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Recent research on finding appropriate composite endpoints for preclinical Alzheimer's disease has focused considerable effort on finding “optimized” weights in the construction of a weighted composite score. In this paper, several proposed methods are reviewed. Our results indicate no evidence that these methods will increase the power of the test statistics, and some of these weights will introduce biases to the study. Our recommendation is to focus on identifying more sensitive items from clinical practice and appropriate statistical analyses of a large Alzheimer's data set. Once a set of items has been selected, there is no evidence that adding weights will generate more sensitive composite endpoints.  相似文献   
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In this article, the authors examine how temperature and precipitation affect the probability that a retired American between the ages of 65 and 90 walks at least 2.5 hr/wk, using longitudinal data on walking frequency from the Consumption and Activities Mail Survey, a subpanel in the Health and Retirement Survey. Walking behavior is linked with monthly temperature and precipitation data from weather-station reports. The authors found that higher temperatures were associated with a higher probability of walking at least 2.5 hr/wk for women. In contrast, higher temperatures are associated with a lower probability of walking at least 2.5 hr/wk among men. Precipitation is not significantly associated with walking behavior for either gender.  相似文献   
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How school teachers act to challenge racism in schools is a vital concern in an immigrant society like Australia. A 10% response from a self-administered online survey of government (public) primary and secondary school teachers across Sydney, Australia’s largest EthniCity, examines attitudes of classroom teachers towards cultural diversity, goals of multicultural education, and strategies to implement anti-racist strategies. Principal components analysis (PCA) of attitudes tease out the varied influence of opinion on multicultural education, diversity, and anti-racism. Classroom teachers are overwhelmingly supportive of cultural diversity, multicultural education and strategies to combat racism and discrimination, and these views hardly vary across the different geographic zones of the city, unlike attitudes within the general community. However, teacher knowledge about the implementation of multicultural policy does vary, and is positively associated with the extent of population diversity and socio-economic status (SES) of the communities surrounding the schools.  相似文献   
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Abstract

In this article, I explore how neoliberalism dictates the terms of debate about education reform and equity in the U.S. and abroad. In particular, I explain how two paradigmatic reforms – the edTPA evaluation for preservice teachers in the United States and the global initiative Teach For All – have co-opted the discourse of multicultural education in an attempt to advance their own priorities and not those at the heart of the field, thus jeopardising the possibility of real justice. Finally, I envision a way forward, through a theory of revolutionary multicultural education, as we seek to reimagine the terms of debate about the goals of educating all students.  相似文献   
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Few studies have asked children directly about their experiences in out-of-home care. This study uses data collected from 180 nine- to-11-year-old children currently in out-of-home care who were asked about their perceptions and appraisals of out-of-home care. Analysis of variance and chi-square analyses were used to examine whether children's appraisals of their lives following removal from their families of origin differ as a function of age, gender, race/ethnicity, type and severity of maltreatment, length of time in out-of-home care, placement type, attachment to current caregivers, and rating of current caregiver/home. Youth who were sexually and emotionally abused, youth who were satisfied with their current caregivers and placements, and girls were more likely to state that their lives would have been worse had they remained with their families of origin. Youth who were physically abused were more likely to report that their lives would have remained the same. Children living in group care were more likely than those living in family foster care or with kin to report that their lives would have been better had they remained with their families of origin. Differences were not found between children living in family foster care and those living with kin nor did children's appraisals differ based on age, race, ethnicity, length of time in out-of-home care, neglect, or severity of maltreatment.  相似文献   
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The New Public Management (NPM) has often been favorably contrasted with European Public Administration (EPA). This paper attempts to balance this Anglo-American perspective with a relatively new European critique of NPM which its authors call the Neo-Weberian State (NWS). Despite their differences in some key respects, however, it is argued that the NPM and NWS are similar in their sweeping paradigmatic character, their ambiguities and internal inconsistencies, their inability to go beyond instrumental rationality and incorporate forms of hermeneutic and critical reason, and in their advocacy of bureaucracy via participation under certain historical conditions, hence consistent with Weber’s characterization of modern organization and management. The paper, based on the authors’ rendering of critical social theory, provides a fresh means for bridging the two perspectives.
David Y. Miller (Corresponding author)Email:
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