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551.
The US National Academy of Sciences (NAS) recently published voluntary guidelines for human embryonic stem (hES) cell research. The NAS guidelines propose two levels of oversight. AT the local level, research institutions are to create Embryonic Stem Cell Research Oversight (ESCRO) committees with a mandate to assess the scientific merit and ethical acceptability of hES cell research. At the national level, a new committee is to be created, not to review specific research proposals, but rather to periodically assess, and as needed revise, the NAS guidelines. In this article, we critically assess this proposal. In particular, we review the benefits and limitations of local research review. On this basis, we argue that local review is insufficient for hES cell research and that while there are obvious pragmatic and political reasons for the NAS to favor local research review, there are more compelling reasons for the NAS to have recommended national review of hES cell research proposals. 相似文献
552.
Liton Chakraborty Jason Thistlethwaite Daniel Scott Daniel Henstra Andrea Minano Horatiu Rus 《Risk analysis》2023,43(5):1058-1078
This study presents the first nationwide spatial assessment of flood risk to identify social vulnerability and flood exposure hotspots that support policies aimed at protecting high-risk populations and geographical regions of Canada. The study used a national-scale flood hazard dataset (pluvial, fluvial, and coastal) to estimate a 1-in-100-year flood exposure of all residential properties across 5721 census tracts. Residential flood exposure data were spatially integrated with a census-based multidimensional social vulnerability index (SoVI) that included demographic, racial/ethnic, and socioeconomic indicators influencing vulnerability. Using Bivariate Local Indicators of Spatial Association (BiLISA) cluster maps, the study identified geographic concentration of flood risk hotspots where high vulnerability coincided with high flood exposure. The results revealed considerable spatial variations in tract-level social vulnerability and flood exposure. Flood risk hotspots belonged to 410 census tracts, 21 census metropolitan areas, and eight provinces comprising about 1.7 million of the total population and 51% of half-a-million residential properties in Canada. Results identify populations and the geographic regions near the core and dense urban areas predominantly occupying those hotspots. Recognizing priority locations is critically important for government interventions and risk mitigation initiatives considering socio-physical aspects of vulnerability to flooding. Findings reinforce a better understanding of geographic flood-disadvantaged neighborhoods across Canada, where interventions are required to target preparedness, response, and recovery resources that foster socially just flood management strategies. 相似文献
553.
Phillips JB 《Omega》2007,55(4):325-346
554.
基于消费者-品牌关系视角的品牌资产研究代表了品牌资产研究的新阶段,但目前还缺乏具有良好理论基础的测量模型和量表。以社会心理学人际关系发展理论为基础,界定基于关系互动的品牌资产概念和维度,建立测量模型;在系统分析已有研究的基础上,结合焦点小组访谈,开展大规模问卷调研,开发基于关系互动的品牌资产测量量表,利用信度分析、探索性因子分析和验证性因子分析方法对量表信度和效度进行检验。研究结果表明,基于关系互动的品牌资产量表具有良好的信度、内容效度、收敛效度和判别效度,该量表包含品牌个性、品牌互惠、品牌礼遇、关系地位和关系能量5个维度。研究结果为后续的实证研究提供了测量基础,同时也为品牌管理者提供了品牌资产评估工具。 相似文献