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61.
James Gerard Caillier 《The Social Science Journal》2018,55(2):108-115
Agency theory suggests that when agencies adopt flexible work schedules, employees will be more likely to remain with the organization, because these programs demonstrate that the organization cares about their well-being in that flexible work schedules give them more flexibility regarding when, where, and how they perform their work. To test this proposition, cross-sectional panel data at the agency level were obtained from two federal government sources: Federal Employee Viewpoint Survey and FedScope. Furthermore, transfers and quits were the two forms of turnover examined. After lagging the independent variables behind turnover over several years so as to provide a robust test of causality, the results show only limited support for agency theory. Specifically, teleworking was found to lower quits. However, teleworking was not found to reduce transfers or turnover, in general. Furthermore, alternative work schedules were not found to have an impact on quits, transfers, or turnover generally. 相似文献
62.
Alison L. Antes John T. Chibnall Kari A. Baldwin Raymond C. Tait Jillon S. Vander Wal James M. DuBois 《Accountability in research》2016,23(5):288-308
The professional decision-making in research (PDR) measure was administered to 400 National Institutes of Health (NIH)-funded and industry-funded investigators, along with measures of cynicism, moral disengagement, compliance disengagement, impulsivity, work stressors, knowledge of responsible conduct of research (RCR), and socially desirable response tendencies. Negative associations were found for the PDR and measures of cynicism, moral disengagement, and compliance disengagement, while positive associations were found for the PDR and RCR knowledge and positive urgency, an impulsivity subscale. PDR scores were not related to socially desirable responding, or to measures of work stressors and the remaining impulsivity subscales. In a multivariate logistic regression analysis, lower moral disengagement scores, higher RCR knowledge, and identifying the United States as one’s nation of origin emerged as key predictors of stronger performance on the PDR. The implications of these findings for understanding the measurement of decision-making in research and future directions for research and RCR education are discussed. 相似文献
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James E. Brooks 《Marriage & Family Review》2017,53(4):347-364
The current study used dyadic data to investigate the impact of relationship type and social support on the retrospective accounts of commitment trajectories of romantic relationships. Past research suggests that social support is a positive contributor to relationship stability and commitment, which may be especially true for partners in interracial relationships who face broader societal opposition than intraracial couples. Using multilevel modeling, we investigated the effects of sex, relationship type, and social support on reports of commitment. Results showed differences in trajectories of commitment based on couple type (interracial vs. intraracial) for both men and women. Social support was found to have an especially strong impact for women in interracial relationships compared with women in intraracial relationships, but there was no differential impact among men. 相似文献
64.
Development of predictive signatures for treatment selection in precision medicine with survival outcomes 下载免费PDF全文
For survival endpoints in subgroup selection, a score conversion model is often used to convert the set of biomarkers for each patient into a univariate score and using the median of the univariate scores to divide the patients into biomarker‐positive and biomarker‐negative subgroups. However, this may lead to bias in patient subgroup identification regarding the 2 issues: (1) treatment is equally effective for all patients and/or there is no subgroup difference; (2) the median value of the univariate scores as a cutoff may be inappropriate if the sizes of the 2 subgroups are differ substantially. We utilize a univariate composite score method to convert the set of patient's candidate biomarkers to a univariate response score. We propose applying the likelihood ratio test (LRT) to assess homogeneity of the sampled patients to address the first issue. In the context of identification of the subgroup of responders in adaptive design to demonstrate improvement of treatment efficacy (adaptive power), we suggest that subgroup selection is carried out if the LRT is significant. For the second issue, we utilize a likelihood‐based change‐point algorithm to find an optimal cutoff. Our simulation study shows that type I error generally is controlled, while the overall adaptive power to detect treatment effects sacrifices approximately 4.5% for the simulation designs considered by performing the LRT; furthermore, the change‐point algorithm outperforms the median cutoff considerably when the subgroup sizes differ substantially. 相似文献
65.
Response‐adaptive designs for binary responses: How to offer patient benefit while being robust to time trends? 下载免费PDF全文
Response‐adaptive randomisation (RAR) can considerably improve the chances of a successful treatment outcome for patients in a clinical trial by skewing the allocation probability towards better performing treatments as data accumulates. There is considerable interest in using RAR designs in drug development for rare diseases, where traditional designs are not either feasible or ethically questionable. In this paper, we discuss and address a major criticism levelled at RAR: namely, type I error inflation due to an unknown time trend over the course of the trial. The most common cause of this phenomenon is changes in the characteristics of recruited patients—referred to as patient drift. This is a realistic concern for clinical trials in rare diseases due to their lengthly accrual rate. We compute the type I error inflation as a function of the time trend magnitude to determine in which contexts the problem is most exacerbated. We then assess the ability of different correction methods to preserve type I error in these contexts and their performance in terms of other operating characteristics, including patient benefit and power. We make recommendations as to which correction methods are most suitable in the rare disease context for several RAR rules, differentiating between the 2‐armed and the multi‐armed case. We further propose a RAR design for multi‐armed clinical trials, which is computationally efficient and robust to several time trends considered. 相似文献
66.
Chitra Raghavan Connie J. Beck James Michael Menke Jennifer E. Loveland 《Journal of gay & lesbian social services》2019,31(3):370-395
Using mixed methods, we explored the role of coercive controlling behaviors in a high-risk sample of 126 men in violent same-sex relationships. Contrary to a prediction that separate factors of physical violence and coercive control might emerge, a simple principle components analysis supported that male same-sex relationship intimate partner violence (IPV) is essentially unidimensional. Qualitative narratives supported a single latent factor solution of violence, and that coercive controlling behaviors better detect IPV dynamics within the same violent encounters (i.e., weapon use), even when compared to profiles defined by physical violence. Narratives also highlighted gender-different tactics of coercion used, underscoring importance of context-based assessments. 相似文献
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Testing the Effectiveness of Fundraiser Job Titles in Charitable Bequest and Complex Gift Planning 下载免费PDF全文
Russell N. James III 《Nonprofit management & leadership》2016,27(2):165-179
Traditional fundraiser job titles are often institution centered, focusing on the benefits of fundraising as “institutional advancement” or “institutional development.” Such institution‐centered job titles may not be as effective with donors given the modern shift toward donor‐centered philanthropy. Alternative job titles can be gift centered (for example, “major gifts”) or donor centered (for example, “donor advising”). A survey of 3,188 respondents tested sixty‐three job titles in four charitable scenarios: a charitable bequest gift, a gift of stock, a gift of real estate, and a charitable gift annuity. Measured by which person donors would be more likely to contact to discuss each donation, the worst‐performing titles were the traditional institution‐focused fundraiser job titles, in particular those using “advancement,” “institutional advancement,” or “development.” This was also true when examining only respondents who had made large gifts ($500+) to a charity. Traditional institution‐focused job titles are both the most commonly used and the worst performing. Nonprofit managers may do well to consider the donor's perspective when selecting job titles for fundraisers rather than following traditional industry practices. 相似文献
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