蛋白组学方法应用于人肺癌组织蛋白表达的研究

采用蛋白组学方法,利用4例中国肺癌患者的切除肺癌组织测定了磷癌(SQCLC)的蛋白表达 从双向电泳(2-DEgel)切下53个点,49个蛋白与数据库搜索结果吻合。在鉴定的24个蛋白中,17个蛋白有报道是与肺癌相关的蛋白其7个蛋白与人类其它癌症相关。所建立的蛋白组学方法能够用于建立一种基于组织的化验方法,发现肺癌患者组织中表达的蛋白标记物以用于癌症的分子学诊断。     

唐宋变革论体系的演化

自近代以来，由日本学者构筑的唐宋变革论体系，伴随时代的发展与新的知识资源的扩充，呈现出不断发展变化的趋势。本文旨在揭示这一演化的历史过程，尝试着分析这一过程变动发展的原因，并由此作出区别于以往的评价。     

发展政府与政府的科学发展

在中央提出科学发展观之后，各个领域都面临一个科学发展的问题。政府作为社会治理的主体，在推进科学发展上具有更为重要的作用，因此科学发展观要求政府自身必须首先科学发展。政府的科学发展必然包括政府自身的发展和面向社会治理能力的发展。果有善治则必有善政，因此必须大力发展政府，构建中国特色的发展政府学，借鉴全球发展政府的理论成果，研究中国政府发展的规律，为中国各级政府的改革和全面履行科学发展观职能提供理论及实践指导。     

Implied Preference for Seismic Design Level and Earthquake Insurance

Seismic risk can be reduced by implementing newly developed seismic provisions in design codes. Furthermore, financial protection or enhanced utility and happiness for stakeholders could be gained through the purchase of earthquake insurance. If this is not so, there would be no market for such insurance. However, perceived benefit associated with insurance is not universally shared by stakeholders partly due to their diverse risk attitudes. This study investigates the implied seismic design preference with insurance options for decisionmakers of bounded rationality whose preferences could be adequately represented by the cumulative prospect theory (CPT). The investigation is focused on assessing the sensitivity of the implied seismic design preference with insurance options to model parameters of the CPT and to fair and unfair insurance arrangements. Numerical results suggest that human cognitive limitation and risk perception can affect the implied seismic design preference by the CPT significantly. The mandatory purchase of fair insurance will lead the implied seismic design preference to the optimum design level that is dictated by the minimum expected lifecycle cost rule. Unfair insurance decreases the expected gain as well as its associated variability, which is preferred by risk-averse decisionmakers. The obtained results of the implied preference for the combination of the seismic design level and insurance option suggest that property owners, financial institutions, and municipalities can take advantage of affordable insurance to establish successful seismic risk management strategies.     

1937年上海“纱交风潮”——以《申报》和《大公报》报道为中心的考察

1937年上海“纱交风潮”系上海纱布交易所爆发的影响巨大且后果最严重的一次风潮。此次风潮的起因是多方面的，其中最根本的原因是孔家官僚资本为获取巨利插手纱交、操纵市场、大搞投机活动。这场风潮促使国民政府颁布《取缔上海纱布交易所投机办法》，并对此次风潮进行“澈查”，然“澈查”结果却虎头蛇尾。由此看出，国民政府与官僚资本的密切关系，即官僚资本已凭借各种超经济特权在国民经济中取得了独特的优势地位。     

Non-ignorable missing covariate data in survival analysis: a case-study of an International Breast Cancer Study Group trial

Summary.  Non-ignorable missing data, a serious problem in both clinical trials and observational studies, can lead to biased inferences. Quality-of-life measures have become increasingly popular in clinical trials. However, these measures are often incompletely observed, and investigators may suspect that missing quality-of-life data are likely to be non-ignorable. Although several recent references have addressed missing covariates in survival analysis, they all required the assumption that missingness is at random or that all covariates are discrete. We present a method for estimating the parameters in the Cox proportional hazards model when missing covariates may be non-ignorable and continuous or discrete. Our method is useful in reducing the bias and improving efficiency in the presence of missing data. The methodology clearly specifies assumptions about the missing data mechanism and, through sensitivity analysis, helps investigators to understand the potential effect of missing data on study results.     

论教育的高贵性和神性

在教育已经陷入功利主义的今天,追问教育的真精神不仅是现代教育救赎之必要,也是教育发展之必然。教育的真精神在于教育的高贵性和神性。教育的神性是教育对于提升人性达致“人之为人”的意义的关爱。教育是使人成为人的一种精神性生活方式。教育是“爱”的事业,教育的“爱”出于对存在的虔诚而不是出于加工或塑造的自大和傲慢。     

格式条款法律特征刍议

格式条款是合同法上的重要制度。我国现有合同法论著一般并未将格式条款的构成要件作为一个独立问题加以研究，笔者主要从六个方面分析讨论了格式条款的法律特征，即制订方面的特征、适用范围方面的特征、内容方面的特征、当事人关系方面的特征、形式方面的特征、解释方面的特征。     

Time, Self, and the Curiously Abstract Concept of Agency*

The term "agency" is quite slippery and is used differently depending on the epistemological roots and goals of scholars who employ it. Distressingly, the sociological literature on the concept rarely addresses relevant social psychological research. We take a social behaviorist approach to agency by suggesting that individual temporal orientations are underutilized in conceptualizing this core sociological concept. Different temporal foci—the actor's engaged response to situational circumstances—implicate different forms of agency. This article offers a theoretical model involving four analytical types of agency ("existential,""identity,""pragmatic," and "life course") that are often conflated across treatments of the topic. Each mode of agency overlaps with established social psychological literatures, most notably about the self, enabling scholars to anchor overly abstract treatments of agency within established research literatures.     

Gender and the 'New Paradigm' of Health

This article provides a critical review of literature on the relationship between gender and the 'new paradigm' of health. An overview of the feminist critique of health is given, from the Women's Health Movement of the late 1960s and early feminist debates about medicalisation, to more recent discussions about structural inequalities between men and women, eating disorders, and AIDS. I then go on to explore the feminist response to the so-called 'new paradigm' of health (an approach that emphasises health promotion, individual responsibility for health, and body-monitoring). Arguments that health promotion initiatives target women and confirm their position as principal guardians of health within the family are considered, as well as literature on the breast cancer awareness campaign. I then explore the growing body of literature on masculinity and health, and its account of the relationship between gender and current ideas about healthiness. Finally, I offer up some suggestions for the direction a new feminist critique of health might take.