion and children's adjustment in the classroom, with children's emotion understanding as an intervening variable. Specifically, children's emotion understanding was examined as a mediator of associations between mothers' beliefs about the value and danger of children's emotions and children's adjustment in the classroom within an SEM framework. Classroom adjustment was estimated as a latent variable and included social, emotional, and behavioral indices. Covariates included maternal education, and child gender and ethnicity. Participants were a diverse group of 201 third‐graders (116 African American, 81 European American, 4 Biracial; 48.8% female), their mothers, and teachers. Results revealed that emotion‐related beliefs (value and danger) had no direct influence on classroom adjustment. However, children whose mothers endorsed the belief that emotions are dangerous demonstrated less emotion understanding and were less well‐adjusted in the classroom. Mothers' belief that emotions are valuable was not independently associated with emotion understanding. Findings point to the important role of emotion understanding in children's development across contexts (family, classroom) and developmental domains (social, emotional, behavioral) during the middle childhood years.  相似文献   
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ABSTRACT

Based on a review of the critical literature, the article provides readers with an overview of neoliberalism’s main dimensions. In this sense, it furnishes an accessible conceptual foundation for a number of the articles in the themed issue. It is suggested that those seeking to comprehend neoliberalism should take into account six intermeshed facets: the overturning of ‘embedded liberalism’; the re-configuration of the state in order to better serve the interests of capital; new patterns of income and wealth distribution to benefit the rich and super-rich; insecurity and precariousness; the rise in mass incarceration; a strategic pragmatism. The article briefly dwells on the capitalist crisis which began in 2007 and goes on to suggest that we may be witnessing the emergence of what is termed ‘rhetorically recalibrated neoliberalism’ (RRN).  相似文献   
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Contextual, mother‐, child‐, and father‐level variables were examined in association with fathers' emotion talk to infants during a shared picture book activity, in an ethnically diverse, low‐income sample (N = 549). Significant main effects included the rate of emotion talk from fathers' romantic partners (i.e., the infant's mother), infant attention and distress, and sensitive parenting. Significant interactions were also found. Higher income African American fathers referred to negative emotions more than non‐African American higher income fathers. In addition, African American fathers who demonstrated more negative and intrusive parenting referred to positive emotions more than non‐African American fathers who demonstrated negative and intrusive parenting. Our findings support family systems theory and, specifically, the interdependence of individuals' behaviors within the family unit. Interaction effects are discussed with respect to cultural variation in beliefs about parenting behaviors and the cultural experience of African Americans, including the Black cultural experience and the minority experience.  相似文献   
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This paper critically examines the government's proposals for the reform of services for children in public care, or 'looked after', in England and, more specifically, the proposal to set up Social Work Practices (SWPs, see Note 1 ). These are envisaged as groups of social workers, commissioned by but independent of local authorities. The changes have been mapped out by a Green Paper Care Matters: Transforming the Lives of Children and Young People in Care published in October 2006, a subsequent working group report, and Care Matters: Time for Change , a White Paper published in June 2007. This was followed, in November, by the publication of the Children and Young Persons' Bill. It is argued that there are, at least, two issues which could be focused on by those seeking to counter moves to introduce SWPs. First, the enhanced role being given to private sector providers because, it is maintained, public services provided by local authorities are unambiguously 'failing' children. Second, the fact that the views of parents and 'looked after' children are mostly excluded from the dominant and 'official' discourse on SWPs.  相似文献   
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Summary. Genome-wide measurement of gene expression is a promising approach to the identification of subclasses of cancer that are currently not differentiable, but potentially biologically heterogeneous. This type of molecular classification gives hope for highly individualized and more effective prognosis and treatment of cancer. Statistically, the analysis of gene expression data from unclassified tumours is a complex hypothesis-generating activity, involving data exploration, modelling and expert elicitation. We propose a modelling framework that can be used to inform and organize the development of exploratory tools for classification. Our framework uses latent categories to provide both a statistical definition of differential expression and a precise, experiment-independent, definition of a molecular profile. It also generates natural similarity measures for traditional clustering and gives probabilistic statements about the assignment of tumours to molecular profiles.  相似文献   
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