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341.
The aim of this article is to encourage a research agenda that attends to methodological considerations regarding measuring self-perceived racial and ethnic discrimination in social surveys. Toward this end, the author compared validity of alternative measures of discrimination. The first measure asks whether something unfair or bad has happened because of race and ethnicity, whereas the second measure asks about generic unfair events independent of attribution to race or ethnicity. In a probability sample of 586 Black respondents living in the Detroit metropolitan area interviewed in 1995, it was found that the prevalence of self-perceived racial and ethnic discrimination depended on question framing. Moreover, different respondents were likely to respond affirmatively to explicit versus generic measures of discrimination; importantly, the mental health consequences of self-perceived racial and ethnic discrimination varied by question framing. The results confirmed that the prevalence, correlates, and psychological impact of self-perceived discrimination should be evaluated on the basis of measurement sensitivity.  相似文献   
342.
343.
Science on emerging environmental health threats involves numerous ethical concerns related to scientific uncertainty about conducting, interpreting, communicating, and acting upon research findings, but the connections between ethical decision making and scientific uncertainty are under‐studied in sociology. Under conditions of scientific uncertainty, researcher conduct is not fully prescribed by formal ethical codes of conduct, increasing the importance of ethical reflection by researchers, conflicts over research conduct, and reliance on informal ethical standards. This article draws on in‐depth interviews with scientists, regulators, activists, industry representatives, and fire safety experts to explore ethical considerations of moments of uncertainty using a case study of flame retardants, chemicals widely used in consumer products with potential negative health and environmental impacts. We focus on the uncertainty that arises in measuring people's exposure to these chemicals through testing of their personal environments or bodies. We identify four sources of ethical concerns relevant to scientific uncertainty: 1) choosing research questions or methods, 2) interpreting scientific results, 3) communicating results to multiple publics, and 4) applying results for policy making. This research offers lessons about professional conduct under conditions of uncertainty, ethical research practice, democratization of scientific knowledge, and science's impact on policy.  相似文献   
344.
Population-level proportions of individuals that fall at different points in the spectrum [of disease severity], from asymptomatic infection to severe disease, are often difficult to observe, but estimating these quantities can provide information about the nature and severity of the disease in a particular population. Logistic and multinomial regression techniques are often applied to infectious disease modeling of large populations and are suited to identifying variables associated with a particular disease or disease state. However, they are less appropriate for estimating infection state prevalence over time because they do not naturally accommodate known disease dynamics like duration of time an individual is infectious, heterogeneity in the risk of acquiring infection, and patterns of seasonality. We propose a Bayesian compartmental model to estimate latent infection state prevalence over time that easily incorporates known disease dynamics. We demonstrate how and why a stochastic compartmental model is a better approach for determining infection state proportions than multinomial regression is by using a novel method for estimating Bayes factors for models with high-dimensional parameter spaces. We provide an example using visceral leishmaniasis in Brazil and present an empirically-adjusted reproductive number for the infection.  相似文献   
345.
Summary.  We propose an approach for estimating the age at first lower endoscopy examination from current status data that were collected via two series of cross-sectional surveys. To model the national probability of ever having a lower endoscopy examination, we incorporate birth cohort effects into a mixed influence diffusion model. We link a state-specific model to the national level diffusion model by using a marginalized modelling approach. In future research, results from our model will be used as microsimulation model inputs to estimate the contribution of endoscopy examinations to observed changes in colorectal cancer incidence and mortality.  相似文献   
346.
The asymptotic structure of a vector of weighted sums of signs of residuals, in the general linear model, is studied. The vector can be used as a basis for outlier-detection tests, or alternatively, setting the vector to zero and solving for the parameter yields a class of robust estimators which are analogues of the sample median. Asymptotic results for both estimates and tests are obtained. The question of optimal weights is investigated, and the optimal estimators in the case of simple linear regression are found to coincide with estimators introduced by Adichie.  相似文献   
347.
Much of the literature on mothering a child with a disability focuses on grief in the context of diagnosis, with a paucity of longitudinal studies focusing on ongoing grief as the child moves through the life stages. This qualitative study explores the existence of recurrent grief within the lived experience of six women, in mothering their children with intellectual disability through to young adulthood. Informed by the differing theories of grief and disability, the study considers mothers' perception of the experience of recurrent grief as influenced by personal and societal factors, with a focus on its triggers, its manifestation and its amelioration. The findings have relevance to social work practice, policy and research in revealing the necessity for ongoing support and advocacy for mothers of children and young adults with intellectual disabilities.  相似文献   
348.
Zonies K 《Physician executive》2008,34(1):18-20, 22
Learn why a renewal of primary care could help save the U.S. healthcare system. Take a look at seven suggestions tosave primary care.  相似文献   
349.
常有人向我咨询合伙事宜。同事或朋友邀请他们参与某个合作项目,他们认为那是“千载难逢的好机会”。而这些机会不是需要投入大量的钱和时间,就是涉及与当前职业完全不同的新领域,有时甚至是两种情况兼具。  相似文献   
350.
This paper provides evidence of links between the nature of strategic formulation within firms and subsequent plant performance. The research focuses on how some firms have managed to link operations and supply into an integrated set of mutually supportive strategies. In the current competitive arena firms can no longer rely wholly on internal resource-based capabilities but must instead form strategic partnerships within what are often complex networks. The paper explores how operations and supply functions have pursued parallel paths but have often not been fully integrated within firms. It is argued that such integration, which forms part of what has been termed strategic resonance , can reap enormous benefits in terms of plant-level capabilities for firms.  相似文献   
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