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101.
Incorporation of historical controls using semiparametric mixed models   总被引:1,自引:0,他引:1  
The analysis of animal carcinogenicity data is complicated by various statistical issues. A topic of recent debate is how to control for the effect of the animal's body weight on the outcome of interest, the onset of tumours. We propose a method which incorporates historical information from the control animals in previously conducted experiments. We allow non-linearity in the effects of body weight by modelling the relationship nonparametrically through a penalized spline. A simple extension of the penalized spline model allows the relationship between weight and the onset of tumour to vary from one experiment to another.  相似文献   
102.
This study investigates the relative roles of school district and school-level decision-makers in the implementation of effective substance use prevention curricula. Drawing on a "Site-Based Management" approach to effective decision-making, we hypothesized that schools whose personnel played active decision-making roles would be more likely to implement effective curricula than those in which decision-making was the prerogative of school district personnel. Study data comprised 1369 questionnaires completed by a representative national sample of both district-level prevention coordinators and middle school-based lead prevention teachers. From the perspective of the lead prevention teachers, the school district-level prevention coordinator was more influential than school staff in selecting effective prevention curricula. However, we did find some support for our hypothesis from our district-level informants, who indicated that community groups and advisory committees also play a modest role in the selection of such curricula.  相似文献   
103.
Interactivity has been shown to be a critical element of effective drug abuse prevention programs. This study examined the contents of Project Towards No Drug Abuse, a program that has revealed strong effects only when delivered in a highly interactive version. Types of teacher and student interactive messages were identified. It is speculated that explicit action on the part of the teacher to have students make statements and ask questions of one another may be the essence of effective drug education program delivery. Suggestions for future research on interactivity were made.  相似文献   
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Using a creative interdisciplinary method of enquiry, this article seeks to exorcise the spectres of revolutionary creolisation embedded in George Washington Cable’s 1880 novel The Grandissimes. It probes, in particular, the secreted traces of the Creole diaspora triggered by the Haitian Revolution of 1791–1804, and attempts to peel back the manifold layers of ideological occlusion embedded in the (ostensibly white, Anglo-American) narrative frame of Cable’s omniscient narrator and his protagonist Joseph Frowenfeld, which suppress the connections between inter-American identities across diverse, revolutionary, creolistic worlds in Louisiana and the Gulf South. Unlike other studies examining traces of the Haitian Revolution in The Grandissimes, which tend to focus on the parallels between fictional and historical figures in Cable’s southern romance, this article dissects the subtle allusions to the revolution and the attendant diaspora found in the plantation infrastructures and the urban landscape of Cable’s Louisiana. In so doing, it demonstrates how Saint-Domingan migrants affirmed and reinvigorated the cultural landscape of the ‘Creole’ South and ‘circumvented’ the ideological spread of ‘Americanness’ at the time of the Louisiana Purchase, and during successive moments thereafter.  相似文献   
106.
Objective: Develop and validate measures of adolescents' attitudes about sexual relationship rights. Methods: Items were completed by students in a large U.S. city (N = 655). The authors conducted an exploratory factor analysis, evaluated internal consistency, and assessed construct validity, including ability to predict sexual behavior at 1-year follow-up. Results: Factor analysis identified 2 distinct factors, comprising attitudes about rights to refuse unwanted sexual activity (5 items) and express sexual engagement needs (5 items) in a sexual relationship. The measures showed sound evidence of reliability and construct validity. Conclusions: The psychometric evidence supports the use of these measures in adolescent sexual health research.  相似文献   
107.
In this paper, we examine the potential of immigration to strengthen fiscal sustainability, which is under pressure by an ageing population in many European countries. We look at a particularly challenging case, namely that of Denmark, which has extensive tax-financed welfare programmes that provide a high social safety net. The analysis is based on a forecast of the entire Danish economy made using a dynamic computable general equilibrium model with overlapping generations. We present life cycle estimates of the potential fiscal impact of immigration considering the cost of immigration on the margin as well as on average. The main conclusion is that immigrants from Western countries have a positive fiscal impact, while immigrants from non-Western countries have a large negative one, which is also the case when considering only non-refugee immigrants. The negative effect is caused by both a weak labour market performance and early retirement in combination with the universal Danish welfare schemes.  相似文献   
108.
This article surfaces issues about the often-used but widely under-reported practice of working with advisory fora. We critically reflect on our experiences working with an advisory network when co-designing a research study about a ‘sensitive’ subject. We discuss the following: 1) How the network evolved as a matter of ethical and pragmatic choices; 2) Potential issues when discussing sensitive issues ‘outside’ of the participatory or participant context; and 3) Practical and epistemic issues involved in (not) ‘taking’ advice. We suggest that although sensitive research is more conventionally aligned with more ‘radical’ forms of participatory practice, advisory networks can present a useful and sometimes more appropriate form of inclusion and engagement for some advisors and for some types of research study. The article should, therefore, be of interest to a wide range of academic and practice-based health and social care staff and, in particular, those who plan to use advisory fora in their work.  相似文献   
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This article describes the results of research on the demographic, housing, psychosocial characteristics, and service needs of a sample of homeless people with HIV disease. Results show that respondents are similar in demographic and housing characteristics to the general homeless population. On average, respondents report high levels of stress and depression, moderate satisfaction with perceived social support availability, moderate beliefs in their ability to influence health related outcomes, moderate levels of self-efficacy, and low levels of physical and psychosocial disability. A range of services was identified as both helpful and useful in supporting a stable living arrangement. Implications for social policy, service provision, and research are discussed.  相似文献   
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