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91.
We consider the problem of estimating the two parameters of the discrete Good distribution. We first show that the sufficient statistics for the parameters are the arithmetic and the geometric means. The maximum likelihood estimators (MLE's) of the parameters are obtained by solving numerically a system of equations involving the Lerch zeta function and the sufficient statistics. We find an expression for the asymptotic variance-covariance matrix of the MLE's, which can be evaluated numerically. We show that the probability mass function satisfies a simple recurrence equation linear in the two parameters, and propose the quadratic distance estimator (QDE) which can be computed with an ineratively reweighted least-squares algorithm. the QDE is easy to calculate and admits a simple expression for its asymptotic variance-covariance matrix. We compute this matrix for the MLE's and the QDE for various values of the parameters and see that the QDE has very high asymptotic efficiency. Finally, we present a numerical example. 相似文献
92.
Semiparametric estimation of plane similarities: application to fast computation of aeronautic loads
In the big data era, it is often needed to resolve the problem of parsimonious data representation. In this paper, the data under study are curves and the sparse representation is based on a semiparametric model. Indeed, we propose an original registration model for noisy curves. The model is built transforming an unknown function by plane similarities. We develop a statistical method that allows to estimate the parameters characterizing the plane similarities. The properties of the statistical procedure are studied. We show the convergence and the asymptotic normality of the estimators. Numerical simulations and a real-life aeronautic example illustrate and demonstrate the strength of our methodology. 相似文献
93.
Louis E. Baxter 《Alcoholism & Drug Abuse Weekly》2020,32(22):5-5
The question of whether or not doctors and other health care professionals on medication‐assisted treatment (MAT) are safe to practice medicine has been debated for the last few years since the advent of Food and Drug Administration (FDA)–approved MAT for opioid use disorder (OUD). The newly approved medications have been primarily buprenorphine formulations for OUD, naltrexone formulations for OUD and alcohol use disorder (AUD), and, most recently, an alpha 2‐adrenergic medication that specifically targets amelioration of opioid‐withdrawal symptoms from OUD (lofexidine). Quite frankly, the question of safety about medications to treat substance use disorder (SUD) has been asked since the development of methadone for OUD treatment more than 30 years ago. 相似文献
94.
95.
The classical unconditional exact p-value test can be used to compare two multinomial distributions with small samples. This general hypothesis requires parameter estimation under the null which makes the test severely conservative. Similar property has been observed for Fisher's exact test with Barnard and Boschloo providing distinct adjustments that produce more powerful testing approaches. In this study, we develop a novel adjustment for the conservativeness of the unconditional multinomial exact p-value test that produces nominal type I error rate and increased power in comparison to all alternative approaches. We used a large simulation study to empirically estimate the 5th percentiles of the distributions of the p-values of the exact test over a range of scenarios and implemented a regression model to predict the values for two-sample multinomial settings. Our results show that the new test is uniformly more powerful than Fisher's, Barnard's, and Boschloo's tests with gains in power as large as several hundred percent in certain scenarios. Lastly, we provide a real-life data example where the unadjusted unconditional exact test wrongly fails to reject the null hypothesis and the corrected unconditional exact test rejects the null appropriately. 相似文献
96.
Is there such a thing as “institutional readiness” for integrated watershed management? One element of readiness is the ability of managers with watershed-related responsibilities to identify the policy and management objectives of potential partners. The geographic areas encompassed by large watersheds are under the overlapping jurisdictions of many agencies and organizations from each sector (public, non-profit, and private) as well as private landowners. Developing a watershed-based institutional atlas is a promising strategy for coping with this jurisdictional complexity. The authors examine the potential for developing such an atlas in the Maumee River watershed of Ohio, Indiana, and Michigan, and they assess other signals of readiness and partnerships in progress in the basin. 相似文献
97.
Expressing Estimators of Expected Quality Adjusted Survival as Functions of Nelson-Aalen Estimators 总被引:1,自引:0,他引:1
Quality adjusted survival has been increasingly advocated in clinical trials to be assessed as a synthesis of survival and quality of life. We investigate nonparametric estimation of its expectation for a general multistate process with incomplete follow-up data. Upon establishing a representation of expected quality adjusted survival through marginal distributions of a set of defined events, we propose two estimators for expected quality adjusted survival. Expressed as functions of Nelson-Aalen estimators, the two estimators are strongly consistent and asymptotically normal. We derive their asymptotic variances and propose sample-based variance estimates, along with evaluation of asymptotic relative efficiency. Monte Carlo studies show that these estimation procedures perform well for practical sample sizes. We illustrate the methods using data from a national, multicenter AIDS clinical trial. 相似文献
98.
Analyzing scanner data in brand management activities presents unique difficulties due to the vast quantity of the data. Time series methods that are able to handle the volume effectively often are inappropriate due to the violation of many statistical assumptions in the data characteristics. We examine scanner data sets for three brand categories and examine properties associated with many time series forecasting methods. Many violations are found with respect to linearity, normality, autocorrelation, and heteroscedasticity. With this in mind we compare the forecasting ability of neural networks that require no assumptions to two of the more robust time series techniques. Neural networks provide similar forecasts to Bayesian vector autoregression (BVAR), and both outperform generalized autoregressive conditional herteroscedasticty (GARCH) models. 相似文献
99.
100.
Carlo C. Jaeger Jette Krause Armin Haas Rupert Klein Klaus Hasselmann 《Risk analysis》2008,28(4):815-823
The recent decision of the U.S. Supreme Court on the regulation of CO2 emissions from new motor vehicles( 1 ) shows the need for a robust methodology to evaluate the fraction of attributable risk from such emissions. The methodology must enable decisionmakers to reach practically relevant conclusions on the basis of expert assessments the decisionmakers see as an expression of research in progress, rather than as knowledge consolidated beyond any reasonable doubt.( 2,3,4 ) This article presents such a methodology and demonstrates its use for the Alpine heat wave of 2003. In a Bayesian setting, different expert assessments on temperature trends and volatility can be formalized as probability distributions, with initial weights (priors) attached to them. By Bayesian learning, these weights can be adjusted in the light of data. The fraction of heat wave risk attributable to anthropogenic climate change can then be computed from the posterior distribution. We show that very different priors consistently lead to the result that anthropogenic climate change has contributed more than 90% to the probability of the Alpine summer heat wave in 2003. The present method can be extended to a wide range of applications where conclusions must be drawn from divergent assessments under uncertainty. 相似文献