Street children and crime in the UK: a case of abuse and neglect

It is claimed that many incidences of children running away from home and residential care involve issues around violence, bullying and child abuse and neglect. Surveys show that between 14 and 20% of children run away from home for at least one night and that 2% run away 10 times or more from home or a care setting. The potential reasons for running away are discussed together with the increased possibility for further victimization, delinquency and criminal behaviour. Four ‘streetwork projects’ that provide information and support to young runaways in the UK are described and their limitations discussed. It is proposed that counselling should be a part of intervention with street children and that trained counsellors/psychotherapists should be available free to these young people with social and emotional difficulties outside the usual health/social service provision. © 1998 John Wiley & Sons, Ltd.     

Adolescents' attention to traditional and graphic tobacco warning labels: an eye-tracking approach

The objective of this study was determine if the inclusion of Canadian-style graphic images would improve the degree to which adolescents attend to, and subsequently are able to recall, novel warning messages in tobacco magazine advertising. Specifically, our goal was to determine if the inclusion of graphic images would (1) increase visual attention, as measured by eye movement patterns and fixation density, and (2) improve memory for tobacco advertisements among a group of 12 to 14 year olds in the western United States. Data were collected from 32 middle school students using a head-mounted eye-tracking device that recorded viewing time, scan path patterns, fixation locations, and dwell time. Participants viewed a series of 20 magazine advertisements that included five U.S. tobacco ads with traditional Surgeon General warning messages and five U.S. tobacco ads that had been modified to include non-traditional messages and Canadian-style graphic images. Following eye tracking, participants completed unaided- and aided-recall exercises. Overall, the participants spent equal amounts of time viewing the advertisements regardless of the type of warning message. However, the warning messages that included the graphic images generated higher levels of visual attention directed specifically toward the message, based on average dwell time and fixation frequency, and were more likely to be accurately recalled than the traditional warning messages.     

Migration Processes,Familial Characteristics,and Schooling Dropout Among Black Youths

This study uses data from the 2000 U.S. census to examine whether the schooling advantage of black immigrants’ children found in previous studies is robust. According to the results, the advantage associated with having migrant parents is not restricted to the children of immigrants. Black migrant parents, regardless of foreign-born status, have children with favorable schooling outcomes. Such parental-level influences, however, seem stronger among some immigrant groups than among native internal migrants. The study also suggests that the collective advantage of the children of immigrants is driven by positive migrant selectivity. Accordingly, comparisons between the children of native migrants and children in various immigrant groups reveal that the immigrant advantage is not robust. In fact, the results suggest that when immigrant ethnicity is considered, some children of immigrants may be disadvantaged relative to the children of native migrants. Among recent migrants, the children of native internal migrants also have more favorable outcomes than the children of immigrants, although these differences disappear after background factors are controlled. Further, internal-migrant and immigrant households are less likely to have characteristics that adversely affect schooling than nonmigrant households. Unsurprisingly, the children of nonmigrants have the worst outcomes among black youths.     

Migration, Household Configurations, and the Well-Being of Adolescent Orphans in Rwanda

This study uses data from the 2002 Rwandan census to situate the discourse on migration and orphan well-being within the context of the household. According to its findings, migrant orphans are less likely than non-migrant orphans to live in households with less favorable structural characteristics such as single-parent households. Significant differences are also found in the implied gains to living standards and schooling associated with migration among paternal, maternal, and double-orphans. However, the higher living standards and schooling attainment of orphan migrants relative to their non-migrant counterparts disappear within child-headed household contexts. More generally, the results indicate that the higher living standards of migrant orphans are in part driven by the fact that they mostly live in households with migrant household-heads or migrant spouses. Yet the analysis also suggests that orphans living within these contexts experience higher levels of intra-household discrimination in investments in their schooling, relative to their orphan counterparts who live in non-migrant households.     

A case study in identifying targeted patients population in major depressive disorder by enhanced enrichment design

Despite advances in clinical trial design, failure rates near 80% in phase 2 and 50% in phase 3 have recently been reported. The challenges to successful drug development are particularly acute in central nervous system trials such as for pain, schizophrenia, mania, and depression because high‐placebo response rates lessen assay sensitivity, diminish estimated treatment effect sizes, and thereby decrease statistical power. This paper addresses the importance of rigorous patient selection in major depressive disorder trials through an enhanced enrichment paradigm. This approach led to a redefinition of an ongoing, blinded phase 3 trial algorithm for patient inclusion (1) to eliminate further randomization of transient placebo responders and (2) to exclude previously randomized transient responders from the primary analysis of the double blind phase of the trial. It is illustrated for a case study for the comparison between brexpiprazole + antidepressant therapy and placebo + antidepressant therapy. Analysis of the primary endpoint showed that efficacy of brexpiprazole versus placebo could not be established statistically if the original algorithm for identification of placebo responders was used, but the enhanced enrichment approach did statistically demonstrate efficacy. Additionally, the enhanced enrichment approach identified a target population with a clinically meaningful treatment effect. Through its successful identification of a target population, the innovative enhanced enrichment approach enabled the demonstration of a positive treatment effect in a very challenging area of depression research.     

Supervisory procedural justice effects: The mediating roles of cognitive and affective trust

We tested a model in which two bases of trust mediated the effects of supervisory procedural justice. Two conceptually distinct mechanisms were proposed to explain how different procedural justice effects are manifested. Structural equation modeling results using 203 individuals with matched supervisory ratings from a cross-section of organizations located in Taiwan supported our model. Cognitive trust mediated the relations of supervisory procedural justice with performance and job satisfaction, whereas affective trust mediated relations between supervisory procedural justice and helping behavior at work.     

Effects of Aerobic Training on Primary Dysmenorrhea Symptomatology in College Females

Abstract

“Single-Dose Therapy for Cystitis in Women: A Comparison of Trimethoprim-Sulfamethoxazole, Amoxicillin, and Cyclacillin,” Thomas M. Hooton et al. We evaluated single-dose regimens of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin as treatment for acute cystitis in 38 women. The trial was prematurely stopped because of frequent treatment failures. At two days after treatment, all 13 patients given trimethoprim-sulfamethoxazole were cured, while four (31%) of the 13 given amoxicillin and four (33%) of 12 given cyclacillin had persistent bacteriuria. At two weeks, 11 (85%) of 13 patients given trimethoprim-sulfamethoxazole, six (50%) of 12 given amoxicillin, and three (30%) of ten given cyclacillin were cured. One patient with positive results of antibody-coated bacteria testing who was treated with cyclacillin had signs and symptoms of acute pyelonephritis three days after treatment, and two patients treated with amoxicillin and one treated with trimethoprim-sulfamethoxazole converted antibody-coated bacteria test results from negative to positive after therapy. We conclude that single-dose treatment of cystitis in unselected women with cyclacillin and amoxicillin may result in low cure rates and that progression to acute pyelonephritis may occur following ineffective single-dose therapy. (Journal of the American Medical Association 1985;253:387-390.)