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Despite the cultural specificity of aspects of attachment theory (Layton, 2006 Layton , L. ( 2006 ). Racial identities, racial enactments, and normative unconscious processes . Psychoanalytic Quarterly , 75 , 237269 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]) it remains influential. Disorganized attachment and the alien self are linked to borderline phenomena and attacks upon the body (Fonagy et al., 2002 Fonagy , P. , Gergely , G. , Jurist , E. , & Target , M. ( 2002 ). Affect Regulation, Mentalization and the Development of the Self . New York , NY : Other Press . [Google Scholar]), including sexual attacks (Straker, 2002 Straker , G. ( 2002 ). Being in two minds: The psychodynamics of paedophilia. In Australian Psychoanalytic Society annual conference, July, Melbourne, Australia . [Google Scholar]). Recently (Fonagy, 2006 Fonagy , P. ( 2006 ). Psychosexuality and psychoanalysis: An overview . In: Identity, Gender and Sexuality 150 Years After Freud , ed. P. Fonagy , R. Krause , & M. Leuzinger-Bohleber . London , UK : International Psychoanalytical Association , pp. 120 . [Google Scholar], 2008 ——— . ( 2008 ). A genuinely developmental theory of sexual enjoyment and its implications for psychoanalytic technique . Journal of the American Psychoanalytic Association , 56 , 1136 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Target, 2007 Target , M. ( 2007 ). Is our sexuality our own? A developmental model of sexuality based on early affect mirroring . British Journal of Psychotherapy , 23 , 517530 .[Crossref] [Google Scholar]) used the concept of the alien self to explain sexuality in general. This article challenges this extension as it again ignores cultural specificity, presents psychoanalysis as the arbiter of “normal” sexuality, and entrenches heteronormativity. It also lends itself to inadvertently condoning sexual harassment, as evidenced in a case study presented by Fonagy (2008 ——— . ( 2008 ). A genuinely developmental theory of sexual enjoyment and its implications for psychoanalytic technique . Journal of the American Psychoanalytic Association , 56 , 1136 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).  相似文献   
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In earlier work we assembled a database of classical pharmacokinetic parameters (e.g., elimination half-lives; volumes of distribution) in children and adults. These data were then analyzed to define mean differences between adults and children of various age groups. In this article, we first analyze the variability in half-life observations where individual data exist. The major findings are as follows. The age groups defined in the earlier analysis of arithmetic mean data (0-1 week premature; 0-1 week full term; 1 week to 2 months; 2-6 months; 6 months to 2 years; 2-12 years; and 12-18 years) are reasonable for depicting child/adult pharmacokinetic differences, but data for some of the earliest age groups are highly variable. The fraction of individual children's half-lives observed to exceed the adult mean half-life by more than the 3.2-fold uncertainty factor commonly attributed to interindividual pharmacokinetic variability is 27% (16/59) for the 0-1 week age group, and 19% (5/26) in the 1 week to 2 month age group, compared to 0/87 for all the other age groups combined between 2 months and 18 years. Children within specific age groups appear to differ from adults with respect to the amount of variability and the form of the distribution of half-lives across the population. The data indicate departure from simple unimodal distributions, particularly in the 1 week to 2 month age group, suggesting that key developmental steps affecting drug removal tend to occur in that period. Finally, in preparation for age-dependent physiologically-based pharmacokinetic modeling, nationally representative NHANES III data are analyzed for distributions of body size and fat content. The data from about age 3 to age 10 reveal important departures from simple unimodal distributional forms-in the direction suggesting a subpopulation of children that are markedly heavier than those in the major mode. For risk assessment modeling, this means that analysts will need to consider "mixed" distributions (e.g., two or more normal or log-normal modes) in which the proportions of children falling within the major versus highweight/fat modes in the mixture changes as a function of age. Biologically, the most natural interpretation of this is that these subpopulations represent children who have or have not yet received particular signals for change in growth pattern. These apparently distinct subpopulations would be expected to exhibit different disposition of xenobiotics, particularly those that are highly lipophilic and poorly metabolized.  相似文献   
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By June 2021, children and young people had experienced two periods of lockdown and home learning in Northern Ireland. The detrimental impact of these periods of indefinite confinement is wider reaching than reported educational stagnation, with the fundamental rights of childhood: play; rest; and leisure; all adversely implicated. Autistic children's experiences of Covid-19 have been largely absent from current crisis and recovery discourse. This is the first published study to directly and specifically involve autistic children both as research advisors and as research participants in a rights-based participatory study relating to the pandemic. Drawing on concepts of ableist childism and epistemic injustice, this article presents, through Photovoice, the emotional, social and educational experiences of post- primary aged autistic young people in Northern Ireland during the first 2020 lockdown of the Covid-19 pandemic. The project was grounded in a child rights-based approach and was guided by a group of four autistic young advisors aged 11–15. The paper concludes by arguing that government responses to the pandemic, as experienced by autistic young people, act as forms of oppression that prioritises and further embeds normative non-autistic structures and responses under the guise of public health necessity.  相似文献   
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Recent research points to a growing gap between immigrant and native‐born outcomes in the Canadian labour market at the same time as selection processes emphasize recruiting highly educated newcomers. Drawing on interviews with well‐educated men and women who migrated from countries in sub‐Saharan Africa, this paper explores the gendered processes that produce weak economic integration in Canada. Three‐quarters of research participants experienced downward occupational mobility, with the majority employed in low‐skilled, low‐wage, insecure forms of “survival employment”. In a gendered labour market, where common demands for “Canadian experience”, “Canadian credentials” and “Canadian accents” were uneven across different sectors of the labour market, women faced particular difficulties finding “survival employment”; in the long run, however, women’s greater investment in additional post‐secondary education within Canada placed them in a somewhat better position than men. The policy implications of this study are fourfold: first, we raise questions about the efficacy of Canadian immigration policies that prioritize the recruitment of well‐educated immigrants without addressing the multiple barriers that result in deskillling; second, we question government policies and settlement practices that undermine more equitable economic integration of immigrants; third, we address the importance of tackling the “everyday racism” that immigrants experience in the Canadian labour market; and finally, we suggest the need to re‐think narrowly defined notions of economic integration in light of the gendered nature of contemporary labour markets, and immigrants’ own definitions of what constitutes meaningful integration.  相似文献   
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There are concerns for the stability and outcomes for children in care amongst policy makers in England and many other countries. The goal of permanence for children separated from their birth families and in the care of the state has dominated child care policy and practice in the UK, the USA and Canada since the 1980s, but the meanings of permanence in terms of stability, emotional security and family membership into adulthood are complex and the placements and legal status thought best able to achieve permanence are contested.This research was an investigation of planning for permanence in long-term foster family care in England, where it is accepted by policy makers that this is a legitimate permanence option. The aim was to consider the fit between the planning and reviewing systems designed to achieve permanence in foster care and the reality of planned permanent placements as experienced by foster children and foster carers.Results suggested that although committed relationships within the foster family were helping children to feel a sense of permanence and to become part of the family, planning and reviewing procedures required by corporate parenting were often not adapted to the special nature of these foster placements. It was concluded that although planning and reviewing systems need to be rigorous, they also need to be more child and family sensitive in permanent placements.  相似文献   
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