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91.
92.
Combining Food Frequency and Survey Data to Quantify Long-Term Dietary Exposure: A Methyl Mercury Case Study 总被引:2,自引:0,他引:2
Twenty-four-hour recall data from the Continuing Survey of Food Intake by Individuals (CSFII) are frequently used to estimate dietary exposure for risk assessment. Food frequency questionnaires are traditional instruments of epidemiological research; however, their application in dietary exposure and risk assessment has been limited. This article presents a probabilistic method of bridging the National Health and Nutrition Examination Survey (NHANES) food frequency and the CSFII data to estimate longitudinal (usual) intake, using a case study of seafood mercury exposures for two population subgroups (females 16 to 49 years and children 1 to 5 years). Two hundred forty-nine CSFII food codes were mapped into 28 NHANES fish/shellfish categories. FDA and state/local seafood mercury data were used. A uniform distribution with minimum and maximum blood-diet ratios of 0.66 to 1.07 was assumed. A probabilistic assessment was conducted to estimate distributions of individual 30-day average daily fish/shellfish intakes, methyl mercury exposure, and blood levels. The upper percentile estimates of fish and shellfish intakes based on the 30-day daily averages were lower than those based on two- and three-day daily averages. These results support previous findings that distributions of "usual" intakes based on a small number of consumption days provide overestimates in the upper percentiles. About 10% of the females (16 to 49 years) and children (1 to 5 years) may be exposed to mercury levels above the EPA's RfD. The predicted 75th and 90th percentile blood mercury levels for the females in the 16-to-49-year group were similar to those reported by NHANES. The predicted 90th percentile blood mercury levels for children in the 1-to-5-year subgroup was similar to NHANES and the 75th percentile estimates were slightly above the NHANES. 相似文献
93.
Eonsoo Kim Author Vitae 《Journal of Management》2004,30(5):569-589
Because current management theories evolved in the context of brick-and-mortar firms, this paper examines three key questions raised by the advent of e-business: (1) Will the strategy types found among e-business firms resemble Porter’s (1980) generic strategies? (2) Will we find performance differences among e-business firms pursuing different types of strategies? (3) Will we find differences in the strategy-performance relationships of pure online firms (pure plays) and firms with both online and offline operations (clicks-and-bricks)? We conclude that integrated strategies that combine elements of cost leadership and differentiation will outperform cost leadership or differentiation strategies. We also argue that, regardless of business strategy type, clicks-and-bricks firms that closely integrate their on- and offline operations will enjoy performance advantages over their pure play counterparts. 相似文献
94.
This paper draws together evidence from across the UK public services to present an analysis of public sector organisational change that has been observed and experienced since the 1980s. The argument is that the pattern of persistent change, packaged as a myriad of reform measures, has been centrally concerned with solving the labour problem—low worker productivity and managers not being able to manage—in what are labour intensive services. The now familiar managerial discourse of empowerment and high commitment working practices is highlighted and express linkages are drawn between such themes and the day-to-day practices of performance and human resource management, seen here to be key levers in solving the same labour problem through a reduction in the quality of working lives of many public service workers. 相似文献
95.
Dipl.-Kffr. Ju-Young Kim Prof. Dr. Martin Natter Prof. Dr. Martin Spann 《Zeitschrift für Betriebswirtschaft》2010,80(2):147-169
Pay-What-You-Want (PWYW) is a participative pricing mechanism which is characterized by the fact that consumers have maximum control over the price they pay. We discuss the business relevance of PWYW and extend the findings of Kim et al. (2009) using latent class regression. Two different classes can be identified and transaction prices are explained by psycho- and socio-demographics. The estimation of the parameters shows that the internal reference price is a good predictor for the prices in class 1, whereas in the 2nd class the level of fairness and satisfaction with the product positively affect the final transaction prices. 相似文献
96.
In this paper, we consider the fire scheduling problem (FSP) for field artillery, which is the problem of scheduling operations of firing at given targets with a given set of weapons. We consider a situation in which the number of available weapons is smaller than the number of targets, the targets are assigned to the weapons already, and targets may move and hence the probability that a target is destroyed by a firing attack decreases as time passes. We present a branch and bound algorithm for the FSP with the objective of minimizing total threat of the targets, which is expressed as a function of the destruction probabilities of the targets. Results of computational tests show that the suggested algorithm solves problems of a medium size in a reasonable amount of computation time. 相似文献
97.
Lack of a valid instrument to measure learning transfer predictors has been the major obstacle hindering Human Resource Development (HRD) professionals from moving forward. This problem is one of the lingering HRD issues in South Korea, in which human resources have been strategically emphasized as a critical asset due to the scarcity of natural resources. To address this issue, this study aims at testing the validity and reliability of the data collected with the Korean Learning Transfer System Inventory (LTSI) Version 4. A sample of 753 managers from 16 Korean industries was divided into two subsamples for exploratory and confirmatory factor analyses. Reliability and the effect of common method variance on the factor structure were examined, with the results suggesting that the LTSI is valid for use in the Korean industry. 相似文献
98.
This analysis of International Business (IB) corruption literature identifies gaps and inconsistencies in how corruption is perceived or deliberated in top academic journals. The reviewed articles tend to focus on one of the three key themes of IB corruption (Contributing factors, Consequences, and Combating) and are categorised into the six sub-domains of the IB framework. The content of the articles is categorised into the respective themes and discussed in relation to underpinning theories and key constructs. The process is intended to be less a synthesis of the literature than an audit revealing that IB corruption research is weakened by tendencies to: 1) Be siloed within its subtheme and to not cross-tie to work in other key themes—this issue is very severe in the Combating theme; 2) Have a short-term focus that disregards the cumulative effects of total graft, and; 3) Asymmetrically focus (predominantly) on the supply side of corruption. These finding suggest several avenues for further research. 相似文献
99.
This study identifies the determinants of appointment of executives in quangos. Using data from 85 quangos in Korea over 15 years between 1993 and 2007, we investigate the degree to which various characteristics of organizational actors affect the choice of executives. Three organizational actors include presidents, sponsoring government departments, and the concerned quangos. Although results vary by executive position, the findings of the empirical analysis with multinomial probit and generalized linear mixed models support the idea that the appointment of quango executives is not the result of presidential choice but that of the interactions among the key organizational actors, with different incentives and resources, on the appointment. Compared to former bureaucrats, presidential allies are more likely to be appointed when presidents have more political support from the National Assembly and it is easier for insiders to be promoted as executives from larger and older quangos with clear legal origins. 相似文献
100.
The Value of Information in Decision‐Analytic Modeling for Malaria Vector Control in East Africa 下载免费PDF全文
Dohyeong Kim Zachary Brown Richard Anderson Clifford Mutero Marie Lynn Miranda Jonathan Wiener Randall Kramer 《Risk analysis》2017,37(2):231-244
Decision analysis tools and mathematical modeling are increasingly emphasized in malaria control programs worldwide to improve resource allocation and address ongoing challenges with sustainability. However, such tools require substantial scientific evidence, which is costly to acquire. The value of information (VOI) has been proposed as a metric for gauging the value of reduced model uncertainty. We apply this concept to an evidenced‐based Malaria Decision Analysis Support Tool (MDAST) designed for application in East Africa. In developing MDAST, substantial gaps in the scientific evidence base were identified regarding insecticide resistance in malaria vector control and the effectiveness of alternative mosquito control approaches, including larviciding. We identify four entomological parameters in the model (two for insecticide resistance and two for larviciding) that involve high levels of uncertainty and to which outputs in MDAST are sensitive. We estimate and compare a VOI for combinations of these parameters in evaluating three policy alternatives relative to a status quo policy. We find having perfect information on the uncertain parameters could improve program net benefits by up to 5–21%, with the highest VOI associated with jointly eliminating uncertainty about reproductive speed of malaria‐transmitting mosquitoes and initial efficacy of larviciding at reducing the emergence of new adult mosquitoes. Future research on parameter uncertainty in decision analysis of malaria control policy should investigate the VOI with respect to other aspects of malaria transmission (such as antimalarial resistance), the costs of reducing uncertainty in these parameters, and the extent to which imperfect information about these parameters can improve payoffs. 相似文献