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31.
This paper investigates the relationships of the choice of philanthropic strategy with board capital (diversity and networks), board activities (board processes, internal board committees, and board effectiveness), and CEO leadership. Using a sample of 110 Italian foundations, the research shows that board processes have the strongest positive association with an evolved strategic approach to philanthropic institutional grant-giving, while board diversity and strong CEO leadership are associated with the strategic approach only under certain conditions. In particular, good governance processes (e.g., training the board, self-evaluation of trustees, setting the stage for effective board and committee meetings, implementing control software, and steering meetings to improve the board’s analysis) are positively associated with evolved strategic approaches to philanthropy (e.g., signaling other funders for the best grantees, improving the performance of grant recipients, and advancing selected social fields’ state of knowledge and practice).  相似文献   
32.
Critical infrastructure networks enable social behavior, economic productivity, and the way of life of communities. Disruptions to these cyber–physical–social networks highlight their importance. Recent disruptions caused by natural phenomena, including Hurricanes Harvey and Irma in 2017, have particularly demonstrated the importance of functioning electric power networks. Assessing the economic impact (EI) of electricity outages after a service disruption is a challenging task, particularly when interruption costs vary by the type of electric power use (e.g., residential, commercial, industrial). In contrast with most of the literature, this work proposes an approach to spatially evaluate EIs of disruptions to particular components of the electric power network, thus enabling resilience‐based preparedness planning from economic and community perspectives. Our contribution is a mix‐method approach that combines EI evaluation, component importance analysis, and GIS visualization for decision making. We integrate geographic information systems and an economic evaluation of sporadic electric power outages to provide a tool to assist with prioritizing restoration of power in commercial areas that have the largest impact. By making use of public data describing commercial market value, gross domestic product, and electric area distribution, this article proposes a method to evaluate the EI experienced by commercial districts. A geospatial visualization is presented to observe and compare the areas that are more vulnerable in terms of EI based on the areas covered by each distribution substation. Additionally, a heat map is developed to observe the behavior of disrupted substations to determine the important component exhibiting the highest EI. The proposed resilience analytics approach is applied to analyze outages of substations in the boroughs of New York City.  相似文献   
33.
Many researchers have explored the advantages of modular product design, its design methods and its effects on product performance. Modular design is, for example, required for product platform, mass customization and postponement in order to achieve greater product variety and differentiation. However, a few empirical studies explicitly examine how to coordinate modular product design in a managerial way. This paper addresses it by conducting multiple case studies with six companies which have successfully adopted modular product design for five years. Seven critical factors are explored in the management of modular product design. These are pre-defined product advantage, selectively used design rules, module definition, system integration, technological newness, internal communication, and supplier and customer involvement. While most of the literature studies the technical dimension of modular design within a firm, this study focuses on the managerial side across the supply chain. It gives new insights on how to manage modular product design and proposes future research opportunities.  相似文献   
34.
We address a multi-echelon inventory system with one-warehouse and N  -retailers. The demand at each retailer is assumed to be known and satisfied by the warehouse. Shortages are not allowed and lead times are negligible. Costs at each facility consist of a fixed charge per order and a holding cost. The goal is to determine single-cycle policies which minimize the average cost per unit time, that is, the sum of the average holding and setup costs per unit time at the retailers and at the warehouse. We propose a O(NlogN)O(NlogN) heuristic procedure to compute efficient single-cycle policies. This heuristic is compared with other approaches proposed by Schwarz, Graves and Schwarz and Muckstadt and Roundy. We carry out a computational study to test the effectiveness of the heuristic and to compare the performance of the different procedures. From the computational results, it is shown that the new heuristic provides, on average, better single-cycle policies than those given by the Muckstadt and Roundy method.  相似文献   
35.
Models of Neurotoxicity: Extrapolation of Benchmark Doses in Vitro   总被引:4,自引:0,他引:4  
In risk assessment, no observed exposure level (NOAEL) and benchmark dose (BMD) are usually derived either from epidemiological studies in humans or from animal experiments. In many in vitro studies, concentration-effect/response curves have been analyzed using different mathematical models finalized to the identification of EC50. In the present article, we propose a model to fit dose-response curves in vitro. The BMD approach has been used to compare the cell viability (MIT assay) of different rat (C6 and PC12, glial and neuronal, respectively) and human cell lines (D384 and SK-N-MC, glial and neuronal, respectively) after 24-hour exposure to the following neurotoxic substances: manganese chloride (MnCl2), methyl-mercury (Me-Hg), and the enantiomers of styrene oxide (SO). For all rat and human cell lines, the potency of the examined compounds was: MnCl2 < S-SO < R-SO < Me-Hg. A preliminary comparison with in vivo toxicity data for these substances gave rise to consistent results. Whereas a reasonable agreement between in vitro and in vivo data has been found for Mn and styrene oxide, a wide scatter of LOAEL has been reported for Me-Hg and these appear to be either much higher or lower than the BMD for the MIT assay we observed in vitro.  相似文献   
36.
In this paper we estimate a bargaining model of government formation in parliamentary democracies. We use the estimated structural model to conduct constitutional experiments aimed at evaluating the impact of institutional features of the political environment on the duration of the government formation process, the type of coalitions that form, and their relative stability.  相似文献   
37.
Pet-Armacost  Julia J.  Sepulveda  Jose  Sakude  Milton 《Risk analysis》1999,19(6):1173-1184
The US Department of Transportation was interested in the risks associated with transporting Hydrazine in tanks with and without relief devices. Hydrazine is both highly toxic and flammable, as well as corrosive. Consequently, there was a conflict as to whether a relief device should be used or not. Data were not available on the impact of relief devices on release probabilities or the impact of Hydrazine on the likelihood of fires and explosions. In this paper, a Monte Carlo sensitivity analysis of the unknown parameters was used to assess the risks associated with highway transport of Hydrazine. To help determine whether or not relief devices should be used, fault trees and event trees were used to model the sequences of events that could lead to adverse consequences during transport of Hydrazine. The event probabilities in the event trees were derived as functions of the parameters whose effects were not known. The impacts of these parameters on the risk of toxic exposures, fires, and explosions were analyzed through a Monte Carlo sensitivity analysis and analyzed statistically through an analysis of variance. The analysis allowed the determination of which of the unknown parameters had a significant impact on the risks. It also provided the necessary support to a critical transportation decision even though the values of several key parameters were not known.  相似文献   
38.
Everyday we face all kinds of risks, and insurance is in the business of providing us a means to transfer or share these risks, usually to eliminate or reduce the resulting financial burden, in exchange for a predetermined price or tariff. Actuaries are considered professional experts in the economic assessment of uncertain events, and equipped with many statistical tools for analytics, they help formulate a fair and reasonable tariff associated with these risks. An important part of the process of establishing fair insurance tariffs is risk classification, which involves the grouping of risks into various classes that share a homogeneous set of characteristics allowing the actuary to reasonably price discriminate. This article is a survey paper on the statistical tools for risk classification used in insurance. Because of recent availability of more complex data in the industry together with the technology to analyze these data, we additionally discuss modern techniques that have recently emerged in the statistics discipline and can be used for risk classification. While several of the illustrations discussed in the paper focus on general, or non-life, insurance, several of the principles we examine can be similarly applied to life insurance. Furthermore, we also distinguish between a priori and a posteriori ratemaking. The former is a process which forms the basis for ratemaking when a policyholder is new and insufficient information may be available. The latter process uses additional historical information about policyholder claims when this becomes available. In effect, the resulting a posteriori premium allows one to correct and adjust the previous a priori premium making the price discrimination even more fair and reasonable.  相似文献   
39.
In this paper, we consider three different mixture models based on the Birnbaum-Saunders (BS) distribution, viz., (1) mixture of two different BS distributions, (2) mixture of a BS distribution and a length-biased version of another BS distribution, and (3) mixture of a BS distribution and its length-biased version. For all these models, we study their characteristics including the shape of their density and hazard rate functions. For the maximum likelihood estimation of the model parameters, we use the EM algorithm. For the purpose of illustration, we analyze two data sets related to enzyme and depressive condition problems. In the case of the enzyme data, it is shown that Model 1 provides the best fit, while for the depressive condition data, it is shown all three models fit well with Model 3 providing the best fit.  相似文献   
40.
This paper extends the scedasticity comparison among several groups of observations, usually complying with the homoscedastic and the heteroscedastic cases, in order to deal with data sets laying in an intermediate situation. As is well known, homoscedasticity corresponds to equality in orientation, shape and size of the group scatters. Here our attention is focused on two weaker requirements: scatters with the same orientation, but with different shape and size, or scatters with the same shape and size but different orientation. We introduce a multiple testing procedure that takes into account each of the above conditions. This approach discloses a richer information on the data underlying structure than the classical method only based on homo/heteroscedasticity. At the same time, it allows a more parsimonious parametrization, whenever the patterned model is appropriate to describe the real data. The new inferential methodology is then applied to some well-known data sets, chosen in the multivariate literature, to show the real gain in using this more informative approach. Finally, a wide simulation study illustrates and compares the performance of the proposal using data sets with gradual departure from homoscedasticity.  相似文献   
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