AN ALGORITHM FOR THE CONSTRUCTION OF OPTIMAL OR NEAR-OPTIMAL CHANGE-OVER DESIGNS

This paper presents an algorithm for the construction of optimal or near optimal change-over designs for arbitrary numbers of treatments, periods and units. Previous research on optimality has been either theoretical or has resulted in limited tabulations of small optimal designs. The algorithm consists of a number of steps:first find an optimal direct treatment effects design, ignoring residual effects, and then optimise this class of designs with respect to residual effects. Poor designs are avoided by judicious application of the (M, S)-optimality criterion, and modifications of it, to appropriate matrices. The performance of the algorithm is illustrated by examples.     

Membranes, mitochondria and amoebae: shape models

Most real-world shapes and images are characterized by high variability- they are not rigid, like crystals, for example—but they are strongly structured. Therefore, a fundamental task in the understanding and analysis of such image ensembles is the construction of models that incorporate both variability and structure in a mathematically precise way. The global shape models introduced in Grenander's general pattern theory are intended to do this. In this paper, we describe the representation of two-dimensional mitochondria and membranes in electron microscope photographs, and three-dimensional amoebae in optical sectioning microscopy. There are three kinds of variability to all of these patterns, which these representations accommodate. The first is the variability in shape and viewing orientation. For this, the typical structure is represented via linear, circular and spherical templates, with the variability accomodated via the application of transformations applied to the templates. The transformations form groups: scale, rotation and translation. They are locally applied throughout the continuum and of high dimension. The second is the textural variability; the inside and outside of these basic shapes are subject to random variation, as well as sensor noise. For this, statistical sensor models and Markov random field texture models are used to connect the constituent structures of the shapes to the measured data. The third variability type is associated with the fact that each scene is made up of a variable number of shapes; this number is not assumed to be known a priori. Each scene has a variable number of parameters encoding the transformations of the templates appropriate for that scene. For this, a single posterior distribution is defined over the countable union of spaces representing models of varying numbers of shapes. Bayesian inference is performed via computation of the conditional expectation of the parametrically defined shapes under the posterior. These conditional mean estimates are generated using jump-diffusion processes. Results for membranes, mitochondria and amoebae are shown.     

INTERGENERATIONAL MOBILITY IN THE REPUBLIC OF IRELAND: Does Gender Make a Difference?

This article compares in regression models the effects of occupational status of both fathers and mothers simultaneously upon the attainment of men and women in the Irish Republic. The sample matches male respondents from the 1973/1974 Irish Mobility Study with the labour active female sibling next closest in age. Since the analysis compares working siblings and each 'matched pair' shares the same family origin characteristics, the problems attendant upon using a sample originally of men only are partially avoided. The results advance beyond previous research since, rather than separate models by gender, models include parents and children of both genders, allowing direct rather than indirect evaluation of gender-based determinants of occupational attainment. Both fathers and mothers significantly affect children's attainment, in ways that vary by the child's gender. The results highlight the salience of mothers' attainment for their children and question the 'mainstream' model of equivalent mechanisms of occupational attainment for both genders. Models of social mobility that consider men and women as special instances of a general perspective provide the most fruitful approach for further development.     

ASKING THREATENING QUESTIONS AND SITUATIONAL FRAMING:

Although surveys are extensively used in sociology, there has been a relative neglect of the effect of task definition upon results obtained. The present article examines the effects of one such task variable, length and specificity of the cue, on response sets concerning the frequency and quantity of alcohol consumed. In one survey format, respondents were asked to report the average number of days drinking per month, and the average number of drinks consumed on each of these occasions. In the second format, questions concerning the monthly frequency of alcohol consumption and quantity consumed were decomposed by twelve drinking locations. The results indicate dramatic increases both in terms of frequency and quantity between the two questionnaire formats. Implications of these results are discussed within the framework of the methodological phenomena of telescoping and the social psychological tendency to under-report threatening behaviors.     

On the existence and uniqueness of maximizers of two likelihood functions

While applying theclassical maximum likelihood method for a certain statistical inference problem, Smith and Weissman [5] have noted that there are conditions under which the likelihood function may be unbounded above or may not possess local maximizers. Ariyawansà and Templeton [1] have derived inference procedures for this problem using the theory of structural inference [2,3,4]. Based on numerical experience, and without proof, they state that the resulting likelihood functions possess unique, global maximizers, even in instances where the classical maximum likelihood method fails in the above sense. In this paper, we prove that under quite mild conditions, these likelihood functions that result from the application of the theory of structural inference are well-behaved, and possess unique, global maximizers. This research was supported in part by the Applied Mathematical Sciences subprogram of the U.S. Department of Energy under contract W-31-109-Eng-38 while the author was visiting the Mathematics and Computer Science Division of Argonne National Laboratory, Argonne, Illinois.     

Sampling Strategies for Toxic Air Contaminants

Annual concentrations of toxic air contaminants are of primary concern from the perspective of chronic human exposure assessment and risk analysis. Despite recent advances in air quality monitoring technology, resource and technical constraints often impose limitations on the availability of a sufficient number of ambient concentration measurements for performing environmental risk analysis. Therefore, sample size limitations, representativeness of data, and uncertainties in the estimated annual mean concentration must be examined before performing quantitative risk analysis. In this paper, we discuss several factors that need to be considered in designing field-sampling programs for toxic air contaminants and in verifying compliance with environmental regulations. Specifically, we examine the behavior of SO2, TSP, and CO data as surrogates for toxic air contaminants and as examples of point source, area source, and line source-dominated pollutants, respectively, from the standpoint of sampling design. We demonstrate the use of bootstrap resampling method and normal theory in estimating the annual mean concentration and its 95% confidence bounds from limited sampling data, and illustrate the application of operating characteristic (OC) curves to determine optimum sample size and other sampling strategies. We also outline a statistical procedure, based on a one-sided t-test, that utilizes the sampled concentration data for evaluating whether a sampling site is compliance with relevant ambient guideline concentrations for toxic air contaminants.     

Coaching für Führungskräfte im Krankenhaus Baustein einer Strategie zum Total Quality Management

Coaching of managers in hospitals as component of a total quality management strategy The author delineates the changed conditions of hospitals at the beginning of the new millenium. In order to be up to date with the growing challenges and the need for change a Total Quality Management (TQM) is necessary. This TQM sees the satisfaction of clients and of employees as crucial for all reorganization processes. The realization in everyday hospital life requires a total personnel development concept, with special regard to the managers and their specific needs for support by supervisors resp. coaches.     

African American Women's Self-Concept: Implications for Career Decisions and Career Counseling

The multiple self-referent model (Brown-Collins & Sussewell, 1986) provides a comprehensive framework for understanding the personal, social, and historical aspects of self-concept formation in African American women and has important implications for understanding the complexity of career development issues for Black women. Excerpts from recorded interviews and autobiographical writings of four well-known African American women provide examples of the basic components of this model. Suggested interventions for career counseling with Black female clients are discussed.     

Surname analysis for estimating local concentration of Hispanics and Asians

Surname analysis is a potentially useful technique for identifying members of particular racial, ethnic, or language communities within a population. We review the existing state of the art for identifying persons of Hispanic or Asian origin, based on surnames distinctive of each group. We describe the logic of surname analysis, profile several available surname dictionaries, and illustrate their applications in local redistricting. Results of our ongoing validation studies suggest promising future directions for improving accuracy and broadening applications.This article is based on a paper presented at the annual Population Association of America meetings at Cincinnati, 1 April 1993.