First Nations and community economic development: a case study

A training project in a northern Canadian community providedan opportunity to examine participatory planning approachesand the meaning of work in First Nations communities. Focusgroups conducted three years after the unsuccessful interventionof a community economic development (CED) project suggest thatcomplex factors such as lack of support from community leadersand rate of pay for workers determine whether CED is alwaysappropriate in northern, First Nations contexts.     

Who Gets What From Government? Distributional Consequences of Child‐Care Assistance Policies

Given the fragmented structure of child‐care assistance in the United States, it has been difficult to obtain accurate estimates of which families are assisted, through which mechanisms, and at what level. Making use of survey data from New York City, we analyze the distribution of several forms of public child‐care assistance. Results suggest that about 40% of all families with young children receive some form of child‐care assistance. Considering all forms of assistance, the distribution of child‐care help is targeted in both expected and some unexpected ways. Implications of these results are discussed in the context of U.S. child‐care policies governing access and benefit levels.     

The role of family help in the housing decisions of young people

Recent debates about flows of help within the family have indicated considerable diversity according to the type of help (money, services), and ages and gender of those involved, and have shown that values are only a partial guide to the scale of such flows. This paper focuses on a particular occasion for help, young people's housing, and a particular region, South-East England, where one would expect family financial help to be high given the capacity to help of older generations (due to higher average incomes and wealth) and the affordability problems faced by young people. It is shown that contrary to hypothesis only 12% of a sample of young people had received financial help for housing purposes since they had left home, less than found in previous studies with different samples. The amounts involved were less than young people believed their parents could afford. The role of inheritance was also found to be minor. The results from the different studies are explained as due to changes in the housing market, changing values regarding financial help and differences among the samples. Intensive re-interviews with three households from very different backgrounds are used to show the different ways in which family help operates.     

亚当·斯密的公路经济理论

研究了亚当.斯密公路经济理论的几个重要观点:公路的选址和规模、资金筹措、运营和征收车辆通行税等,并分析了车辆通行税管理权划归中央或地方的标准,得出建立监督机制、关注乡村公路和偏远公路有利于公路发展的结论,这对中国公路建设理论与实践有重要的借鉴作用。     

Defining the linear portion of a sigmoid‐shaped curve: bend points

Formulae are provided that define the ‘bend points’, the beginning and end of the essentially linear dose–response region, for the four‐parameter logistic model. The formulae are expressed in both response and dose units. The derivation of the formulae is shown in order to illustrate the general nature of the methodology. Examples are given that describe how the formulae may be used while planning and conducting bioassays. Copyright © 2003 John Wiley & Sons, Ltd.     

Exposure Reconstruction for the TCDD-Exposed NIOSH Cohort Using a Concentration- and Age-Dependent Model of Elimination

Recent studies demonstrating a concentration dependence of elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suggest that previous estimates of exposure for occupationally exposed cohorts may have underestimated actual exposure, resulting in a potential overestimate of the carcinogenic potency of TCDD in humans based on the mortality data for these cohorts. Using a database on U.S. chemical manufacturing workers potentially exposed to TCDD compiled by the National Institute for Occupational Safety and Health (NIOSH), we evaluated the impact of using a concentration- and age-dependent elimination model (CADM) (Aylward et al., 2005) on estimates of serum lipid area under the curve (AUC) for the NIOSH cohort. These data were used previously by Steenland et al. (2001) in combination with a first-order elimination model with an 8.7-year half-life to estimate cumulative serum lipid concentration (equivalent to AUC) for these workers for use in cancer dose-response assessment. Serum lipid TCDD measurements taken in 1988 for a subset of the cohort were combined with the NIOSH job exposure matrix and work histories to estimate dose rates per unit of exposure score. We evaluated the effect of choices in regression model (regression on untransformed vs. ln-transformed data and inclusion of a nonzero regression intercept) as well as the impact of choices of elimination models and parameters on estimated AUCs for the cohort. Central estimates for dose rate parameters derived from the serum-sampled subcohort were applied with the elimination models to time-specific exposure scores for the entire cohort to generate AUC estimates for all cohort members. Use of the CADM resulted in improved model fits to the serum sampling data compared to the first-order models. Dose rates varied by a factor of 50 among different combinations of elimination model, parameter sets, and regression models. Use of a CADM results in increases of up to five-fold in AUC estimates for the more highly exposed members of the cohort compared to estimates obtained using the first-order model with 8.7-year half-life. This degree of variation in the AUC estimates for this cohort would affect substantially the cancer potency estimates derived from the mortality data from this cohort. Such variability and uncertainty in the reconstructed serum lipid AUC estimates for this cohort, depending on elimination model, parameter set, and regression model, have not been described previously and are critical components in evaluating the dose-response data from the occupationally exposed populations.     

追求新亚洲安全:文化视角中的地区合作

21世纪各个国家特别是亚洲各国进入了发展的新阶段。亚洲在经济发展中实现了建设性的双边伙伴关系。但是亚洲国家形成“与西方传统不同的亚洲国际关系模式”仍然任重道远。作者认为,亚洲共同的文化认同可以发挥重要作用,理应把亚洲国家特别是两个人口最多的国家中国和印度团结起来,全面实现“亚洲共同体”的战略目标。