Medical laboratory diagnostics and statistics

We review the statistical contributions to the development and production of laboratory diagnostic assays. The tasks and facets of the role of a statistician in diagnostic industry are discussed.     

Editorial

Ohne Zusammenfassung

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Editorial

     

Infrastructure in Developing and Transition Countries: Risk and Protection

This article examines two possible strategies for financing post-disaster infrastructure rehabilitation in developing and transition countries: relying on ex ante financing instruments (including insurance, catastrophe bonds, and other risk-transfer instruments) and ex post borrowing or credit. Insurance and other ex ante instruments will increase a country's stability, especially if the government authorities have a difficult time borrowing or otherwise raising funds after a major disaster; however, these instruments have an opportunity cost and can reduce the country's economic growth potential. The cost-benefit tradeoff is therefore one between economic growth through infrastructure investment and added solvency and stability for the economy. This article develops a model to illustrate this tradeoff. The model, which views the infrastructure of a developing or transition country as a nondiversifiable portfolio that generates returns, can provide a basis for evaluating alternative financing options depending on the country's objectives in terms of growth, solvency, and stability.     

黑格尔法哲学与德里达《法规的力量》比较

把黑格尔与德里达进行对照,我们会发现：黑格尔思考的是法的自由原则,在这个原则上能够有法的建筑。而德里达在公正和暴力之间的张力区域中理解法,那里不可能有建构,而只有解构。面对西方传统和当代思想我们自身如何能够占据一个区别于后现代的立场？当代思想的整体性区分已经为我们打开对人性的居住的记忆。     

Replik zu den Erwiderungen zu den Anmerkungen zu den Determinanten der Pr��fungshonorare in Deutschland

I maintain my critique of the studies of Bigus and Zimmermann (2009) and of Köhler et al. (2010) without reservation. In light of the legal basis of the scope of audits of financial statements, of auditing standards, of the practice of auditing of international groups of companies, and of international studies of audit fees, the replies of the authors do not provide solid counter arguments and do not seem to take the practice of auditing into account.     

Dependency of Crop Production between Global Breadbaskets: A Copula Approach for the Assessment of Global and Regional Risk Pools

As recent events have shown, simultaneous crop losses in different parts of the world can cause serious risks to global food security. However, to date, little is known about the spatial dependency of lower than expected crop yields from global breadbaskets. This especially applies in the case of extreme events, i.e., where one or more breadbaskets are experiencing far below average yields. Without such information, risk management approaches cannot be applied and vulnerability to extremes may remain high or even increase in the future around the world. We tackle both issues from an empirical perspective focusing on wheat yield. Interdependencies between historically observed wheat yield deviations in five breadbaskets (United States, Argentina, India, China, and Australia) are estimated via copula approaches that can incorporate increasing tail dependencies. In doing so, we are able to attach probabilities to interregional as well as global yield losses. To address the robustness of our results, we apply three different methods for constructing multivariate copulas: vine copulas, ordered coupling using a minimax approach, and hierarchical structuring. We found interdependencies between states within breadbaskets that led us to the conclusion that risk pooling for extremes is less favorable on the regional level. However, notwithstanding evidence of global climatic teleconnections that may influence crop production, we also demonstrate empirically that wheat production losses are independent between global breadbaskets, which strengthens the case for interregional risk pooling strategies. We argue that through interregional risk pooling, postdisaster liabilities of governments and international donors could be decreased.     

Asymptotically optimal rank tests for the two-sample problem with randomly censored data

Using the methods of asymptotic decision theory asymptotically optimal rank tests are constructed in the two-sample testing problem for translation families and positive scale families under the assumption of equal censoring in both samples. The resulting tests have a simple form extending the known tests for un-censored data in a natural way. Relations to a recent proposal by Albers and Akritas are discussed.