Obtaining a Trapezoidal Distribution

Given a most believed value for a quantity together with upper and lower possible deviations from that value, a rectangular distribution might be used to represent state-of-knowledge about the quantity. If the deviations are themselves known by probability distributions, and the value conditioned on the deviations is rectangular, then the marginal distribution of the value is determined by the distributions of the deviations. Here we show under quite general conditions that conversely, given the marginal distribution, the distributions of the deviations are uniquely determined. The case in which the marginal distribution is trapezoidal is studied in some detail.     

Age-period-cohort analysis: an illustration of the problems in assessing interaction in one observation per cell data

This paper discusses the specific problems of age-period-cohort (A-P-C) analysis within the general framework of interaction assessment for two-way cross-classified data with one observation per cell. The A-P-C multiple classification model containing the effects of age groups (rows), periods of observation (columns), and birth cohorts (diagonals of the two-way table) is characterized as one of a special class of models involving interaction terms assumed to have very specific forms. The so-called A-P-C identification problem, which results from the use of a particular interaction structure for detecting cohort effects, is shown to manifest itself in the form of an exact linear dependency among the columns of the design matrix. The precise relationship holding among these columns is derived, as is an explicit formula for the bias in the parameter estimates resulting from an incorrect specification of an assumed restriction on the parameters required to solve the normal equations. Current methods for modeling A-P-C data are critically reviewed, an illustrative numerical example is presented, and one potentially promising analysis strategy is discussed. However, gien the large number of possible sources for error in A-P-C analyses, it is strongly recommended that the results of such analyses be interpreted with a great deal of caution.     

Umvu estimators for the population mean and variance based on random effects models for lognormal data

Cross-classified data are often obtained in controlled experimental situations and in epidemiologic studies. As an example of the latter, occupational health studies sometimes require personal exposure measurements on a random sample of workers from one or more job groups, in one or more plant locations, on several different sampling dates. Because the marginal distributions of exposure data from such studies are generally right-skewed and well-approximated as lognormal, researchers in this area often consider the use of ANOVA models after a logarithmic transformation. While it is then of interest to estimate original-scale population parameters (e.g., the overall mean and variance), standard candidates such as maximum likelihood estimators (MLEs) can be unstable and highly biased. Uniformly minimum variance unbiased (UMVU) cstiniators offer a viable alternative, and are adaptable to sampling schemes that are typiral of experimental or epidemiologic studies. In this paper, we provide UMVU estimators for the mean and variance under two random effects ANOVA models for logtransformed data. We illustrate substantial mean squared error gains relative to the MLE when estimating the mean under a one-way classification. We illustrate that the results can readily be extended to encompass a useful class of purely random effects models, provided that the study data are balanced.     

The robustness of the likelihood ratio test,the nonparametric sum rank test,and f-ratio tests when the populations are from the negative binomial family

In this study, the robustness of power and significance level of several statistical testing methods was evaluated under the assumption that the test populations were from Poisson, negative binomial, or geometric distributions. The F-ratio test, with or without appropriate transformations, was shown to be both safe and robust for all distributions examined.     

Issues in blinded sample size re-estimation

The utility of blinded sample size re-estimation for clinical trials depends on the ability to estimate variability without providing information about the true treatment difference, and on some reasonable assurance that the method is not likely to cause the sample size to be increased when the treatment effect is better than anticipated. We show that violations of these properties are unlikely to occur in practice.     

360 Video: A prototyping process for developing virtual reality interventions

Abstract

Virtual reality (VR) has emerged as a promising technological intervention for anxiety disorders. However, there are no existing standards and best practices to evaluate the effectiveness of environments to achieve their intervention goals. The purpose of this study was to develop a VR intervention for student veterans with social anxiety disorder and test feasibility utilizing a three-stage development model. The development of a therapeutic VR environment may benefit from an interdisciplinary collaboration of researchers from various fields of study. Utilizing three stages of prototyping with two virtual reality platforms, fully immersive video (n?=?6) and three-dimensional (3-D) immersive virtual reality (n?=?8), the research team designed an intervention for student veterans with social anxiety disorder, testing bio-reactivity of participants. Results of prototyping include user feedback validating increased stress levels and increased bio-reactivity specifically in galvanic skin response and heart rate elevation. Implications include the use of 360° video for prototyping 3-D virtual reality interventions.     

Experimental Coastal Land Reclamation: Qianhai as a Case Interpreted

ABSTRACT

Informed by a Coasian transaction cost paradigm enriched by the concept of Schumpeterian innovations, this paper discusses the advantages of using experimental coastal reclamation of the sea to build new cities with a policy for fostering innovations. A new development area at the margin of Shenzhen in China, Qianhai, is used to demonstrate how urban expansion by urban sprawling in a megacity can be avoided by reclamation of marginal land as analytically less costly than along intra-marginal land and more suitable for experimentation for the type of megacity concept that Qianhai aims to achieve.