New Data,Strategies, and Insights for Listeria monocytogenes Dose‐Response Models: Summary of an Interagency Workshop, 2011

Listeria monocytogenes is a leading cause of hospitalization, fetal loss, and death due to foodborne illnesses in the United States. A quantitative assessment of the relative risk of listeriosis associated with the consumption of 23 selected categories of ready‐to‐eat foods, published by the U.S. Department of Health and Human Services and the U.S. Department of Agriculture in 2003, has been instrumental in identifying the food products and practices that pose the greatest listeriosis risk and has guided the evaluation of potential intervention strategies. Dose‐response models, which quantify the relationship between an exposure dose and the probability of adverse health outcomes, were essential components of the risk assessment. However, because of data gaps and limitations in the available data and modeling approaches, considerable uncertainty existed. Since publication of the risk assessment, new data have become available for modeling L. monocytogenes dose‐response. At the same time, recent advances in the understanding of L. monocytogenes pathophysiology and strain diversity have warranted a critical reevaluation of the published dose‐response models. To discuss strategies for modeling L. monocytogenes dose‐response, the Interagency Risk Assessment Consortium (IRAC) and the Joint Institute for Food Safety and Applied Nutrition (JIFSAN) held a scientific workshop in 2011 (details available at http://foodrisk.org/irac/events/ ). The main findings of the workshop and the most current and relevant data identified during the workshop are summarized and presented in the context of L. monocytogenes dose‐response. This article also discusses new insights on dose‐response modeling for L. monocytogenes and research opportunities to meet future needs.     

Sums of powers of binomial coefficients

An asymptotic series for sums of powers of binomial coefficients is derived, the general term being defined and usable with a computer symbolic language. Sums of squares of coefficients in the symmetric case are shown to have a link with classical moment problems, but this property breaks down for cubes and higher powers. Problems of remainders for the asymptotic series are mentioned. Using the reflection formula for I'(.), a continuous form for a binomial function is set up, and this becomes oscillatory outstde the usual range. A new contmued fraction emerges for the logarithm of an adjusted sum of binomial squares. The note is a contribution to the problem of the interpretation of asymptotic series and processes for their convergence acceleration.     

Asymptotocally nonparametric tests with censored paired data

A class of asymptotically nonparametric test with contains a test proposed by Wei(1980), is considered for testing the equality of two continuous distribution funcitons when paired observations are subject to arbitrary right censorship. It is shown that under the null hypothesis each test statistic converges in distribution to the standard normal random variable. Furthermore. the Monte Carlo simulation results indicate that some tests in this class are more powerful than Wei's test. A generalization to incomplete censored paired data is also included.     

Measuring Sharedness of Team-Related Knowledge: Design and Validation of a Shared Mental Model Instrument

Many researchers have explored how people share and construct similar mental models in teams. They have claimed that successful team performance depends on a shared mental model of team members about task, team, equipment and situation. Most of the literature has illustrated simplified relationships between a team's mental model and their performance without a valid instrument addressing the confined and relevant constructs of a shared mental model. This paper describes the instrument development steps and the conceptual framework for factors associated with shared mental models. After development and refinement, the instrument was finalized for use to measure team-related knowledge. The final instrument consists of 42 items that are linked to the five emergent factors of shared mental models including general task and team knowledge, general task and communication skills, attitude toward teammates and task, team dynamics and interactions, and team resources and working environment.     

On second-order improved estimation of a gamma scale parameter

This paper concludes our comprehensive study on point estimation of model parameters of a gamma distribution from a second-order decision theoretic point of view. It should be noted that efficient estimation of gamma model parameters for samples ‘not large’ is a challenging task since the exact sampling distributions of the maximum likelihood estimators and its variants are not known. Estimation of a gamma scale parameter has received less attention from the earlier researchers compared to shape parameter estimation. What we have observed here is that improved estimation of the shape parameter does not necessarily lead to improved scale estimation if a natural moment condition (which is also the maximum likelihood restriction) is satisfied. Therefore, this work deals with the gamma scale parameter estimation as a separate new problem, not as a by-product of the shape parameter estimation, and studies several estimators in terms of second-order risk.