Membranes, mitochondria and amoebae: shape models

Most real-world shapes and images are characterized by high variability- they are not rigid, like crystals, for example—but they are strongly structured. Therefore, a fundamental task in the understanding and analysis of such image ensembles is the construction of models that incorporate both variability and structure in a mathematically precise way. The global shape models introduced in Grenander's general pattern theory are intended to do this. In this paper, we describe the representation of two-dimensional mitochondria and membranes in electron microscope photographs, and three-dimensional amoebae in optical sectioning microscopy. There are three kinds of variability to all of these patterns, which these representations accommodate. The first is the variability in shape and viewing orientation. For this, the typical structure is represented via linear, circular and spherical templates, with the variability accomodated via the application of transformations applied to the templates. The transformations form groups: scale, rotation and translation. They are locally applied throughout the continuum and of high dimension. The second is the textural variability; the inside and outside of these basic shapes are subject to random variation, as well as sensor noise. For this, statistical sensor models and Markov random field texture models are used to connect the constituent structures of the shapes to the measured data. The third variability type is associated with the fact that each scene is made up of a variable number of shapes; this number is not assumed to be known a priori. Each scene has a variable number of parameters encoding the transformations of the templates appropriate for that scene. For this, a single posterior distribution is defined over the countable union of spaces representing models of varying numbers of shapes. Bayesian inference is performed via computation of the conditional expectation of the parametrically defined shapes under the posterior. These conditional mean estimates are generated using jump-diffusion processes. Results for membranes, mitochondria and amoebae are shown.     

INTERGENERATIONAL MOBILITY IN THE REPUBLIC OF IRELAND: Does Gender Make a Difference?

This article compares in regression models the effects of occupational status of both fathers and mothers simultaneously upon the attainment of men and women in the Irish Republic. The sample matches male respondents from the 1973/1974 Irish Mobility Study with the labour active female sibling next closest in age. Since the analysis compares working siblings and each 'matched pair' shares the same family origin characteristics, the problems attendant upon using a sample originally of men only are partially avoided. The results advance beyond previous research since, rather than separate models by gender, models include parents and children of both genders, allowing direct rather than indirect evaluation of gender-based determinants of occupational attainment. Both fathers and mothers significantly affect children's attainment, in ways that vary by the child's gender. The results highlight the salience of mothers' attainment for their children and question the 'mainstream' model of equivalent mechanisms of occupational attainment for both genders. Models of social mobility that consider men and women as special instances of a general perspective provide the most fruitful approach for further development.     

Case study in the Bayesian analysis of a cost‐effectiveness trial in the evaluation of health care technologies: Depression

We present a case study based on a depression study that will illustrate the use of Bayesian statistics in the economic evaluation of cost‐effectiveness data, demonstrate the benefits of the Bayesian approach (whilst honestly recognizing any deficiencies) with respect to frequentist methods, and provide details of using the methods, including computer code where appropriate. Copyright © 2003 John Wiley & Sons, Ltd.     

Trait Expressiveness and Marital Satisfaction: The Role of Idealization Processes

This study examined the processes that underlie the association between trait expressiveness and marital satisfaction. A total of 168 newlywed couples participated in a four‐wave, 13‐year longitudinal study of marriage. Cross‐sectional and longitudinal path analyses suggested that expressiveness promotes satisfaction by leading spouses to engage in affectionate behavior and by leading them to idealize their partner. Expressive people formed idealized images of their partner because they brought out the best in their partner's behavior and because they interpreted their partner's behavior in a favorable light. The study extends previous research by showing that the benefits of trait expressiveness extend into the second decade of marriage and by providing a plausible explanation of the connections between trait expressiveness and marital satisfaction.     

Accuracy of the College Majors Finder for Three Majors

The Self-Directed Search was administered to 68 university seniors who were majoring in Chemistry/Chemical Engineering, Elementary Education, and Office Administration. Their resulting three-letter summary codes were compared with three-letter college major codes obtained from the College Majors Finder. A high degree of agreement between the two sets of codes was found for each of the three majors. Effective methods for matching people to jobs have held the interest and occupied much time for career counselors and vocational theorists since the inception of the trait-factor approach to career counseling. More recently, Holland (1985a) broadened and clarified matching procedures through the development of his typological theory of vocational choice. Just as personality types and occupational environments have been organized using Holland's framework to foster an understanding of occupational choice, Holland's theory can also be used to explain other types of choices, such as choice of a college major.     

Immigrants' Language Skills and Visa Category1

This article is concerned with the determinants of English language proficiency among immigrants in a longitudinal survey for Australia. It focuses on both visa category and variables derived from an economic model of the determinants of destination‐language proficiency among immigrants. Skills‐tested and economic immigrants have the greatest proficiency shortly after immigration, followed by family‐based visa recipients, with refugees having the lowest proficiency. Other variables the same, these differences disappear by 3.5 years after immigration for speaking skills; and although they diminish, they persist longer for reading and writing skills. The variables generated from the model of destination‐language proficiency (such as schooling and age at migration) are, in part, predictions of visa category, but they are more important statistically for explaining proficiency.     

The government, the market, and the problem of catastrophic loss

This article addresses the comparative advantage of the government to the private property/casualty insurance industry for the provision of insurance coverage for catastrophic losses. That the government can play an important role as an insurer of societal losses has been a central public policy principle since at least the New Deal. In addition, our government typically automatically provides forms of specific relief following unusually severe or unexpected disasters, which itself can be viewed as a form of ex post insurance. This article argues that, for systemic reasons, the government is much less effective than the private property/casualty insurance market in providing coverage of losses generally, but especially of losses in contexts of catastrophes.     

The merton thesis: Oetinger and German Pietism,a significant negative case

The Merton thesis identifies two movements — English Puritanism and German Pietism — as causally significant in the development of the scientific revolution of the 17th and 18th centuries. It attributes this connection to a strong compatibility between the values of ascetic Protestantism and those associated with modern science. This article questions Merton's conclusion regarding one of these movements, German Pietism, by arguing that the Pietist ethos stood in sharp conflict with what Merton has called the normative structure of science. One manifestation of this conflict involves Friedrich Oetinger's articulation of a contending religious-mystical conception of science, which assigned a central place to feeling, intuition, the role of the divine, and a qualitative approach to nature. This conception of science, it is argued, provides the clearest indication of the conceptual and valuative distance that tended to separate Pietists from the new science of the 17th and 18th centuries.An earlier version of this article was presented at the 1990 meeting of the Society for the Scientific Study of Religion, in Virginia Beach.