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101.
Data from the 1979 National Longitudinal Survey of Youth were employed to explore the association between boomerang fathering from birth to age 18 on adolescent depressive symptomatology (N = 3,731). We examined the effects of experiencing a biological father exiting and entering the home because of breaking up and repartnering with an adolescent's mother (i.e., “boomerang fathering”) when compared with other father residential patterns on adolescent depression. Findings suggest that boomerang fathering is more beneficial than harmful. Adolescent females exposed to boomerang fathering, as well as those exposed to fathers who resided with them from birth to age 18, reported significantly lower depressive symptoms when compared with females exposed to fathers who exited the household and never returned. Boomerang fathering was not significantly associated with male adolescent depressive symptomatology. Providing greater family support during times of instability may assist in unifying families and be an indirect source of mental health prevention. 相似文献
102.
Ruth Ogden Halstead Thomas W. Pavkov Lorna L. Hecker Michelle M. Seliner 《Journal of marital and family therapy》2014,40(2):246-259
This study tested the relationship between family dynamics and self‐injury. A total of 189 participants responded to a web‐based survey collecting information related to previous self‐injury behaviors and family dynamics. Participants were over 18 years old who had used self‐injury (intentionally harming themselves physically to relieve painful emotions without suicidal intent), but who had not used self‐injury for over a year. Results indicated that healthy family dynamics were negatively correlated and associated with higher scores of self‐injury behaviors. This study offers some evidence that family dynamics influence self‐injury behaviors. The implications for family therapy are discussed. 相似文献
103.
Traditional medical training may actually impede a physician's ability to solve complex problems because it is based on vertical, linear and traditional thinking. 相似文献
104.
The increasing acknowledgement of the importance of urban habitats in the maintenance of biodiversity has brought with it a need to quantify this importance at a scale appropriate to the characteristic patch sizes encountered in urban areas. Taking a study area in the Black Country (UK) we used a spatially complete, rapid assessment method to evaluate habitat patches in terms of their internal structural heterogeneity. This method recognises the importance of both natural and anthropogenic processes in providing a diverse range of habitats and niches for both flora and fauna. It also recognises the key role of context in determining the ecological significance of each patch within the urban landscape.All habitats studied had a complex mix of both natural and artificial structural elements, where an element is a within-patch contributor to structural diversity, with each habitat type having a large range of element totals. Characteristic totals, reflecting the level of habitat structural diversity, were observed in some habitat types with residential areas having high values and industrial and commercial areas having low values. Certain structural elements were also associated with each habitat type allowing characteristic element assemblages to be derived. If structural diversity is linked with biodiversity, as seems to be the case in many (though not all) habitat types, then this unique method of viewing the urban landscape becomes a powerful tool for informing wildlife ecologists, nature conservationists, urban planners, environmental managers and landscape architects. 相似文献
105.
In 2008, the PSI Toxicology Special Interest Group met to discuss the design and analysis of dog telemetry studies. The dog telemetry study is one component of the integrated cardiovascular assessment required by regulatory bodies. Although there are guidelines for these studies, little is said about the statistical analysis. With parameters of interest measured continually over time, in studies typically involving four dogs, the analysis is not straightforward. This has led to many different types of analysis being proposed in the literature, with many different methods applied within the pharmaceutical industry itself. This paper summarizes the PSI Toxicology group's discussions and recommendations around these issues. 相似文献
106.
Jenkins M Flynn A Smart T Harbron C Sabin T Ratnayake J Delmar P Herath A Jarvis P Matcham J;PSI Biomarker Special Interest Group 《Pharmaceutical statistics》2011,10(6):494-507
Biomarkers play an increasingly important role in many aspects of pharmaceutical discovery and development, including personalized medicine and the assessment of safety data, with heavy reliance being placed on their delivery. Statisticians have a fundamental role to play in ensuring that biomarkers and the data they generate are used appropriately and to address relevant objectives such as the estimation of biological effects or the forecast of outcomes so that claims of predictivity or surrogacy are only made based upon sound scientific arguments. This includes ensuring that studies are designed to answer specific and pertinent questions, that the analyses performed account for all levels and sources of variability and that the conclusions drawn are robust in the presence of multiplicity and confounding factors, especially as many biomarkers are multidimensional or may be an indirect measure of the clinical outcome. In all of these areas, as in any area of drug development, statistical best practice incorporating both scientific rigor and a practical understanding of the situation should be followed. This article is intended as an introduction for statisticians embarking upon biomarker-based work and discusses these issues from a practising statistician's perspective with reference to examples. 相似文献
107.
The Statisticians in the Pharmaceutical Industry Toxicology Special Interest Group has collated and compared statistical analysis methods for a number of toxicology study types including general toxicology, genetic toxicology, safety pharmacology and carcinogenicity. In this paper, we present the study design, experimental units and analysis methods. 相似文献
108.
ABSTRACTVery little is known about how people perceive and respond to sexual relationships between students and teachers, and even less is known about how adolescents view these relationships. In this study, a large sample of high school students (N = 1203; Mean age: 16.83) responded to four scenarios describing a sexual relationship between a student and teacher. We manipulated student and teacher age, and the power differential between the student and teacher and we measured perceptions of wrongness and likelihood of reporting the situation. The data indicated that in situations of older students (18 vs. 14 or 16) and younger teachers (21 vs 30 or 40), they are less likely to be perceived as wrong and less likely to be reported. Likewise, situations were judged as more wrong when the power differential between students and teachers was greater. Further, there were strong gender differences, such that females (vs. males) consistently viewed the situations as more wrong and were more likely to report. Implications for future research and policy are discussed. 相似文献
109.
110.
Erika Hernandez Katie Carmichael ükran Kili Julie C. Dunsmore 《Social Development》2019,28(4):761-781
The concept of linguistic indirectness is well established within the field of pragmatics, in which it has been observed that speakers express ideas directly and indirectly. We integrated the analysis of linguistic directness and indirectness with the examination of two established measures of parental emotion socialization through reminiscing: elaboration and emotion explanations. We examined the unique associations of parents’ direct and indirect elaboration and emotion explanations with preschoolers’ emotion regulation and psychosocial adjustment. Participants were 55 parent–preschooler dyads (31 girls, 24 boys). The dyads reminisced about positive and negative events. Conversations were coded for parental elaboration, parental use of emotion explanations, and parental linguistic directness and indirectness. Children's emotion regulation was observed during standard tasks, and teachers reported on children's psychosocial adjustment. Multivariate regressions including direct elaboration and direct emotion explanations indicated that parents who engaged in more indirect elaboration when discussing positive events had children with worse emotion regulation. Parents who used indirect emotion explanations when discussing positive events had children with better psychosocial adjustment. Parents’ indirect speech during negative event discussions was not related to child outcomes. The results suggest differential functions for indirect elaboration and indirect emotion explanations in relation to children's social outcomes, and support the utility of examining linguistic indirectness. 相似文献