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121.
Joint Modelling of Recurrent Infections and Antibody Response by Bayesian Data Augmentation 总被引:1,自引:0,他引:1
Mervi Eerola Dario Gasbarra P. Helena Mäkelä Henri Linden rei Andreev 《Scandinavian Journal of Statistics》2003,30(4):677-698
Abstract. A joint dynamic model for the interdependence between infection, immunity and risk of disease is presented. Recurrent latent infections are modelled as realizations from a renewal process and antibody dynamics as a diffusion with a decreasing drift modified by the stimulating effect of the random infections. The augmented submodels are estimated simultaneously in one large Markov chain Monte Carlo algorithm. As an example, we consider the risk of recurrent ear infections when having only partially observed information on bacterial carriage and antibody concentrations. 相似文献
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The aim of this research was to identify continuities/discontinuities in the values of Portuguese mothers with kindergarten children belonging to high and low socio‐cultural backgrounds, mothers from different cultures and kindergarten teachers. The sample was composed of sixty‐five mothers (fourteen Roma, fifteen Indian, twelve African, and ten Portuguese from low socio‐cultural backgrounds, and fourteen Portuguese from middle and high socio‐cultural backgrounds) and fifteen kindergarten teachers, from middle and high socio‐cultural backgrounds. They all worked in multicultural classes, and all were aged between 18 and 45. A list of behaviors and open questions about adaptive/non‐adaptive behaviors and the metaphor of Adaptive Adult were applied to identify their values. Results show continuities and discontinuities in mothers’ and kindergarten teachers’ values. The most important were: (1) valuing of autonomy by the kindergarten teachers and Portuguese mothers from high socio‐economic backgrounds and (2) valuing of conformity by Indian and Roma mothers. Discontinuities were also observed between (1) kindergarten teachers and all groups of mothers concerning personal fulfillment, only valued by kindergarten teachers, (2) professional fulfillment, only valued by Indian mothers, and (3) self characteristics, only valued by Portuguese mothers from a low socio‐economic background. Implications of these results are analyzed with regard to research, the training of kindergarten teachers and the nature of interventions with parents. 相似文献
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Drug overdose mortality and its economic consequences are explored for ten different drug categories in this article. Data on drug overdose mortality in Texas for the years 1980-1986 are examined and a cost of mortality analysis is presented using the human capital methodology. In addition, mortality rates per 100,000 population are presented for each drug category. The results indicate that the cost of drug overdose mortality has more than doubled over the six-year period. The greatest growth in mortality cost has been for narcotics and cocaine, with commonly prescribed psychoactive drugs remaining fairly constant. The results suggest that men are at far greater risk of drug overdose than women with respect to illicit drugs. Women, however, appear to be at greater risk for overdose from commonly prescribed drugs. 相似文献
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Forty people living with multiple sclerosis and/or their families were interviewed to assess their knowledge of, use of, needs for, and attitudes towards support groups. The majority of participants were both misinformed about their illness and ignorant of resources available to them, resulting in much stress and anxiety. It is felt that information-both about their disease condition and of support structures-needs systematically to be available and accessible to patients on diagnosis, and is a necessary component for empowerment. 相似文献
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Reflecting the level of priority currently attributed to public university financing in ongoing discussions, the objective of this article is to debate alternative forms of attracting resources from stakeholders not normally associated with the financing of public universities. We begin by detailing sources of university financing as it slowly migrates from the public sector to the market. After we move on to describe the main public university stakeholders and the respective relationships between the parties. Finally, our discussion focuses on different means and alternatives ways, to finance public universities through use of non-traditional stakeholders giving some examples. In conclusions we find that despite university managers normally being aware of such entities, the other internal university actors show a lack of pro-activeness regarding the opportunities presented by different stakeholders. So the public universities need to actively engage with the marketplace, and this reality can be achieved if at internal level they are assigned priorities for the relationships with these new stakeholders. 相似文献
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