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161.
During the last decade, a great deal of news media attention has focused on informing the American public about scientific findings on global warming (GW). Has learning this sort of information led the American public to become more concerned about GW? Using data from two surveys of nationally representative samples of American adults, this article shows that the relation between self‐reported knowledge and concern about GW is more complex than what previous research has suggested. Among people who trust scientists to provide reliable information about the environment and among Democrats and Independents, increased knowledge has been associated with increased concern. But among people who are skeptical about scientists and among Republicans more knowledge was generally not associated with greater concern. The association of knowledge with concern among Democrats and Independents who trust scientists was mediated by perceptions of consensus among scientists about GW's existence and by perceptions that humans are a principal cause of GW. Moreover, additional analyses of panel survey data produced findings consistent with the notion that more knowledge yields more concern among Democrats and Independents, but not among Republicans. Thus, when studying the relation of knowledge and concern, it is important to take into account the content of the information that different types of people acquire and choose to rely upon.  相似文献   
162.
Can incentives be effective in encouraging the development of good habits? We investigate the post‐intervention effects of paying people to attend a gym a number of times during one month. In two studies we find marked attendance increases after the intervention relative to attendance changes for the respective control groups. This is entirely driven by people who did not previously attend the gym on a regular basis. In our second study, we find improvements on health indicators such as weight, waist size, and pulse rate, suggesting the intervention led to a net increase in total physical activity rather than to a substitution away from nonincentivized ones. We argue that there is scope for financial intervention in habit formation, particularly in the area of health.  相似文献   
163.
This paper applies some general concepts in decision theory to a linear panel data model. A simple version of the model is an autoregression with a separate intercept for each unit in the cross section, with errors that are independent and identically distributed with a normal distribution. There is a parameter of interest γ and a nuisance parameter τ, a N×K matrix, where N is the cross‐section sample size. The focus is on dealing with the incidental parameters problem created by a potentially high‐dimension nuisance parameter. We adopt a “fixed‐effects” approach that seeks to protect against any sequence of incidental parameters. We transform τ to (δ, ρ, ω), where δ is a J×K matrix of coefficients from the least‐squares projection of τ on a N×J matrix x of strictly exogenous variables, ρ is a K×K symmetric, positive semidefinite matrix obtained from the residual sums of squares and cross‐products in the projection of τ on x, and ω is a (NJ) ×K matrix whose columns are orthogonal and have unit length. The model is invariant under the actions of a group on the sample space and the parameter space, and we find a maximal invariant statistic. The distribution of the maximal invariant statistic does not depend upon ω. There is a unique invariant distribution for ω. We use this invariant distribution as a prior distribution to obtain an integrated likelihood function. It depends upon the observation only through the maximal invariant statistic. We use the maximal invariant statistic to construct a marginal likelihood function, so we can eliminate ω by integration with respect to the invariant prior distribution or by working with the marginal likelihood function. The two approaches coincide. Decision rules based on the invariant distribution for ω have a minimax property. Given a loss function that does not depend upon ω and given a prior distribution for (γ, δ, ρ), we show how to minimize the average—with respect to the prior distribution for (γ, δ, ρ)—of the maximum risk, where the maximum is with respect to ω. There is a family of prior distributions for (δ, ρ) that leads to a simple closed form for the integrated likelihood function. This integrated likelihood function coincides with the likelihood function for a normal, correlated random‐effects model. Under random sampling, the corresponding quasi maximum likelihood estimator is consistent for γ as N→∞, with a standard limiting distribution. The limit results do not require normality or homoskedasticity (conditional on x) assumptions.  相似文献   
164.
Technologies such as radio‐frequency identification and global positioning systems can provide improved real‐time tracking information for products and replenishment orders along the supply chain. We call this type of visibility order progress information. In this paper, we investigate how order progress information can be used to improve inventory replenishment decisions. To this end, we examine a retailer facing a stochastic lead time for order fulfillment. We characterize a replenishment policy that is based on the classical (Q, R) policy and that allows for releasing emergency orders in response to the order progress information. We show that the optimal structure of this policy is given by a sequence of threshold values dependent on order progress information. In a numerical study we evaluate the cost savings due to this improved replenishment policy.  相似文献   
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The increase in religious diversity produced by the global movement of people and cultures and the proliferation of internal difference within religious communities raises social policy issues. Consideration of these issues is facilitated by understanding that religious groups intersect with social policy in four basic ways: as objects, sources, critics and implementers of policy. A major issue is the challenge societies face in respecting freedoms of religion and belief on the one hand and providing services to all citizens on the other. Resolving these issues requires an awareness of the religious profile of a society and sensitivity to its religious diversity and to the ways services are delivered. Research into the current status of freedom of religion and belief in Australia is used as a case study to identify issues and potential ways to address them. This research reveals that there is a lack of mechanisms for considering and resolving these issues.  相似文献   
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Despite advances in clinical trial design, failure rates near 80% in phase 2 and 50% in phase 3 have recently been reported. The challenges to successful drug development are particularly acute in central nervous system trials such as for pain, schizophrenia, mania, and depression because high‐placebo response rates lessen assay sensitivity, diminish estimated treatment effect sizes, and thereby decrease statistical power. This paper addresses the importance of rigorous patient selection in major depressive disorder trials through an enhanced enrichment paradigm. This approach led to a redefinition of an ongoing, blinded phase 3 trial algorithm for patient inclusion (1) to eliminate further randomization of transient placebo responders and (2) to exclude previously randomized transient responders from the primary analysis of the double blind phase of the trial. It is illustrated for a case study for the comparison between brexpiprazole + antidepressant therapy and placebo + antidepressant therapy. Analysis of the primary endpoint showed that efficacy of brexpiprazole versus placebo could not be established statistically if the original algorithm for identification of placebo responders was used, but the enhanced enrichment approach did statistically demonstrate efficacy. Additionally, the enhanced enrichment approach identified a target population with a clinically meaningful treatment effect. Through its successful identification of a target population, the innovative enhanced enrichment approach enabled the demonstration of a positive treatment effect in a very challenging area of depression research.  相似文献   
170.
ABSTRACT

The purpose of this groundbreaking study was to evaluate outcomes of 482 LGBTQ (lesbian, gay, bisexual, transgender, or questioning) youth and young adults who received services and supports through the Comprehensive Community Mental Health Services for Children with Serious Emotional Disturbances Program (CMHI). This study was a secondary data analysis using data from a larger study of 3208 LGBTQ and non-LGBTQ youth ages 11 through 21 who had a serious emotional disturbance (SED). This study is significant in that it evaluates functional outcomes for young people identified as LGBTQ based on a specialized service framework (i.e., system of care approach). In essence, do LGBTQ youth with SED benefit from a specific approach to intervention? In addition, a comparison at intake on suicidality, bullying and victimization was conducted between the LGBTQ and non-LGBTQ identifying youth from the larger sample. The youth and a caregiver were interviewed face-to-face separately at intake, 6-months, and 12-months. Significant improvements were found across all of the dependent variables, supporting the viability of SOC for improving outcomes for LGBTQ youth. Future research should continue to build on this study by adding to the design a control group to improve internal validity of the findings.  相似文献   
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